ChemicalBook >> CAS DataBase List >>2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
- CAS No.
- 835616-61-0
- Chemical Name:
- 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
- Synonyms
- 2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione;2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindole-1,3-dione;Thalidomide 5-fluoride;2-(2,6-dioxopiperidin-3-yl)-5-fluoro-2,3-dihydro-1H-isoindole-1,3-dione;135588;Thali-5F;Light purple to off white powder;2-(2,6-dioxo-3-piperidyl)-5-fluoro-isoindoline-1,3-dione;2-(2,6-Dioxo-3-piperidinyl)-5-fluoro-1,3-isoindolinedione;? 2-(2,6-Dioxopiperidin-3-yl)-5- difluoroisoindoline-1,3-dione
- CBNumber:
- CB33266857
- Molecular Formula:
- C13H9FN2O4
- Molecular Weight:
- 276.22
- MDL Number:
- MFCD30188075
- MOL File:
- 835616-61-0.mol
Last updated:2024-07-02 08:55:06
| Boiling point | 521.5±45.0 °C(Predicted) |
|---|---|
| Density | 1.570±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO: 83.33 mg/mL (301.68 mM) |
| pka | 10.65±0.40(Predicted) |
| form | Solid |
| color | Off-white to gray |
| InChI | InChI=1S/C13H9FN2O4/c14-6-1-2-7-8(5-6)13(20)16(12(7)19)9-3-4-10(17)15-11(9)18/h1-2,5,9H,3-4H2,(H,15,17,18) |
| InChIKey | MPQLCQKBYRSPNA-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=C(F)C=C2)C(=O)N1C1CCC(=O)NC1=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H361 |
| Precautionary statements | P201-P202-P264-P270-P281-P308+P313-P310-P330-P405-P501 |
2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Ambeed | A1004509 | 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione 97% | 835616-61-0 | 250mg | $35 | 2021-12-16 | Buy |
| Ambeed | A1004509 | 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione 97% | 835616-61-0 | 1g | $70 | 2021-12-16 | Buy |
| Ambeed | A1004509 | 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione 97% | 835616-61-0 | 5g | $220 | 2021-12-16 | Buy |
| Ambeed | A1004509 | 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione 97% | 835616-61-0 | 10g | $300 | 2021-12-16 | Buy |
| Acrotein | H-7889 | 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione 97% | 835616-61-0 | 10g | $348.33 | 2021-12-16 | Buy |
2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione Chemical Properties,Uses,Production
Description
2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione is a thalidomide analog that can be useful in PROTAC research.
Uses
Thalidomide 5'- fluoro (2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione) is a derivative of Thalidomide, commonly used as a precursor to PROTAC® Degraders that hijacks cereblon as the E3 ubiquitin ligase component. Supplied with a fluoro functional handle at a position known not to significantly affect binding to cereblon, ready for conjugation to a linker/target protein ligand.
storage
Store at +4°C
2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 129)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7621 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 19536 | 58 |
| Shanghai Worldyang Chemical Co.,Ltd. | +86-021-56795779 +8613651600618 | sales@worldyachem.com | China | 1080 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
| NINGBOBENKANGJS PHARMTECHCO., LTD | +8615990591583 15990591583 | CHINA | 2029 | 58 | |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4022 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23555 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
View Lastest Price from 2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-10-19 | 2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindole-1,3-dione
835616-61-0
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2022-07-25 | 2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
835616-61-0
|
US $0.00-0.00 / kg | 1kg | 98.0%min | 100kg | Changzhou Guiding Bio-Tech. Co.,Ltd. |
-
- 2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindole-1,3-dione
835616-61-0
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
835616-61-0
- US $0.00-0.00 / kg
- 98.0%min
- Changzhou Guiding Bio-Tech. Co.,Ltd.
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-
135588
2-(2,6-Dioxo-3-piperidinyl)-5-fluoro-1H-isoindole-1,3(2H)-dione
? 2-(2,6-Dioxopiperidin-3-yl)-5- difluoroisoindoline-1,3-dione
Light purple to off white powder
2-(2,6-Dioxo-3-piperidinyl)-5-fluoro-1,3-isoindolinedione
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fl...
2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
2-(2,6-dioxopiperidin-3-yl)-5-fluoroisoindole-1,3-dione
Thalidomide 5-fluoride
2-(2,6-dioxopiperidin-3-yl)-5-fluoro-2,3-dihydro-1H-isoindole-1,3-dione
H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-5-fluoro-
2-(2,6-dioxo-3-piperidyl)-5-fluoro-isoindoline-1,3-dione
Thali-5F
835616-61-0
pharmaceutical