ChemicalBook >> CAS DataBase List >>PF-5190457
PF-5190457
- CAS No.
- 1334782-79-4
- Chemical Name:
- PF-5190457
- Synonyms
- PF-5190457;PF-05190457;PF-05190457 >=95% (HPLC);PF 5190457,Growth hormone secretagogue receptor,PF 05190457,PF-5190457,PF5190457,GHSR,Inhibitor,PF05190457,inhibit;1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone;(R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone;Ethanone, 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-
- CBNumber:
- CB33303958
- Molecular Formula:
- C29H32N6OS
- Molecular Weight:
- 512.67
- MDL Number:
- MOL File:
- 1334782-79-4.mol
- MSDS File:
- SDS
Last updated:2023-09-20 16:43:00
| Density | 1.41±0.1 g/cm3(Predicted) |
|---|---|
| storage temp. | room temp |
| solubility | DMSO: 250 mg/mL (487.64 mM) |
| form | powder |
| pka | 8.38±0.20(Predicted) |
| color | white to beige |
| optical activity | [α]/D +45 to +55°, c = 0.5 in methanol |
| FDA UNII | FF33NL9U5G |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
PF-5190457 price More Price(13)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PZ0270 | PF-05190457 ≥95% (HPLC) | 1334782-79-4 | 5MG | $115 | 2023-06-20 | Buy |
| Sigma-Aldrich | PZ0270 | PF-05190457 ≥95% (HPLC) | 1334782-79-4 | 25MG | $451 | 2023-06-20 | Buy |
| Tocris | 6350 | PF05190457 ≥98%(HPLC) | 1334782-79-4 | 25 | $332 | 2021-12-16 | Buy |
| Tocris | 6350 | PF05190457 ≥98%(HPLC) | 1334782-79-4 | 5 | $86 | 2021-12-16 | Buy |
| TRC | P293935 | PF5190457 | 1334782-79-4 | 10mg | $145 | 2021-12-16 | Buy |
PF-5190457 Chemical Properties,Uses,Production
Uses
PF 5190457 is a potent, selective, and orally bioavailable ghrelin receptor inverse agonist.
Biochem/physiol Actions
PF-05190457 is an orally available, potent and selective ghrelin receptor inverse agonist. PF-05190457 potently increases insulin secretion in glucose-stimulated human islets.
storage
Store at -20°C
PF-5190457 Preparation Products And Raw materials
Raw materials
Preparation Products
PF-5190457 Suppliers
Global( 35)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 | info@chemlin.com.cn | China | 17938 | 64 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
1334782-79-4(PF-5190457)Related Search:
PF-05212384
[(3R)-1-[2-[1-(4-Chloro-1H-pyrazol-1-yl)cyclopropyl]-3H-imidazo[4,5-b]pyridin-5-yl]-3-piperidinyl]-1-pyrrolidinyl-methanone methanesulfonate
PF-04691502
1H-Indole-2-carboxamide, 4-methoxy-N-[(1S)-3-methyl-1-[[[(1S)-2-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]-3-(phosphonooxy)propyl]amino]carbonyl]butyl]-
PF 477736
1of3
PF-5190457
1-[2-[(1R)-2,3-Dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3,5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone
PF-05190457 >=95% (HPLC)
PF-05190457
PF 5190457,Growth hormone secretagogue receptor,PF 05190457,PF-5190457,PF5190457,GHSR,Inhibitor,PF05190457,inhibit
Ethanone, 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-
(R)-2-(2-methylimidazo[2,1-b]thiazol-6-yl)-1-(2-(5-(6-methylpyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-2,7-diazaspiro[3.5]nonan-7-yl)ethanone
1334782-79-4