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1-OLEOYL-2-ACETYL-SN-GLYCEROL

CAS No.
86390-77-4
Chemical Name:
1-OLEOYL-2-ACETYL-SN-GLYCEROL
Synonyms
OAG;Oleoylacetylglycerol;DG(18:1(9Z)/2:0/0:0);1-Oleyl-2-acetylglycerol;(OAG) oleyl-acetyl glycerol;Sn-1-oleoyl-2-acetylglycerol;1-Olein-2-acetyl-sn-glycerol;1-OLEOYL-2-ACETYL-SN-GLYCEROL;2-ACETYL-1-OLEOYL-SN-GLYCEROL;(±)-1-Oleoyl-2-acetylglycerol
CBNumber:
CB3303463
Molecular Formula:
C23H42O5
Molecular Weight:
398.58
MDL Number:
MFCD00166985
MOL File:
86390-77-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:37
Product description Number Pack Size Price
1-Oleoyl-2-acetyl-sn-glycerol ≥97% (TLC), oil O6754 5mg $197
1-Oleoyl-2-acetyl-sn-glycerol ≥97% (TLC), oil O6754 10mg $317
1-Oleoyl-2-acetyl-sn-glycerol - CAS 86390-77-4 - Calbiochem Cell-permeable diacylglycerol analog that activates Ca2+-dependent protein kinase C. 495414 5mg $106
1-Oleoyl-2-acetyl-sn-glycerol - CAS 86390-77-4 - Calbiochem Cell-permeable diacylglycerol analog that activates Ca2+-dependent protein kinase C. 495414 25mg $355
1-Oleoyl-2-acetyl-sn-glycerol ≥95% 62600 5mg $63

1-OLEOYL-2-ACETYL-SN-GLYCEROL Properties

Boiling point 490.0±15.0 °C(Predicted)
Density 0.980±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility ethanol: 20 mg/mL
form oil
pka 13.89±0.10(Predicted)
color yellow
biological source synthetic (organic)
BRN 8168731
Stability Temperature Sensitive. This compound can rearrange to the 1,3-isomer in solution or during prolonged storage.
InChI InChI=1S/C23H42O5/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(26)27-20-22(19-24)28-21(2)25/h10-11,22,24H,3-9,12-20H2,1-2H3/b11-10-/t22-/m0/s1
InChIKey PWTCCMJTPHCGMS-YRBAHSOBSA-N
SMILES C(OC[C@@H](OC(C)=O)CO)(=O)CCCCCCC/C=C\CCCCCCCC
CAS DataBase Reference 86390-77-4(CAS DataBase Reference)
UNSPSC Code 12352211
NACRES NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H302-H315-H319-H331-H336-H351-H361d-H372-H412
Precautionary statements  P201-P273-P301+P312+P330-P302+P352-P304+P340+P311-P308+P313
PPE Eyeshields, Gloves
WGK Germany  3
10-23
Storage Class 10 - Combustible liquids

1-OLEOYL-2-ACETYL-SN-GLYCEROL price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich O6754 1-Oleoyl-2-acetyl-sn-glycerol ≥97% (TLC), oil 86390-77-4 5mg $197 2026-04-30 Buy
Sigma-Aldrich O6754 1-Oleoyl-2-acetyl-sn-glycerol ≥97% (TLC), oil 86390-77-4 10mg $317 2026-04-30 Buy
Sigma-Aldrich 495414 1-Oleoyl-2-acetyl-sn-glycerol - CAS 86390-77-4 - Calbiochem Cell-permeable diacylglycerol analog that activates Ca2+-dependent protein kinase C. 86390-77-4 5mg $106 2026-04-30 Buy
Sigma-Aldrich 495414 1-Oleoyl-2-acetyl-sn-glycerol - CAS 86390-77-4 - Calbiochem Cell-permeable diacylglycerol analog that activates Ca2+-dependent protein kinase C. 86390-77-4 25mg $355 2026-04-30 Buy
Cayman Chemical 62600 1-Oleoyl-2-acetyl-sn-glycerol ≥95% 86390-77-4 5mg $63 2026-04-30 Buy
Product number Packaging Price Buy
O6754 5mg $197 Buy
O6754 10mg $317 Buy
495414 5mg $106 Buy
495414 25mg $355 Buy
62600 5mg $63 Buy

1-OLEOYL-2-ACETYL-SN-GLYCEROL Chemical Properties,Uses,Production

Chemical Properties

Colourless to light yellow oil

Uses

Activator of phospholipid-dependent protein kinase C; and stimulator of secretion and aggregation in blood platelets.x

Uses

18:1-2:0 DG (1-oleoyl-2-acetyl-sn-glycerol) has been used as a diacyl glycerol (DAG) analog to test its impact on DAG-sensitive channels in thalamocortical (TC) neurons. It may be used as an internal standard for retention time calibration in ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF MS)for blood sample lipid quantification. It may also be used as a protein kinase C (PKC) activator in adrenal glands.

Definition

ChEBI: 1-Oleoyl-2-acetyl-sn-glycerol is a 1,2-diglyceride.

General Description

18:1-2:0 DG, also called 1-oleoyl-2-acetyl-sn-glycerol (OADG), is a synthetic analog of diacyl glycerol (DAG) and is membrane permeable.

Biochem/physiol Actions

1-Oleoyl-2-acetyl-sn-glycerol is a synthetic, cell permeable diacylglycerol analog. It is often used as an activator of calcium-dependent protein kinase C (PKC).

868368-11-0
86390-77-4
Synthesis of 1-OLEOYL-2-ACETYL-SN-GLYCEROL from 9-Octadecenoic acid (9Z)-, (2R)-2-(acetyloxy)-3-[(2,2,2-trichloroacetyl)oxy]propyl ester

1-OLEOYL-2-ACETYL-SN-GLYCEROL Preparation Products And Raw materials

Raw materials

Preparation Products

1-OLEOYL-2-ACETYL-SN-GLYCEROL Suppliers

Global( 80)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32343 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684; sales@rrkchem.com China 57422 58
J & K SCIENTIFIC LTD. 18210857532; 18210857532 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15838 69
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32321 50
Syntechem Co.,Ltd info@syntechem.com China 12984 57
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51395 80
Alfa Chemistry 1-516-6625404 support@alfa-chemistry.com United States 9171 60
1-[CIS-9-OCTADECENOYL]-2-ACETYL-SN-GLYCEROL 2-ACETYL-1-OLEOYL-SN-GLYCEROL 1-OLEOYL-2-ACETYL-SN-GLYCEROL 1-O-9Z-OCTADECENOYL-2-O-ACETYL-SN-GLYCEROL 1-(cis-9-Octadecenoyl)-2-acetyl-sn-glycerol, 2-Acetyl-1-oleoyl-sn-glycerol, OAG 1-Oleyl-2-acetylglycerol 1-o-Octadecenoyl-2-o-acetylglycerol 9-Octadecenoic acid (9Z)-, (2S)-2-(acetyloxy)-3-hydroxypropyl ester 9-Octadecenoic acid (Z)-, 2-(acetyloxy)-3-hydroxypropyl ester, (S)- Oleoylacetylglycerol Sn-1-oleoyl-2-acetylglycerol (9Z)-9-Octadecenoic Acid 2-(Acetyloxy)-3-hydroxypropyl Ester (S)-2-acetoxy-3-hydroxypropyl oleate OAG (9Z)-9-Octadecenoic acid (2S)-2-(acetyloxy)-3-hydroxypropyl ester DG(18:1(9Z)/2:0/0:0) 1-Oleoyl-2-acetyl-sn-glycerol (OAG) 1-Oleoyl-2-acetyl-sn-glycerol - CAS 86390-77-4 - Calbiochem (OAG) oleyl-acetyl glycerol 1-Olein-2-acetyl-sn-glycerol 1-Oleoyl-2-acetyl-sn-glycerol, PKC activator 1-Oleoyl-2-acetyl-sn-glycerol (±)-1-Oleoyl-2-acetylglycerol 86390-77-4 Lipids Neutral Glycerides Glycerides Diradylglycerols BioChemical Biochemicals and Reagents Chemical Activators Activators Fatty Acid Derivatives & Lipids Glycerols Protein Kinase Inhibitors and Activators