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Pimelic acid

Pimelic acid
Pimelic acid structure
CAS No.
111-16-0
Chemical Name:
Pimelic acid
Synonyms
Pimelate;NSC-30112;PiMelic aci;pilericacid;PIMELIC ACID;Pileric acid;PEMILIC ACID;Dimelic acid;PIMELINIC ACID;HEPTANE DIACID
CBNumber:
CB3329360
Molecular Formula:
C7H12O4
Formula Weight:
160.17
MOL File:
111-16-0.mol

Pimelic acid Properties

Melting point:
103-105 °C(lit.)
Boiling point:
212 °C10 mm Hg(lit.)
Density 
1,329 g/cm3
refractive index 
1.4352 (estimate)
Flash point:
212°C/10mm
storage temp. 
Store below +30°C.
solubility 
ethanol: 0.1 g/mL, clear to very faintly hazy
pka
4.71(at 25℃)
form 
Powder
color 
White to slightly beige
Water Solubility 
25 g/L (13 ºC)
Merck 
14,7431
BRN 
1210024
Stability:
Stable. Incompatible with oxidizing agents, bases. Combustible.
InChIKey
WLJVNTCWHIRURA-UHFFFAOYSA-N
CAS DataBase Reference
111-16-0(CAS DataBase Reference)
NIST Chemistry Reference
Heptanedioic acid(111-16-0)
EPA Substance Registry System
Heptanedioic acid(111-16-0)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  TK3677000
Hazard Note  Irritant
TSCA  Yes
HS Code  29171990
Toxicity LD50 orally in Rabbit: 7000 mg/kg
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Pimelic acid price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P45001 Pimelic acid 98% 111-16-0 25g $43.1 2018-11-13 Buy
Sigma-Aldrich P45001 Pimelic acid 98% 111-16-0 100g $136 2018-11-13 Buy
TCI Chemical P0435 Pimelic Acid >98.0%(GC)(T) 111-16-0 25g $47 2018-11-22 Buy
TCI Chemical P0435 Pimelic Acid >98.0%(GC)(T) 111-16-0 100g $150 2018-11-22 Buy
Alfa Aesar A18495 Pimelic acid, 98+% 111-16-0 25g $27.9 2018-11-13 Buy

Pimelic acid Chemical Properties,Uses,Production

Description

Pimelic acid is the organic compound with the formula HO2C(CH2)5CO2H which has been synthesized from cyclohexanone and from salicylic acid. In the former route, the additional carbon is supplied by dimethyloxalate, which reacts with the enolate.
This acid (heptanedioic acid), from the Greek pimelh (pimele fat), as adipic acid, was isolated from oxidized fats. It was obtained in 1884 by Ganttner F et al. as a product of ricinoleic acid (hydroxylated oleic acid) from castor oil.

Chemical Properties

white solid

Definition

ChEBI: An alpha,omega-dicarboxylic acid that is pentane with two carboxylic acid groups at positions C-1 and C-5.

Enzyme inhibitor

This dicarboxylic acid (FWfree-acid = 160.17 g/mol; CAS 111-16-0; pK1 = 4.46 and pK2 = 5.58), also known as heptanedioic acid, is soluble in water (5 g/100 mL at 20°C). Pimelate is excreted in elevated amounts in urine in individuals with disorders in mitochondrial and peroxisomal b-oxidation, for which it is of significant diagnostic value.Target (s) :2-aminoadipate aminotransferase; 4-aminobutyrate aminotransferase; carbamoyl- phosphate synthetase; carboxy-cis,cis-muconate cyclase; glutamate decarboxylase, Ki = 0.81 mM; kynurenine:oxoglutarate aminotransferase; and 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase.

Purification Methods

Crystallise the acid from water or from *benzene containing 5% diethyl ether. [Beilstein 1 IV 2003.]

Pimelic acid Preparation Products And Raw materials

Raw materials

Preparation Products


Pimelic acid Suppliers

Global( 238)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 23983 58
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19919 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21930 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20680 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32457 55
Xiamen AmoyChem Co., Ltd
+86 (0)592-605 1114
sales@amoychem.com CHINA 6374 58
Kingfirst chemical (nanjing) co.,ltd
86-25-84522992
86-25-84774616 or 1617 marketing@kingfirstchem.com CHINA 60 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20094 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 12233 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 4660 58

View Lastest Price from Pimelic acid manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-04-03 Pimelic acid in stock GMP Factory
111-16-0
US $1.00 / KG 1KG GMP Factory in China Top 3 largest production capacity Factory Chemwill Asia Co.,Ltd.

Pimelic acid Spectrum


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