ChemicalBook >> CAS DataBase List >>Madrasin
Madrasin
- CAS No.
- 374913-63-0
- Chemical Name:
- Madrasin
- Synonyms
- CS-2251;Madrasin;DD00107587;DDD00107587;DDD-00107587;Madrasin >=98% (HPLC);DDD00107587;DD00107587;DDD-00107587;DDD-00107587,Madrasin,inhibit,Inhibitor,DDD 00107587;2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one;4(3H)-Pyrimidinone, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-
- CBNumber:
- CB33123143
- Molecular Formula:
- C16H17N5O2
- Molecular Weight:
- 311.34
- MDL Number:
- MFCD02233199
- MOL File:
- 374913-63-0.mol
- MSDS File:
- SDS
Last updated:2023-09-04 15:51:00
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P301+P312+P330 | |||||||||
NFPA 704 |
|
Madrasin price More Price(11)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML1409 | Madrasin ≥98% (HPLC) | 374913-63-0 | 5MG | $115 | 2023-06-20 | Buy |
Sigma-Aldrich | SML1409 | Madrasin ≥98% (HPLC) | 374913-63-0 | 25MG | $451 | 2023-06-20 | Buy |
Cayman Chemical | 20451 | Madrasin ≥95% | 374913-63-0 | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 20451 | Madrasin ≥95% | 374913-63-0 | 5mg | $93 | 2024-03-01 | Buy |
Cayman Chemical | 20451 | Madrasin ≥95% | 374913-63-0 | 10mg | $169 | 2024-03-01 | Buy |
Madrasin Chemical Properties,Uses,Production
Uses
Madrasin has been used as a spliceosome inhibitor to inhibit pre-mRNA processing in 3T3-L1 cells.
Definition
ChEBI: 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-1H-pyrimidin-4-one is a member of quinazolines.
Biochem/physiol Actions
Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly. Madrasin stalls spliceosome assembly at the A complex.
Madrasin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 59)Suppliers
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Madrasin
DD00107587
DDD00107587
DDD-00107587
DDD00107587;DD00107587;DDD-00107587
CS-2251
4(3H)-Pyrimidinone, 2-[(7-methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-
Madrasin >=98% (HPLC)
2-((7-Methoxy-4-methylquinazolin-2-yl)amino)-5,6-dimethylpyrimidin-4(3H)-one
DDD-00107587,Madrasin,inhibit,Inhibitor,DDD 00107587
2-(7-Methoxy-4-methyl-quinazolin-2-ylamino)-5,6-dimethyl-3H-pyrimidin-4-one 2-[(7-Methoxy-4-methyl-2-quinazolinyl)amino]-5,6-dimethyl-4(1H)-pyrimidinone (9CI) 4(1H)-Pyrimidinone, 2-[(7-methoxy-4-methy
374913-63-0
API