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ChemicalBook >> CAS DataBase List >>1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE

1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE

1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Structure
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE structure
CAS No.
174689-39-5
Chemical Name:
1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE
Synonyms
SR 59230A;SR59230AHCl;SR 59230A HYDROCHLORIDE;SR 59230A >=98% (HPLC), powder;3-(2-ETHYLPHENOXY)-1-((1S)-1,2,3,4-TETRA-HYDRONAPHTH-1-YLAMINO)-(2S)-2-PROPANOL OXALATE;(S)-1-(2-Ethylphenoxy)-3-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)amino)propan-2-ol oxalate;3-(2-Ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphth-1-yl]amino]-(2S)-2-propanol oxalate salt;1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE;hyperthermia,adrenoceptor,Adrenergic Receptor,adrenergic,Beta Receptor,inhibit,hypothermia,receptor,Inhibitor,SR59230A,SR-59230A
CBNumber:
CB3331761
Molecular Formula:
C23H29NO6
Molecular Weight:
415.49
MDL Number:
MFCD06795851
MOL File:
174689-39-5.mol
MSDS File:
SDS
Last updated:2023-09-04 16:42:00
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1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Properties

storage temp. Inert atmosphere,Room Temperature
solubility DMSO: >10mg/mL
form powder
color white
FDA UNII Z4G2GB3YHU

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S8688 SR 59230A ≥98% (HPLC), powder 174689-39-5 5mg $165 2024-03-01 Buy
Sigma-Aldrich S8688 SR 59230A ≥98% (HPLC), powder 174689-39-5 25mg $228.4 2024-03-01 Buy
Tocris 1511 SR59230Ahydrochloride ≥98%(HPLC) 174689-39-5 10 $220 2021-12-16 Buy
Tocris 1511 SR59230Ahydrochloride ≥98%(HPLC) 174689-39-5 50 $926 2021-12-16 Buy
Usbiological 256751 SR 59230A hydrochloride 174689-39-5 10mg $466 2021-12-16 Buy
Product number Packaging Price Buy
S8688 5mg $165 Buy
S8688 25mg $228.4 Buy
1511 10 $220 Buy
1511 50 $926 Buy
256751 10mg $466 Buy

1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

SR 59230A was used in the identification of β-adrenoceptors in rat aorta.3 It was tested as a potential therapeutic agent in improving cardiac function in rat model of heart failure.4

Hazard

A poison.

Biological Activity

Potent and selective β 3 adrenoceptor antagonist (IC 50 values are 40, 408 and 648 nM for β 3 , β 1 and β 2 receptors respectively). Orally active in vivo . Also available as part of the β -Adrenoceptor Antagonist Tocriset™ .

Biochem/physiol Actions

SR 59230A is a β3-adrenoceptor antagonist. It has high affinity for the β3 adrenoceptors occurring in human gut that affect the function of human colonic circular smooth muscle.1 It is reported that SR 59230A inhibits the Kir2.1-2.3 cardiac potassium channels.2

1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Suppliers

Global( 54)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696，15000506266 15000506266 China 4121 55
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921 sales@pharmacodia.com China 2317 55
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 27322 60
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
InvivoChem 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Sigma-Aldrich 80
Shanghai Lollane Biological Technology Co.,Ltd. 55
Pharmacodia (Beijing) Co.,Ltd 55
Shanghai YuanYe Biotechnology Co., Ltd. 60

1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE Spectrum

1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE(174689-39-5)1HNMR

174689-39-5(1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE)Related Search:

(S)-N-METHYL-1,2,3,4-TETRAHYDRONAPHTHALEN-1-AMINE (S)--1-AMINOTETRALINE HCL 1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE (S)-(-)-1-BENZYLAMINO-3-PHENOXY-2-PROPANOL
SR 59230A HYDROCHLORIDE SR59230AHCl 3-(2-Ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphth-1-yl]amino]-(2S)-2-propanol oxalate salt SR 59230A 1-(2-ETHYLPHENOXY)-3-[[(1S)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL]AMINO]-(2S)-2-PROPANOL HYDROCHLORIDE (S)-1-(2-Ethylphenoxy)-3-(((S)-1,2,3,4-tetrahydronaphthalen-1-yl)amino)propan-2-ol oxalate SR 59230A >=98% (HPLC), powder 3-(2-ETHYLPHENOXY)-1-((1S)-1,2,3,4-TETRA-HYDRONAPHTH-1-YLAMINO)-(2S)-2-PROPANOL OXALATE hyperthermia,adrenoceptor,Adrenergic Receptor,adrenergic,Beta Receptor,inhibit,hypothermia,receptor,Inhibitor,SR59230A,SR-59230A 174689-39-5 C21H27NO2HCl Adrenoceptor