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ChemicalBook >> CAS DataBase List >>isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate

isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate

isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate Structure
isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate structure
CAS No.
1496551-77-9
Chemical Name:
isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
Synonyms
MK-3682;IDX21437;IDX 21437;IDX-21437;EOS-61179;Uprifosbuvir;Uprifosbuvir (MK-3682);D-Alanine, N-[[P(R),2'R]-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester;propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate;isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate
CBNumber:
CB33142975
Molecular Formula:
C22H29ClN3O9P
Molecular Weight:
545.91
MDL Number:
MOL File:
1496551-77-9.mol
Last updated:2025-12-05 14:33:18
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isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate Properties

Density 1.43±0.1 g/cm3(Predicted)
pka 9.39±0.10(Predicted)
form Solid
color White to off-white
FDA UNII JW31KPS26S

isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate Chemical Properties,Uses,Production

Uses

Uprifosbuvir is an antiviral agent. Uprifosbuvir is a NS5b inhibitor developed for the research of chronic hepatitis C virus[1].

References

[1] Klapars A, et al. Efficient synthesis of antiviral agent uprifosbuvir enabled by new synthetic methods. Chem Sci. 2021;12(26):9031-9036. DOI:10.1039/d1sc01978c

isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate Preparation Products And Raw materials

Raw materials

Preparation Products

isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
CR Corporation Limited 		+8613062833949 fred.wen@crcorporation.cn China 8645 58
CD Chemical Group Limited 		+8615986615575 info@codchem.com China 20342 58
Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9307 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39035 58
Jinan elephant international trading co., LTD 13006575422@163.com China 6355 58
Shanghai zhigan biotechnology co., LTD zhiqianbio@126.com China 19778 58
Shanghai Dexuan Pharmaceutical Technology Co., Ltd 1701086315 dexuanpharma@126.com China 9475 58
Nanjing Wogni Chemical Co., Ltd. 15996452985 foxerhy@163.com China 4939 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
CR Corporation Limited 		58
CD Chemical Group Limited 		58
Henan Aochuang Chemical Co.,Ltd. 		58
TargetMol Chemicals Inc. 		58
Jinan elephant international trading co., LTD 58
Shanghai zhigan biotechnology co., LTD 58
Shanghai Dexuan Pharmaceutical Technology Co., Ltd 58
Nanjing Wogni Chemical Co., Ltd. 58

View Lastest Price from isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Uprifosbuvir pictures 2025-12-05 Uprifosbuvir
1496551-77-9
 US $84.00-328.00 / mg 99.73% 10g TargetMol Chemicals Inc.
  • Uprifosbuvir pictures
  • Uprifosbuvir
    1496551-77-9
  • US $84.00-328.00 / mg
  • 99.73%
  • TargetMol Chemicals Inc.

isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate Spectrum

isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate(1496551-77-9)1HNMR
isopropyl((R)-(((2R,3R,4R,5R)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-D-alaninate EOS-61179 MK-3682 propan-2-yl (2R)-2-[[[(2R,3R,4R,5R)-4-chloro-5-(2,4-dioxopyrimidin-1-yl)-3-hydroxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate Uprifosbuvir Uprifosbuvir (MK-3682) D-Alanine, N-[[P(R),2'R]-2'-chloro-2'-deoxy-2'-methyl-P-phenyl-5'-uridylyl]-, 1-methylethyl ester IDX 21437 IDX21437 IDX-21437 1496551-77-9 C22H29ClN3O9P