DFB
- CAS No.
- 15332-10-2
- Chemical Name:
- DFB
- Synonyms
- DFB;3,3'-Difluorobenzaldazine;1,2-Bis(3-fluorobenzylidene)hydrazine;3,3' Difluorobenzaldazine,3,3'Difluorobenzaldazine;[(3-FLUOROPHENYL)METHYLENE]HYDRAZONE-3-FLUOROBENZALDEHYDE;Benzaldehyde, 3-fluoro-, 2-[(3-fluorophenyl)methylene]hydrazone;1-(3-fluorophenyl)-N-[(Z)-(3-fluorophenyl)methylideneamino]methanimine
- CBNumber:
- CB3322679
- Molecular Formula:
- C14H10F2N2
- Molecular Weight:
- 244.24
- MDL Number:
- MFCD03653615
- MOL File:
- 15332-10-2.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H400 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P273-P391-P501 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-50/53 |
| Safety Statements | 60-61 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
DFB price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Tocris | 1625 | DFB ≥99%(HPLC) | 15332-10-2 | 10 | $101 | 2021-12-16 | Buy |
| Tocris | 1625 | DFB ≥99%(HPLC) | 15332-10-2 | 50 | $428 | 2021-12-16 | Buy |
| TRC | D100068 | DFB | 15332-10-2 | 10mg | $85 | 2021-12-16 | Buy |
| Usbiological | 255131 | DFB | 15332-10-2 | 10mg | $353 | 2021-12-16 | Buy |
| ApexBio Technology | B6806 | DFB | 15332-10-2 | 10mg | $156 | 2021-12-16 | Buy |
DFB Chemical Properties,Uses,Production
Uses
DFB is an allosteric potentiator of mGluR-5.
Definition
ChEBI: Bis(3-fluorobenzylidene)hydrazine is an azine and a member of monofluorobenzenes.
Biological Activity
Novel allosteric potentiator of the metabotropic glutamate receptor mGlu 5 . Devoid of agonist activity itself, but potentiates (3-6-fold) the action of agonists at mGlu 5 without any effect at other mGlu subtypes (EC 50 for potentiation = 2-5.3 μ M).
in vivo
3,3'-Difluorobenzaldazine (40-100 nmol; icv) attenuates the locomotor hyperactivity, motor incoordination, and cognitive impairment induced by Ketamine[2].
| Animal Model: | Male NMRI and ICR mice (8-9 weeks, 33-40 g)[2] |
| Dosage: | 40-100 nmol (~9.7-24.4 μg) |
| Administration: | ICV |
| Result: | Attenuated the locomotor hyperactivity, motor incoordination, and cognitive impairment induced by Ketamine. |
DFB Preparation Products And Raw materials
Raw materials
Preparation Products
DFB Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4128 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15839 | 69 | |
| Zhengzhou Guancheng Laboratory equipment Sales | 0371-88888888 272369594 | 2723695949@qq.com | China | 5009 | 50 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71829 | 60 |
| MQ (shanghai) Pharmaceuticals Co., Ltd. | 13761635123 | 1014988033@qq.com | China | 4966 | 55 |
| BOC Sciences | -- | info@bocsci.com | USA | 0 | 65 |
View Lastest Price from DFB manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-28 | 3,3'-Difluorobenzaldazine
15332-10-2
|
US $143.00-583.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- 3,3'-Difluorobenzaldazine
15332-10-2
- US $143.00-583.00 / mg
- TargetMol Chemicals Inc.