ChemicalBook >> CAS DataBase List >>HC≡C-CH2-PEG8-SH

HC≡C-CH2-PEG8-SH

CAS No.
1422540-92-8
Chemical Name:
HC≡C-CH2-PEG8-SH
Synonyms
HC≡C-CH2-PEG8-SH;Propargyl-PEG8-SH;3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yne-1-thiol
CBNumber:
CB33309420
Molecular Formula:
C19H36O8S
Molecular Weight:
424.55
MDL Number:
MFCD31747072
MOL File:
1422540-92-8.mol
Last updated:2023-02-23 14:24:01

HC≡C-CH2-PEG8-SH Properties

Boiling point 490.3±45.0 °C(Predicted)
Density 1.086±0.06 g/cm3(Predicted)
pka 9?+-.0.10(Predicted)

HC≡C-CH2-PEG8-SH price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
purepeg 437908 HC≡C-CH2-PEG8-SH min.95% 1422540-92-8 250mg $194 2021-12-16 Buy
Product number Packaging Price Buy
437908 250mg $194 Buy

HC≡C-CH2-PEG8-SH Chemical Properties,Uses,Production

Biological Activity

Propargyl-PEG8-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

HC≡C-CH2-PEG8-SH Preparation Products And Raw materials

Raw materials

Preparation Products

HC≡C-CH2-PEG8-SH Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4955 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223 psaitong@jm-bio.com China 29834 58
Affinity(Wuhan)Ltd. 15841022315 sales@affinitytech.cn China 2479 58
HC≡C-CH2-PEG8-SH Propargyl-PEG8-SH 3,6,9,12,15,18,21,24-Octaoxaheptacos-26-yne-1-thiol 1422540-92-8