ChemicalBook >> CAS DataBase List >>Integrin Antagonist 1 (hydrochloride)
Integrin Antagonist 1 (hydrochloride)
- CAS No.
- 1629249-40-6
- Chemical Name:
- Integrin Antagonist 1 (hydrochloride)
- Synonyms
- GSK-3008348 hydrochloride;Integrin Antagonist 1 (hydrochloride);(3S)-3-[3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl]-4-{(3S)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]-1-pyrrolidinyl}butanoic acid
- CBNumber:
- CB33121109
- Molecular Formula:
- C29H38ClN5O2
- Molecular Weight:
- 524.11
- MDL Number:
- MFCD29924721
- MOL File:
- 1629249-40-6.mol
Last updated:2025-04-17 18:22:24
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Integrin Antagonist 1 (hydrochloride) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Crysdot | CD31003119 | IntegrinAntagonist1hydrochloride 98+% | 1629249-40-6 | 5mg | $243 | 2021-12-16 | Buy |
| Crysdot | CD31003119 | IntegrinAntagonist1hydrochloride 98+% | 1629249-40-6 | 10mg | $347 | 2021-12-16 | Buy |
| Crysdot | CD31003119 | IntegrinAntagonist1hydrochloride 98+% | 1629249-40-6 | 50mg | $1042 | 2021-12-16 | Buy |
| Crysdot | CD31003119 | IntegrinAntagonist1hydrochloride 98+% | 1629249-40-6 | 100mg | $1459 | 2021-12-16 | Buy |
Integrin Antagonist 1 (hydrochloride) Chemical Properties,Uses,Production
Uses
GSK 3008348 hydrochloride is a small molecule integrin αvβ6 antagonist, extracted from patent WO/2014154725A1, example 1. The affinity (pIC50) for the human - a 6 protein in the Fluorescence Polarisation Assay for GSK 3008348 (hydrochloride) is 8.1, whereas its affinity in the cell Adhesion Assays was for: ανβ6 (pIC50 = 8.4); ανβ3 (pIC50 = 6); ανβ5 (pIC50 = 6.9); ανβ8 (pIC50 = 7.7).
References
[1] Anderson Niall Andrew, et al. Preparation of naphthyridine derivatives useful as αvβ6 integrin antagonists. From PCT Int. Appl. (2014), WO 2014154725 A1 20141002.
Integrin Antagonist 1 (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
Integrin Antagonist 1 (hydrochloride) Suppliers
Global( 13)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32282 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19654 | 58 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2982 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4660 | 60 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| Absin Bioscience Inc. | 021-38015121 18438616290 | wulan@absin.cn | China | 24731 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5536 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-025-66113011 18626450290 | cb5@aikonchem.com | China | 10359 | 58 |
| Chengdu Peter-like Biotechnology Co., Ltd. | 028-81700200 13308200041 | 2851167782@qq.com | China | 11183 | 58 |
Integrin Antagonist 1 (hydrochloride)
(3S)-3-[3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl]-4-{(3S)-3-[2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl]-1-pyrrolidinyl}butanoic acid
GSK-3008348 hydrochloride
1629249-40-6