ChemicalBook >> CAS DataBase List >>DIHYDROMETHYSTICIN
DIHYDROMETHYSTICIN
- CAS No.
- 19902-91-1
- Chemical Name:
- DIHYDROMETHYSTICIN
- Synonyms
- dhm;Nsc112159;PseudoMethysticin;DIHYDROMETHYSTICIN;DIHYDROMETHYLSTICIN;7,8-dihydromethysticin;7,8-DIHYDROMETHYLSTICIN;Methysticin, 7,8-dihydro-;Dihydroanesthetic capsicin;Dihydromethysticin ((+)-Dihydromethysticin)
- CBNumber:
- CB3307966
- Molecular Formula:
- C15H16O5
- Molecular Weight:
- 276.28
- MDL Number:
- MFCD00221731
- MOL File:
- 19902-91-1.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:03:09
| storage temp. | 2-8°C |
|---|---|
| solubility | Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly) |
| Boiling point | 476.1±45.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3(Predicted) |
| Melting point | 117-118 °C |
| color | White to Off-White |
| BRN | 91699 |
| Stability | Hygroscopic |
| InChIKey | RSIWXFIBHXYNFM-NSHDSACASA-N |
| LogP | 1.810 (est) |
| FDA UNII | FZ66MQ73GS |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
DIHYDROMETHYSTICIN price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 52007 | (+)-Dihydromethysticin analytical standard | 19902-91-1 | 5mg | $539 | 2022-05-15 | Buy |
| Cayman Chemical | 27644 | Dihydromethysticin | 19902-91-1 | 5mg | $238 | 2024-03-01 | Buy |
| TRC | B203530 | (6S)-6-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one | 19902-91-1 | 10mg | $375 | 2021-12-16 | Buy |
| ChemScene | CS-4245 | Dihydromethysticin | 19902-91-1 | 10mg | $420 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HBL0000233 | (+)-DIHYDROMETHYSTICIN 95.00% | 19902-91-1 | 5MG | $933.26 | 2021-12-16 | Buy |
DIHYDROMETHYSTICIN Chemical Properties,Uses,Production
Description
Dihydromethysticin is a kavalactone originally isolated from P. methysticum (kava-kava) that has diverse biological activities, including efflux transporter inhibitory, antinociceptive, and neuroprotective properties. Dihydromethysticin is a P-glycoprotein (P-gp) inhibitor that increases uptake of the P-gp substrate calcein AM by 50% in P388 mouse leukemia cancer cells overexpressing P-gp when used at a concentration of 54.6 μM. Dihydromethysticin (275 mg/kg) has analgesic activity, increasing the latency to tail withdrawal in the tail-flick assay in mice. It also decreases the infarct size in a mouse model of ischemia induced by microbipolar coagulation of the left middle cerebral artery (MCA) when administered at a dose of 10 mg/kg.
Uses
(6S)-6-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one, is used in toxicity studies through in vitro analysis. This complex is found in the roots of kava plant.
Definition
ChEBI: Dihydromethysticin is a member of 2-pyranones and an aromatic ether.
DIHYDROMETHYSTICIN Preparation Products And Raw materials
Global( 125)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9702 | 58 |
| Changsha Staherb Natural Ingredients Co., Ltd. | +86-0731-84213302 +8618374838656 | sales@staherb.cn | China | 1025 | 58 |
View Lastest Price from DIHYDROMETHYSTICIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | DHM; DIHYDROMETHYSTICIN
19902-91-1
|
US $0.00 / MG | 20MG | >95% HPLC | 1000KG | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2020-01-13 | DIHYDROMETHYSTICIN
19902-91-1
|
US $9.80 / KG | 1KG | ≥98% | 20 tons | Career Henan Chemical Co |
-
- DHM; DIHYDROMETHYSTICIN
19902-91-1
- US $0.00 / MG
- >95% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- DIHYDROMETHYSTICIN
19902-91-1
- US $9.80 / KG
- ≥98%
- Career Henan Chemical Co
19902-91-1(DIHYDROMETHYSTICIN)Related Search:
6-(2-(1,3-benzodioxol-5-yl)ethyl)-5,6-dihydro-4-methoxy-2h-pyran-2-on(s)
6-dihydro-4-methoxy-6-(3,4-(methylenedioxy)phenethyl)-(s)-2h-pyran-2-on
7,8-dihydromethysticin
dhm
DIHYDROMETHYLSTICIN
7,8-DIHYDROMETHYLSTICIN
5,6-Dihydro-4-methoxy-6-[2-(1,3-benzodioxol-5-yl)ethyl]-2H-pyran-2-one
6-[2-(1,3-Benzodioxol-5-yl)ethyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[3,4-(methylenedioxy)phenethyl]-, (S)-
2H-Pyran-2-one, 6-[2-(1,3-benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-, (S)-
Methysticin, 7,8-dihydro-
Nsc112159
PseudoMethysticin
(6S)-6-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4-Methoxy-2H-pyran-2-one
DIHYDROMETHYSTICIN
Dihydromethysticin ((+)-Dihydromethysticin)
2H-Pyran-2-one, 6-[2-(1,3-benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-, (6S)-
Dihydromethysticin,Inhibitor,inhibit,CYPs,Cytochrome P450
(S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one
Dihydroanesthetic capsicin
19902-91-1
Coumarins