2,2,6,6-Tetramethylpiperidine
- CAS No.
- 768-66-1
- Chemical Name:
- 2,2,6,6-Tetramethylpiperidine
- Synonyms
- HTMP;TETRAMETHYLPIPERIDINE;2,2,6,6-TetramethyL;6-TetraMethylpiperidine;2,2,6,6-Teteamethyl-piperidine;2,2,6,6-Tetramethylpiperidine(Tmp);2,2,6;Norpempidine;2,2,6,6-Tetramethylp;2,2,6,6-Tetramethylpiperidien
- CBNumber:
- CB3320372
- Molecular Formula:
- C9H19N
- Molecular Weight:
- 141.25
- MDL Number:
- MFCD00005985
- MOL File:
- 768-66-1.mol
- MSDS File:
- SDS
Melting point | -59°C |
---|---|
Boiling point | 152 °C (lit.) |
Density | 0.837 g/mL at 25 °C (lit.) |
vapor pressure | 14 hPa (39 °C) |
refractive index |
n |
Flash point | 76 °F |
storage temp. | Store below +30°C. |
solubility | MISCIBLE |
pka | 11.07(at 25℃) |
form | Liquid |
color | Clear colorless to yellow |
Specific Gravity | 0.837 |
Water Solubility | MISCIBLE |
Sensitive | Air Sensitive |
BRN | 103296 |
InChIKey | RKMGAJGJIURJSJ-UHFFFAOYSA-N |
CAS DataBase Reference | 768-66-1(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 44N9S1YCFM |
NIST Chemistry Reference | Piperidine, 2,2,6,6-tetramethyl-(768-66-1) |
EPA Substance Registry System | Piperidine, 2,2,6,6-tetramethyl- (768-66-1) |
UNSPSC Code | 12352005 |
NACRES | NA.22 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() ![]() GHS02,GHS05,GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H226-H290-H302-H314 | |||||||||
Precautionary statements | P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
Hazard Codes | Xn,F,C | |||||||||
Risk Statements | 10-22-36/37/38 | |||||||||
Safety Statements | 26-37/39-16 | |||||||||
RIDADR | UN 1992 3/PG 3 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | TN4220000 | |||||||||
Autoignition Temperature | 290 °C | |||||||||
TSCA | Yes | |||||||||
HazardClass | 3 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29333999 | |||||||||
Toxicity | LD50 orally in Rabbit: 500 mg/kg | |||||||||
NFPA 704 |
|
2,2,6,6-Tetramethylpiperidine price More Price(33)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 8.18132 | 2,2,6,6-Tetramethylpiperidine for synthesis | 768-66-1 | 25mL | $114 | 2024-03-01 | Buy |
Sigma-Aldrich | 115754 | 2,2,6,6-Tetramethylpiperidine ≥99% | 768-66-1 | 5g | $44.7 | 2024-03-01 | Buy |
Sigma-Aldrich | 8.18132 | 2,2,6,6-Tetramethylpiperidine for synthesis | 768-66-1 | 100mL | $205 | 2024-03-01 | Buy |
Sigma-Aldrich | 115754 | 2,2,6,6-Tetramethylpiperidine ≥99% | 768-66-1 | 10g | $84 | 2024-03-01 | Buy |
TCI Chemical | T1051 | 2,2,6,6-Tetramethylpiperidine >98.0%(GC)(T) | 768-66-1 | 25mL | $113 | 2024-03-01 | Buy |
2,2,6,6-Tetramethylpiperidine Chemical Properties,Uses,Production
Chemical Properties
clear colorless to light yellow-green liquid
Uses
2,2,6,6-Tetramethylpiperidine is a hindered base used to prepare metallo-amide bases and selective generation of silylketene acetals. It is used in the preparation of hibarimicinone, (Z)-silylketene acetal and 4-substituted quinazoline. It acts as a precursor to Lithium tetramethylpiperidide and (2,2,6,6-Tetramethylpiperidin-1-yl)oxyl radical.
Uses
2,2,6,6-Tetramethylpiperidine is used in the syntheses of HMP-Y1, Hibarimicinone and HMP-P1, tyrosine kinase inhibitors.
Uses
The lithium amide has been used to efficiently ortho deprotonate pyridine-3-carboxamides.
Preparation
Many routes for the synthesis of TMP have been reported. One method starts with a conjugate addition reaction of ammonia to phorone. The intermediate triacetone amine is then reduced in a Wolff-Kishner reaction.
2,2,6,6-Tetramethylpiperidine Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Nanjing Liskon Biological Technology Co., Ltd | 025-52110956 +8613814852963 | sales@liskonchem.com | China | 7 | 58 |
Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2158 | 58 |
Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13783527580 | Lingzhiyue@aliyun.com | China | 3145 | 58 |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29792 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21632 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | FandaChem@Gmail.com | China | 8141 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32965 | 60 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2986 | 55 |
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View Lastest Price from 2,2,6,6-Tetramethylpiperidine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
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2024-06-16 | 2,2,6,6-tetramethyl-piperidin
768-66-1
|
US $0.00 / KG | 25KG | ≥99.0% | 5tons | Nanjing Liskon Biological Technology Co., Ltd | |
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2022-10-11 | 2,2,6,6-Tetramethylpiperidine
768-66-1
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
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2021-11-18 | 2,2,6,6-Tetramethylpiperidine
768-66-1
|
US $10.00 / Kg/Bag | 1Kg/Bag | 99% | 20 Tons | Hebei Zhanyao Biotechnology Co. Ltd |
-
- 2,2,6,6-tetramethyl-piperidin
768-66-1
- US $0.00 / KG
- ≥99.0%
- Nanjing Liskon Biological Technology Co., Ltd
-
- 2,2,6,6-Tetramethylpiperidine
768-66-1
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2,2,6,6-Tetramethylpiperidine
768-66-1
- US $10.00 / Kg/Bag
- 99%
- Hebei Zhanyao Biotechnology Co. Ltd
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