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ChemicalBook >> CAS DataBase List >>2,2,6,6-Tetramethylpiperidine

2,2,6,6-Tetramethylpiperidine

2,2,6,6-Tetramethylpiperidine Structure
2,2,6,6-Tetramethylpiperidine structure
CAS No.
768-66-1
Chemical Name:
2,2,6,6-Tetramethylpiperidine
Synonyms
HTMP;TETRAMETHYLPIPERIDINE;2,2,6,6-TetramethyL;6-TetraMethylpiperidine;2,2,6,6-Teteamethyl-piperidine;2,2,6,6-Tetramethylpiperidine(Tmp);2,2,6;Norpempidine;2,2,6,6-Tetramethylp;2,2,6,6-Tetramethylpiperidien
CBNumber:
CB3320372
Molecular Formula:
C9H19N
Molecular Weight:
141.25
MDL Number:
MFCD00005985
MOL File:
768-66-1.mol
MSDS File:
SDS
Last updated:2023-12-18 08:54:39
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2,2,6,6-Tetramethylpiperidine Properties

Melting point -59°C
Boiling point 152 °C (lit.)
Density 0.837 g/mL at 25 °C (lit.)
vapor pressure 14 hPa (39 °C)
refractive index n20/D 1.445(lit.)
Flash point 76 °F
storage temp. Store below +30°C.
solubility MISCIBLE
pka 11.07(at 25℃)
form Liquid
Specific Gravity 0.837
color Clear colorless to yellow
Water Solubility MISCIBLE
Sensitive Air Sensitive
BRN 103296
InChIKey RKMGAJGJIURJSJ-UHFFFAOYSA-N
CAS DataBase Reference 768-66-1(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 44N9S1YCFM
NIST Chemistry Reference Piperidine, 2,2,6,6-tetramethyl-(768-66-1)
EPA Substance Registry System Piperidine, 2,2,6,6-tetramethyl- (768-66-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS07
Signal word  Danger
Hazard statements  H226-H290-H302-H314
Precautionary statements  P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes  Xn,F,C
Risk Statements  10-22-36/37/38
Safety Statements  26-37/39-16
RIDADR  UN 1992 3/PG 3
WGK Germany  2
RTECS  TN4220000
Autoignition Temperature 290 °C
TSCA  Yes
HazardClass  3
PackingGroup  III
HS Code  29333999
Toxicity LD50 orally in Rabbit: 500 mg/kg
NFPA 704
3
3 0

2,2,6,6-Tetramethylpiperidine price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.18132 2,2,6,6-Tetramethylpiperidine for synthesis 768-66-1 25mL $114 2024-03-01 Buy
Sigma-Aldrich 115754 2,2,6,6-Tetramethylpiperidine ≥99% 768-66-1 5g $44.7 2024-03-01 Buy
Sigma-Aldrich 8.18132 2,2,6,6-Tetramethylpiperidine for synthesis 768-66-1 100mL $205 2024-03-01 Buy
Sigma-Aldrich 115754 2,2,6,6-Tetramethylpiperidine ≥99% 768-66-1 10g $84 2024-03-01 Buy
TCI Chemical T1051 2,2,6,6-Tetramethylpiperidine >98.0%(GC)(T) 768-66-1 25mL $113 2024-03-01 Buy
Product number Packaging Price Buy
8.18132 25mL $114 Buy
115754 5g $44.7 Buy
8.18132 100mL $205 Buy
115754 10g $84 Buy
T1051 25mL $113 Buy

2,2,6,6-Tetramethylpiperidine Chemical Properties,Uses,Production

Chemical Properties

clear colorless to light yellow-green liquid

Uses

2,2,6,6-Tetramethylpiperidine is a hindered base used to prepare metallo-amide bases and selective generation of silylketene acetals. It is used in the preparation of hibarimicinone, (Z)-silylketene acetal and 4-substituted quinazoline. It acts as a precursor to Lithium tetramethylpiperidide and (2,2,6,6-Tetramethylpiperidin-1-yl)oxyl radical.

Uses

2,2,6,6-Tetramethylpiperidine is used in the syntheses of HMP-Y1, Hibarimicinone and HMP-P1, tyrosine kinase inhibitors.

Uses

The lithium amide has been used to efficiently ortho deprotonate pyridine-3-carboxamides.

Preparation

Many routes for the synthesis of TMP have been reported. One method starts with a conjugate addition reaction of ammonia to phorone. The intermediate triacetone amine is then reduced in a Wolff-Kishner reaction.
Preparation of 2,2,6,6-Tetramethylpiperidine

2,2,6,6-Tetramethylpiperidine synthesis

45842-10-2
768-66-1
Synthesis of 2,2,6,6-Tetramethylpiperidine from Piperidinium, 2,2,6,6-tetramethyl-1-oxo-

2,2,6,6-Tetramethylpiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

2-METHOXY-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 5-FLUORO-2-PICOLINIC ACID 5-FORMYL-2,4-DIMETHOXYPYRIMIDINE 3-BROMO-2-((CYCLOPROPYLAMINO)METHYL)BENZALDEHYDE (E)-5-(2-CARBOXYVINYL)-2,4-DIMETHOXYPYRIMIDINE
3-CYANOPYRIDIN-4-YLBORONIC ACID 5-(TRIFLUOROMETHYL)-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 2-CHLORO-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 2-CYANOPYRIDIN-3-YLBORONIC ACID 3-METHOXY-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE
2-(3-METHOXYPHENYL)CYCLOHEXANONE 4-(TRIFLUOROMETHYL)-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 2,2,6,6-Tetramethylpiperidinooxy 6-CHLOROPYRIDINE-3,4-DICARBOXYLIC ACID 2-(TRIFLUOROMETHYL)-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE
2-Chloro-4-methoxypyrimidine-5-carbaldehyde 2-CYANO-5-BROMOPHENYLBORONIC ACID PINACOL ESTER 2-CHLOROPYRIDINE-3,4-DICARBOXYLIC ACID 4-CYANOPYRIDIN-3-YLBORONIC ACID 2-BROMO-6-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE
4-CHLORO-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE 2-(TRIFLUOROMETHYL)-4-ISOCYANATOPYRIDINE 3-FLUORO-2-(5,5-DIMETHYL-1,3,2-DIOXABORINAN-2-YL)BENZONITRILE

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2,2,6,6-Tetramethylpiperidine Suppliers

Global( 465)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Liskon Biological Technology Co., Ltd 		025-52110956 +8613814852963 sales@liskonchem.com China 7 58
Changzhou Ditong Chemical Co.,Ltd
+86-0519-88299272 info@edengenechem.com China 2169 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
Hangzhou FandaChem Co.,Ltd. 		008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3012 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418679 +86-18949832763 info@tnjchem.com China 2989 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Supplier Advantage
Nanjing Liskon Biological Technology Co., Ltd 		58
Changzhou Ditong Chemical Co.,Ltd
58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Hefei TNJ Chemical Industry Co.,Ltd. 		55
career henan chemical co 		58

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View Lastest Price from 2,2,6,6-Tetramethylpiperidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2,6,6-Tetramethylpiperidine pictures 2023-03-29 2,2,6,6-Tetramethylpiperidine
768-66-1
 US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
2,2,6,6-Tetramethylpiperidine pictures 2022-10-11 2,2,6,6-Tetramethylpiperidine
768-66-1
 US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
2,2,6,6-Tetramethylpiperidine pictures 2021-11-18 2,2,6,6-Tetramethylpiperidine
768-66-1
 US $10.00 / Kg/Bag 1Kg/Bag 99% 20 Tons Hebei Zhanyao Biotechnology Co. Ltd

2,2,6,6-Tetramethylpiperidine Spectrum

2,2,6,6-Tetramethylpiperidine(768-66-1)MS2,2,6,6-Tetramethylpiperidine(768-66-1)1HNMR2,2,6,6-Tetramethylpiperidine(768-66-1)13CNMR2,2,6,6-Tetramethylpiperidine(768-66-1)IR12,2,6,6-Tetramethylpiperidine(768-66-1)Raman

768-66-1(2,2,6,6-Tetramethylpiperidine)Related Search:

2,6-Lutidine 4-AMINO-2,2,6,6-TETRAMETHYLPIPERIDINE PURUM 97%,4-Amine-2,2,6,6-Tetramethylpiperidine DROPERIDOL Haloperidol 2,2,6,6-Tetramethylpiperidinooxy
2,2,6,6-Tetramethyl-4-piperidinol Triacetonamine Diphenoxylate PHENCYCLIDINE-D5 HYDROCHLORIDE 4-Oxo-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical
4-Amino-TEMPO, free radical 2,2,6,6-Tetramethyl-4-piperidone hydrochloride 3,5-Dibromo-4-oxo-2,2,6,6-tetramethylpiperidin-1-yl 1,2,2,6,6-PENTAMETHYLPIPERIDINE 4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical,4-Hydroxy-2,2,6,6-tetramethylpiperidine 1-oxyl, TEMPOL
Light Stabilizer 770 Light Stabilizer-944 4-Acetamido-2,2,6,6-tetramethylpiperidine 1-Oxyl Free Radical [Catalyst for Oxidation],4-Acetamido-2,2,6,6-tetramethylpiperidine N-oxyl

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2,2,6,6-TETRAMETHYLPIPERIDINE 2,2,6,6-tetramethyl-piperidin Norpempidine 2,2,6,6-Tetramethylpiperidine (HTMP) 2,2,6,6-Tetramethylpiperidine, 98+% 2,2,6,6-TETRAMETHYLPIPERIDINE, 99+% 2,2,6,6-Tetramethylpiperidien Piperidine, 2,2,6,6-tetramethyl- 2,2,6,6-tetramethylpiperidine(TEMP) 2,2,6,6-Tetramethylp 2,2,6,6-TetraMethylpiperidine, 98% 10GR 2,2,6,6-TetraMethylpiperidine, 98% 25GR 2,2,6,6-TETRAMETHYLPIPERIDINE FOR SYNTHE 2,2,6,6-TetraMethylpiperidine, 97+% 2,2,6,6-Tetramethylpiperidine USP/EP/BP 2,2,6 HTMP TETRAMETHYLPIPERIDINE 6-TetraMethylpiperidine 2,2,6,6-TetramethyL 2,2,6,6-Teteamethyl-piperidine 2,2,6,6-Tetramethylpiperidine(Tmp) 2,2,6,6-TETRAMETHYLPIEPERIDINE 2,2,6,6-Tetramethyl piperdine 768-66-1 768661 C9H19N AMINE Building Blocks Organic Bases Piperidines Synthetic Reagents Heterocyclic Building Blocks Fine Chemical Industrial/Fine Chemicals Piperidines, Piperidones, Piperazines Piperidine API intermediates Organic BasesBuilding Blocks Chemical Synthesis Heterocyclic Building Blocks Piperidines Synthetic Reagents 768-66-1