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ChemicalBook >> CAS DataBase List >>Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI)

Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI)

Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) Structure
Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) structure
CAS No.
111112-18-6
Chemical Name:
Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI)
Synonyms
LY195448 HCl;UNII-BR0DFE3GF6;Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI);111Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI)
CBNumber:
CB33178840
Molecular Formula:
C20H27ClN2O2
Molecular Weight:
362.9
MDL Number:
MOL File:
111112-18-6.mol
Last updated:2025-08-21 22:16:43
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Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) Properties

FDA UNII BR0DFE3GF6

Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) Chemical Properties,Uses,Production

Uses

LY-195448 hydrochloride is a phenethanolamine that exhibits anti-tumour activity across various murine tumour models. LY-195448 hydrochloride acts by blocking cells at metaphase. LY-195448 hydrochloride has demonstrated a lack of "standard" side effects commonly associated with cancer treatments, such as myelosuppression and gastrointestinal toxicity. LY-195448 hydrochloride was evaluated in a phase I trial, where it showed only mild and reversible side effects like hypotension, tachycardia, and tremor.

References

[1] Phase I clinical and pharmacokinetic study of LY 195448

Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 19962 58
Shanghai Merlot Chemical Co., LTD 15821661757 226174156@qq.com China 476 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29641 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Shanghai Merlot Chemical Co., LTD 58
TargetMol Chemicals Inc. 58

View Lastest Price from Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
LY195448 HCl pictures 2025-08-21 LY195448 HCl
111112-18-6
 US $2500.00-1980.00 / mg 10g TargetMol Chemicals Inc.
  • LY195448 HCl pictures
  • LY195448 HCl
    111112-18-6
  • US $2500.00-1980.00 / mg
  • TargetMol Chemicals Inc.
Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) UNII-BR0DFE3GF6 LY195448 HCl 111Benzamide,4-[3-[[(2R)-2-hydroxy-2-phenylethyl]amino]-3-methylbutyl]-, monohydrochloride(9CI) 111112-18-6 C20H26N2O2ClH