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Ketoprofen

Used in Particular Diseases
Ketoprofen
Ketoprofen structure
CAS No.
22071-15-4
Chemical Name:
Ketoprofen
Synonyms
aneol;Dexal;Topre;Iso-K;ORUDIS;Epatec;Fastum;Lertus;ru4733;Toprec
CBNumber:
CB3299418
Molecular Formula:
C16H14O3
Formula Weight:
254.28
MOL File:
22071-15-4.mol

Ketoprofen Properties

Melting point:
93-96°C
Boiling point:
357.5°C (rough estimate)
Density 
1.1565 (rough estimate)
refractive index 
1.5600 (estimate)
storage temp. 
0-6°C
solubility 
Slightly soluble in chloroform and methanol.
pka
pKa 5.94(MeOH/H2O) (Uncertain)
form 
solid
Merck 
14,5305
InChIKey
DKYWVDODHFEZIM-UHFFFAOYSA-N
CAS DataBase Reference
22071-15-4(CAS DataBase Reference)
NIST Chemistry Reference
Ketoprofen(22071-15-4)
EPA Substance Registry System
Benzeneacetic acid, 3-benzoyl-.alpha.-methyl-(22071-15-4)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T
Risk Statements  25-36/37/38-23/24/25
Safety Statements  26-45-36/37/39
RIDADR  2811
WGK Germany  3
RTECS  UE7570000
TSCA  Yes
HazardClass  6.1(b)
PackingGroup  III
HS Code  29183000
Toxicity LD50 orally in rats: 101 mg/kg (Ueno)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Ketoprofen price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 34016 Ketoprofen VETRANAL , analytical standard 22071-15-4 100mg-r $59.7 2018-11-13 Buy
Sigma-Aldrich 1356632 Ketoprofen United States Pharmacopeia (USP) Reference Standard 22071-15-4 200mg $348 2018-11-13 Buy
TCI Chemical K0038 Ketoprofen >98.0%(HPLC)(T) 22071-15-4 25g $155 2018-11-22 Buy
TCI Chemical K0038 Ketoprofen >98.0%(HPLC)(T) 22071-15-4 250g $896 2018-11-22 Buy
Alfa Aesar J62702 Ketoprofen 22071-15-4 25g $231 2018-11-13 Buy

Ketoprofen Chemical Properties,Uses,Production

Used in Particular Diseases

Acute Gouty Arthritis:
Dosage and Frequency: 75 mg four times a day

Chemical Properties

White Crystalline Solid

Uses

Natural Vitamin B12. analog

Uses

Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.

Uses

Anti-inflammatory; analgesic

Indications

Ketoprofen (Orudis) is indicated for use in rheumatoid and osteoarthritis, for mild to moderate pain, and in dysmenorrhea. The most frequently reported side effects are GI (dyspepsia, nausea, abdominal pain, diarrhea, constipation, and flatulence) and CNS related (headache, excitation). Edema and increased blood urea nitrogen have also been noted in more than 3% of patients. Ketoprofen can cause fluid retention and increases in plasma creatinine, particularly in the elderly and in patients taking diuretics.

Definition

ChEBI: An oxo monocarboxylic acid that consists of propionic acid substituted by a 3-benzoylphenyl group at position 2.

brand name

Actron (Bayer); Orudis (Wyeth); Oruvail (Wyeth).

General Description

Ketoprofen (Orudis, Rhodis) and suprofen (Profenal) areclosely related to fenoprofen in their structures, properties,and indications. Even though ketoprofen has been approvedfor OTC use (Orudis KT, Actron), its GI side effects aresimilar to indomethacin, and therefore its useshould be closely monitored, especially in patients with GIor renal problems.

Contact allergens

Ketoprofen is an anti-inflammatory drug, used both topically and systemically. It is above all a photoaller- gen, responsible for photoallergic or photo-worsened contact dermatitis, with sun-induced, progressive, severe, and durable reactions. Recurrent photosensitiv- ity is possible for many years. Photosensitivities are expected to thiophene-phenylketone derivatives such as tiaprofenic acid and suprofen, to ketoprofen esters such as piketoprofen, and to benzophenone derivatives (see above) such as fenofibrate and benzophenone-3. Concomitant photosensitivities without clinical rel- evance have been observed to fenticlor, tetrachloro- salicylanilide, triclosan, tribromsalan, and bithionol.

Ketoprofen Preparation Products And Raw materials

Raw materials

Preparation Products


Ketoprofen Suppliers

Global( 335)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3203 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21930 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 495 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Hangzhou FandaChem Co.,Ltd.
0086 158 5814 5714 (Mobile; WhatsApp; Telegram)
+86-571-56059825 fandachem@gmail.com CHINA 2617 55
PI & PI BIOTECH INC.
020-81716320
020-81716319 Sales@pipitech.com CHINA 2543 55
Hubei XinRunde Chemical Co., Ltd.
+8615102730682; +8618874586545
02783214688 bruce@xrdchem.cn CHINA 541 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 24196 60
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1750 55

View Lastest Price from Ketoprofen manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Ketoprofen
22071-15-4
US $1.00 / KG 1G 98% 100KG career henan chemical co
2018-08-20 Ketoprofen
22071-15-4
US $1.00 / KG 1KG 98% 100KG career henan chemical co

Ketoprofen Spectrum


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