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Phlorizin dihydrate

CAS No.
7061-54-3
Chemical Name:
Phlorizin dihydrate
Synonyms
PHLORIDZIN;PHLORIDZIN(RG);Phlorizin dihydrate;TIMTEC-BB SBB005924;Phloridzin dihydrate 99%;phloridzin from apple wood;PHLORETIN-2'-BETA-D-GLUCOSIDE;Phlorizin dihydrate USP/EP/BP;Phloretin 2'-b-D-glucopyranoside;Phlorizin, Dihydrate, FroM Apple Wood
CBNumber:
CB3331802
Molecular Formula:
C21H26O11
Molecular Weight:
454.43
MDL Number:
MFCD00006591
MOL File:
7061-54-3.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

Phlorizin dihydrate Properties

Melting point 113-114 °C(lit.)
alpha -52 º (c=3, EtOH)
storage temp. Inert atmosphere,2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
optical activity [α]20/D 52°, c = 3 in ethanol
BRN 66621
CAS DataBase Reference 7061-54-3(CAS DataBase Reference)
FDA UNII CRK54BIJ5D

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  UC2080000
3-10-23

Phlorizin dihydrate price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 274313 Phloridzin dihydrate 99% 7061-54-3 1g $166 2024-03-01 Buy
Sigma-Aldrich 274313 Phloridzin dihydrate 97% 7061-54-3 5g $477 2024-03-01 Buy
Sigma-Aldrich P3449 Phloridzin dihydrate from apple wood, ≥99% (HPLC) 7061-54-3 100mg $58.2 2024-03-01 Buy
Sigma-Aldrich P3449 Phloridzin dihydrate from apple wood, ≥99% (HPLC) 7061-54-3 500mg $76.2 2024-03-01 Buy
Sigma-Aldrich P3449 Phloridzin dihydrate from apple wood, ≥99% (HPLC) 7061-54-3 1g $142 2024-03-01 Buy
Product number Packaging Price Buy
274313 1g $166 Buy
274313 5g $477 Buy
P3449 100mg $58.2 Buy
P3449 500mg $76.2 Buy
P3449 1g $142 Buy

Phlorizin dihydrate Chemical Properties,Uses,Production

Uses

Phloridzin dihydrate has been used as:

  • a Na+-glucose cotransport inhibitor to test its effect in lowering blood glucose
  • a hexose carrier inhibitor to prevent glucose derivative 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose (2-NBDG) uptake in sycamore cells
  • a non-specific sodium-glucose co-transporter 2 (SGLT2) inhibitor in embryonic cardiomyocyte cell line H9C2 to investigate its protective effect on Dox-induced cytotoxicity

Biochem/physiol Actions

Phloridzin is a glycoside present in the leaves and bark of apple. It is also present in peel and pulp of the apple fruit. Phloridzin belongs to the dihydrochalcones class of compounds. Lactase catabolizes phloridzin to phloretin and glucose in small intestine epithelial cells. Phloridzin is an antidiabetic agent and is equally bioavailable as phloretin.

target

NO | PGE | NOS | COX

Phlorizin dihydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 154)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 14936 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-519-519-85557386 marketing1@neostarunited.com China 8349 58
Zhengzhou Alfa Chemical Co.,Ltd
+8618530059196 sale04@alfachem.cn China 12321 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58

View Lastest Price from Phlorizin dihydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Phlorizin dihydrate pictures 2021-10-28 Phlorizin dihydrate
7061-54-3
US $10.00 / KG 100KG 99% 100 mt Hebei Guanlang Biotechnology Co., Ltd.
Phlorizin dihydrate pictures 2020-01-09 Phlorizin dihydrate
7061-54-3
US $1.00 / KG 1KG 98% HPLC 10 tons/month Career Henan Chemical Co
Phlorizin dihydrate 1-[2-(beta-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate 2'-O-GLUCOSYL-4',6',4-TRIHYDROXYDIHYDROCHALCONE 1-[2-(beta-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate TIMTEC-BB SBB005924 PHLORETIN-2'-BETA-D-GLUCOSIDE phloridzin from apple wood 1-[2-(β-d-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone PHLORIDZIN(RG) Phlorizin dihydrate Phloretin 2μ-β-D-glucopyranoside, Phloretin 2μ-β-D-glucoside, 1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone Phloridzin dihydrate,1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone, Phloretin 2′-β-D-glucopyranoside, Phloretin 2′-β-D-glucoside, Phlorizin dihydrate Phlorizin, Dihydrate, FroM Apple Wood Phloridzin dihydrate 99% Phloretin 2'-b-D-glucopyranoside 1-[2,4-dihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]phenyl]-3-(4-hydroxyphenyl)-1-propanone dihydrate 1-(2,4-Dihydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)-3-(4-hydroxyphenyl)propan-1-one dihydrate Phlorizin dihydrate USP/EP/BP 1-Propanone,1-[2-(b-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-,dihydrate PHLORIDZIN 7061-54-3 C21H24O10x2H2O C21H24O102H2O C21H28O12 Glycosides Sugars Carbohydrate Synthesis Biochemicals and Reagents Analytical Standards BioChemical Analytical Chromatography Product Catalog Natural Dyes Monosaccharides Specialty Synthesis Forensic and Veterinary Standards Drug Standards Chromatography Natural Plant Extract