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DL-Mandelic acid

CAS No.
90-64-2
Chemical Name:
DL-Mandelic acid
Synonyms
Mandelic;Amygdalinic acid;Mandellic acid;Amygdalic acid;Almond acid;Pregabalin EP Impurity C;alpha-Hydroxy-benzeneacetic acid;(2RS)-2-Hydroxy-2-phenylacetic Acid;-MandeL;Uromaline
CBNumber:
CB3287471
Molecular Formula:
C8H8O3
Molecular Weight:
152.15
MDL Number:
MFCD00064250
MOL File:
90-64-2.mol
MSDS File:
SDS
Last updated:2023-11-24 16:35:22

DL-Mandelic acid Properties

Melting point 119-121 °C (lit.)
Boiling point 214.6°C (rough estimate)
alpha [α]D20 -0.5~+0.5° (c=2, H2O)
Density 1.30
vapor pressure 0.01 Pa (50 °C)
refractive index 1.4810 (estimate)
storage temp. Store below +30°C.
solubility 139g/l
pka 3.85(at 25℃)
form Crystals or Crystalline Powder
color White
PH 2.3 (10g/l, H2O)
Odor faint odor
optical activity [α]/D 0±1°, c = 5 in H2O
Water Solubility 150 g/L (20 ºC)
Sensitive Light Sensitive
Merck 14,5717
BRN 510011
InChIKey IWYDHOAUDWTVEP-UHFFFAOYSA-N
LogP 0.5 at 23℃
CAS DataBase Reference 90-64-2(CAS DataBase Reference)
FDA UNII V1PY73ZXPE
NIST Chemistry Reference Benzeneacetic acid, «alpha»-hydroxy-(90-64-2)
EPA Substance Registry System Mandelic acid (90-64-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  36/37/38-22
Safety Statements  22-24/25-37/39-26-36
WGK Germany  3
RTECS  OO6300000
TSCA  Yes
HS Code  29181990
NFPA 704
0
2 0

DL-Mandelic acid price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHR3199 Mandelic Acid pharmaceutical secondary standard, certified reference material 90-64-2 1G $173 2024-03-01 Buy
Sigma-Aldrich 8.06913 DL-Mandelic Acid forsynthesis 90-64-2 250g $57.1 2024-03-01 Buy
Sigma-Aldrich 8.06913 DL-Mandelic Acid forsynthesis 90-64-2 1kg $178 2024-03-01 Buy
Sigma-Aldrich 8.06913 DL-Mandelic Acid forsynthesis 90-64-2 5kg $444 2024-03-01 Buy
Sigma-Aldrich 41605 DL-Mandelic acid analytical standard 90-64-2 100mg $116 2024-03-01 Buy
Product number Packaging Price Buy
PHR3199 1G $173 Buy
8.06913 250g $57.1 Buy
8.06913 1kg $178 Buy
8.06913 5kg $444 Buy
41605 100mg $116 Buy

DL-Mandelic acid Chemical Properties,Uses,Production

Chemical Properties

White rhomboidal crystals, decompose when exposed to light. Soluble in ether and isopropanol, soluble in ethanol and water; R-form melting point is 133°C, [α]-159.73° (ethanol), gradually racemic at 160°C. S-form melting point is 133.8°C, [α]+156.57° (water).

Uses

Organic synthesis, medicine (urinary antiseptic).

Uses

DL-Mandelic acid may be used as an analytical reference standard for the determination of DL-mandelic acid in:
Human urine samples by high performance liquid chromatography (HPLC) equipped with ultraviolet (UV) detector.
Rat urine samples by gas chromatography-mass spectrometry (GC-MS) with selected ion monitoring (SIM) detection.

Preparation

Mandelic acid can be prepared by the hydrolysis of amygdalin with sulfuric acid or of mandelonitrile with hydrochloric acid. The mandelonitrile can be prepared by the action of hydrocyanic acid on benzaldehyde, and by the action of sodium or potassium cyanide on the sodium bisulfite addition product of benzaldehyde. The procedure described differs from earlier methods in that the sodium bisulfite addition compound of benzaldehyde is prepared in the presence of sodium cyanide and the nitrile is formed immediately.
synthesis of mandelic acid

Definition

ChEBI: Mandelic acid is a 2-hydroxy monocarboxylic acid that is acetic acid in which two of the methyl hydrogens are substituted by phenyl and hydroxyl groups. It has a role as an antibacterial agent and a human xenobiotic metabolite. It is a 2-hydroxy monocarboxylic acid and a member of benzenes. It derives from an acetic acid. It is a conjugate acid of a mandelate. Exists in stereoisomeric forms. The properties are those of the dl-form.

General Description

DL-Mandelic acid is an aromatic hydrocarbon metabolite of styrene.

Hazard

Toxic by ingestion.

Flammability and Explosibility

Not classified

Safety Profile

Poison by intramuscular route. Moderately toxic by ingestion. Continued absorption can cause kidney irritation. When heated to decomposition it emits acrid smoke and irritating fumes.

Global( 568)Suppliers
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Suzhou Actchem Co., Ltd.
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View Lastest Price from DL-Mandelic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
mandelic acid pictures 2024-03-19 mandelic acid
90-64-2
US $20.00 / KG 20KG 99% 1000kg Hebei Yime New Material Technology Co., Ltd.
Mandelic acid pictures 2024-03-01 Mandelic acid
90-64-2
US $0.00-0.00 / kg 1kg 98% 1000kg Changsha Staherb Natural Ingredients Co., Ltd.
DL-Mandelic acid pictures 2023-12-25 DL-Mandelic acid
90-64-2
US $25.00 / kg 1kg 99% 20000 Hebei Jingbo New Material Technology Co., Ltd
  • mandelic acid pictures
  • mandelic acid
    90-64-2
  • US $20.00 / KG
  • 99%
  • Hebei Yime New Material Technology Co., Ltd.
  • Mandelic acid pictures
  • Mandelic acid
    90-64-2
  • US $0.00-0.00 / kg
  • 98%
  • Changsha Staherb Natural Ingredients Co., Ltd.
  • DL-Mandelic acid pictures
  • DL-Mandelic acid
    90-64-2
  • US $25.00 / kg
  • 99%
  • Hebei Jingbo New Material Technology Co., Ltd
(n)-mandelic acid DL-MANDELIC ACID611-72-3 MANDELICACIDANDITSCOMMONSALTS alpha-Hydroxyphenylacetic acid Kyselina 2-fenyl-2-hydroxyethanova Kyselina mandlova kyselina2-fenyl-2-hydroxyethanova kyselinamandlova Paramandelic acid paramandelicacid phenyl-glycolicaci p-Mandelic acid Racemic mandelic acid racemicmandelicacid Uromaline DL-Mandelic acid Mandelic Acid (500 mg) Mandelic Acid (AS) Mandelic Acid (500 mg) (AS) DL-Mandelic acid, 99+% 100GR Mandelic aCld acidomandelico alpha-hydroxy-alpha-toluicaci alpha-hydroxy-benzeneaceticaci alpha-Phenylhydroxyacetic acid alpha-Toluic acid, alpha-hydroxy- Amigdalinicacid Benzeneaceticacid,-hydroxy- Benzoglycolic acid Glycolic acid, phenyl- -Hydroxyben-zenaceticacid RARECHEM AL BO 1098 TIMTEC-BB SBB007730 PHENYLHYDROXYACETIC ACID PHENYLGLYCOLLIC ACID PHENYLGLYCOLIC ACID A-HYDROXYBENZENE ACETIC ALPHA-HYDROXY-ALPHA-TOLUIC ACID ALPHA-HYDROPHENYLACETIC ACID (±)-Mandelicacid,99% α-Hydroxybenzeneacetic acid DL-MANDELIC ACID, FOR GRAVIMETRIC DETERMINATION (OF ZR) 99+% DL-MANDELIC ACID 98% Dl-MandelicAcid99.5% DL-A-HYDROXYPHENYLACETIC ACID DL-AMYGDALIC ACID DL-ALPHA-HYDROXYPHENYLACETIC ACID DL-O-HYDROXYPHENYLACETIC ACID DL-PHENYLGLYCOLIC ACID MANDELIC ACID, DL- MANDELIC(D,L-) ACID (+/-)-à-hydroxyphenylacetic acid DL-Amygdalic Acid α-Hydroxyphenylacetic acid (±)-α-Hydroxyphenylacetic acid Pregabalin Impurity 41 (Pregabalin EP Impurity C) DL-MandelicAcid> Mandelic Acid ( (2RS)-2-Hydroxy-2-phenylacetic Acid) DL-MANDELIC ACID FOR SYNTHESIS Homatropine EP Impurity C