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N-EPSILON-ACETYL-L-LYSINE

CAS No.
692-04-6
Chemical Name:
N-EPSILON-ACETYL-L-LYSINE
Synonyms
Nεlys(ac);NSC 102777;H-LYS(AC)-OH;LYSINE(AC)-OH;H-L-LYS(AC)-OH;Nε-Ac-L-Lys-OH;Nε-Acetyllysine;N6-Acetyllysine;N-E-ACETYL-L-LYSINE
CBNumber:
CB3308387
Molecular Formula:
C8H16N2O3
Formula Weight:
188.22
MOL File:
692-04-6.mol

N-EPSILON-ACETYL-L-LYSINE Properties

Melting point 250 °C (dec.)(lit.)
Boiling point 323.23°C (rough estimate)
Density 1.1793 (rough estimate)
refractive index 1.4500 (estimate)
storage temp. -20°C
pka 2.53±0.24(Predicted)
form Powder
color White
Water Solubility Soluble in water (miscible), and 80% acetic acid (50 mg/ml).
Sensitive Hygroscopic
InChIKey DTERQYGMUDWYAZ-ZETCQYMHSA-N
CAS DataBase Reference 692-04-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
HS Code  29241900

N-EPSILON-ACETYL-L-LYSINE price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A4021 Nω-Acetyl-L-lysine 692-04-6 1g $98.9 2022-05-15 Buy
Sigma-Aldrich A4021 Nω-Acetyl-L-lysine 692-04-6 5g $297 2022-05-15 Buy
TCI Chemical A2652 Nε-Acetyl-L-lysine >98.0%(T) 692-04-6 1g $40 2022-04-27 Buy
Alfa Aesar J64139 N(epsilon)-Acetyl-L-lysine, 99% 692-04-6 1g $54.8 2021-12-16 Buy
Alfa Aesar J64139 N(epsilon)-Acetyl-L-lysine, 99% 692-04-6 5g $163 2021-12-16 Buy
Product number Packaging Price Buy
A4021 1g $98.9 Buy
A4021 5g $297 Buy
A2652 1g $40 Buy
J64139 1g $54.8 Buy
J64139 5g $163 Buy

N-EPSILON-ACETYL-L-LYSINE Chemical Properties,Uses,Production

Description

Acetyllysine (or acetylated lysine) is an acetyl-derivative of the amino acid lysine. There are multiple forms of acetyllysine - this article refers to N-ε-acetyl-L-lysine. The other form is N-α-acetyl-Llysine.
In proteins, the acetylation of lysine residues is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Non-histone proteins are acetylated as well. Unlike the functionally similar methyllysine, acetyllysine does not carry a positive charge on its side chain.
Histone acetyltransferases (HATs) catalyze the addition of acetyl groups from acetyl-CoA onto certain lysine residues of histones and non-histone proteins. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from acetylated lysines.
Acetyllysine can be synthesized from lysine by the selective acetylation of the terminal amine group.

Chemical Properties

white crystalline powder

Uses

N-Epsilon-acetyl-l-lysine is used in the metabolomics study on the combined effect of cocaine and ethanol via liquid chromatography-mass spectrometry metabolomics approach.

Definition

ChEBI: An N6-acyl-L-lysine where the N6-acyl group is specified as acetyl.

Biochem/physiol Actions

Nε-Acetyl-L-lysine (L-AcK) is an R-chain N-acetylated α amino acid used together with other lysine analogues to differentiate and characterized various aminoacylases and regulator 2 (Sir2) enzymes/sirtuins.

N-EPSILON-ACETYL-L-LYSINE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 118)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
371-66670886 info@dakenchem.com China 16600 58
ATK CHEMICAL COMPANY LIMITED
21-51619050 ivan@atkchemical.com China 26810 60
GenicBio Limited
+86-21-37621270 service@genicbio.com CHINA 991 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29960 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 23035 58
Chongqing Chemdad Co., Ltd
+8613650506873 sales@chemdad.com CHINA 37442 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47500 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19231 58
GL Biochem (Shanghai) Ltd.
+86-021-61263370 +86-18901917034 xingli@glbiochem.com CHINA 3905 58
GL Biochem(Binhai) Ltd.
021-61263370 +8615301650015 wuqiuyan@glschina.com CHINA 2976 58

View Lastest Price from N-EPSILON-ACETYL-L-LYSINE manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-07-06 N-EPSILON-ACETYL-L-LYSINE
692-04-6
US $1.00 / KG 1KG 99% 20kg Career Henan Chemical Co
N-E-ACETYL-L-LYSINE N-EPSILON-ACETYL-L-LYS N-EPSILON-ACETYL-L-LYSINE H-LYS(AC)-OH H-L-LYS(AC)-OH (2S)-6-acetamido-2-amino-hexanoic acid N-epsilon-acetyllysine LYSINE(AC)-OH (2S)-2-amino-6-acetamidohexanoic acid N6-Acetyllysine Nε-Acetyllysine Nε-Ac-L-Lys-OH N-epsilon-Acetyl-L-lysine,99% 6-N-Acetyl-L-lysine-6-N-Acetyl-L-lysine-d8 (S)-6-acetaMido-2-aMinohexanoic acid Nε-Acetyl-L-lysine epsilon-Acetyl-L-lysine epsilon-N-Acetyllysine NSC 102777 omega-N-Acetyl-L-lysine -Acetyl-L-lysine Nε-Acetyl-L-lysine≥ 99% (HPLC) L-Lysine, N6-acetyl- N-EPSILON-ACETYL-L-LYSINE USP/EP/BP N-epsilon-acetyl-laevo-lysine lys(ac) 692-04-6 CH3CONHCH24CHNH2CO2H Amino Acids and Peptides BioChemical Biochemicals and Reagents A - H Modified Amino Acids A - H Amino Acids Modified Amino Acids