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Bis-Propargyl-PEG13

CAS No.
1351373-50-6
Chemical Name:
Bis-Propargyl-PEG13
Synonyms
CAS_1351373-50-6;Bis-propargyl-PEG12;Bis-Propargyl-PEG13;4,7,10,13,16,19,22,25,28,31,34,37,40-Tridecaoxatritetraconta-1,42-diyne;Bis-propargyl-PEG12/4,7,10,13,16,19,22,25,28,31,34,37,40-Tridecaoxatritetraconta-1,42-diyne
CBNumber:
CB33062422
Molecular Formula:
C30H54O13
Molecular Weight:
622.74
MDL Number:
MFCD31811435
MOL File:
1351373-50-6.mol
Last updated:2023-04-23 13:52:06

Bis-Propargyl-PEG13 Properties

solubility Soluble in Water, DMSO, DMF, DCM

Bis-Propargyl-PEG13 price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B523918 Bis-propargyl-PEG13 1351373-50-6 5mg $45 2021-12-16 Buy
BroadPharm BP-22514 Bis-propargyl-PEG13 98% 1351373-50-6 250mg $350 2021-12-16 Buy
Activate Scientific AS107811 Bis-propargyl-PEG12 97% 1351373-50-6 250mg $435 2021-12-16 Buy
BroadPharm BP-22514 Bis-propargyl-PEG13 98% 1351373-50-6 500mg $540 2021-12-16 Buy
Apolloscientific BIPG1305 Bis-Propargyl-PEG13 1351373-50-6 250mg $681 2021-12-16 Buy
Product number Packaging Price Buy
B523918 5mg $45 Buy
BP-22514 250mg $350 Buy
AS107811 250mg $435 Buy
BP-22514 500mg $540 Buy
BIPG1305 250mg $681 Buy

Bis-Propargyl-PEG13 Chemical Properties,Uses,Production

Description

Bis-propargyl-PEG13 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

structure and hydrogen bonding

Bis-propargyl-PEG13 comprises two propargyl groups which can form triazole linkages with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions. The hydrophilic PEG units help improve the solubility of the molecule in aqueous media.

Bis-Propargyl-PEG13 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 26)Suppliers
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SHANGHAI T&W PHARMACEUTICAL CO., LTD.
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TargetMol Chemicals Inc.
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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Jilin Chinese Academy of Sciences-yanshen Technology
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Aladdin Scientific
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 4111 55
Jinan elephant international trading co., LTD 13006575422@163.com China 6357 58
Bis-Propargyl-PEG13 Bis-propargyl-PEG12 CAS_1351373-50-6 4,7,10,13,16,19,22,25,28,31,34,37,40-Tridecaoxatritetraconta-1,42-diyne Bis-propargyl-PEG12/4,7,10,13,16,19,22,25,28,31,34,37,40-Tridecaoxatritetraconta-1,42-diyne 1351373-50-6 C30H54O13