ChemicalBook >> CAS DataBase List >>Delpazolid
Delpazolid
- CAS No.
- 1219707-39-7
- Chemical Name:
- Delpazolid
- Synonyms
- CS-2617;Delpazolid;LCB01-0371;Delpazolid (LCB01-0371);Antibiotic,Delpazolid,inhibit,Bacterial,Inhibitor;DELPAZOLID; LCB01-0371; LCB 01-0371; LCB-01-0371; LCB010371; LCB 010371; LCB-010371;(R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one;(5R)-3-[4-(5,6-Dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-2-oxazolidinone;2-Oxazolidinone, 3-[4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-, (5R)-;(5R)-3-[3-fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2, 4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazo lidin-2-one
- CBNumber:
- CB33357946
- Molecular Formula:
- C14H17FN4O3
- Molecular Weight:
- 308.31
- MDL Number:
- MFCD29918770
- MOL File:
- 1219707-39-7.mol
Last updated:2023-05-21 10:59:17
Boiling point | 481.8±55.0 °C(Predicted) |
---|---|
Density | 1.44±0.1 g/cm3(Predicted) |
storage temp. | Store at -20°C |
solubility | DMSO:30.0(Max Conc. mg/mL);97.3(Max Conc. mM) |
form | A crystalline solid |
pka | 14.05±0.10(Predicted) |
FDA UNII | 43EP6XV33E |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
Delpazolid price More Price(11)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 25532 | Delpazolid | 1219707-39-7 | 1mg | $44 | 2024-03-01 | Buy |
Cayman Chemical | 25532 | Delpazolid | 1219707-39-7 | 5mg | $193 | 2024-03-01 | Buy |
Cayman Chemical | 25532 | Delpazolid | 1219707-39-7 | 10mg | $341 | 2024-03-01 | Buy |
Cayman Chemical | 25532 | Delpazolid | 1219707-39-7 | 25mg | $745 | 2024-03-01 | Buy |
AK Scientific | 2814DF | Delpazolid | 1219707-39-7 | 25mg | $927 | 2021-12-16 | Buy |
Delpazolid Chemical Properties,Uses,Production
Description
Delpazolid is an oxazolidinone antibiotic. It is active against a wide range of Gram-positive bacterial clinical isolates, including resistant strains of several species, such as methicillin-resistant S. aureus (MRSA), methicillin-resistant coagulase-negative staphylococci (MRCNS), and penicillin-resistant S. pneumoniae (MICs = 0.125-4 μg/ml). Delpazolid increases survival in mouse models of systemic MRSA, E. faecalis, S. pneumoniae, and H. influenzae infection (ED50s = 2.96, 4.53, 2.28, and 9.96 mg/kg, respectively).
Synthesis of Delpazolid from ethyl (3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)carbamate(WXG00214) and (R)-Glycidyl butyrate
Delpazolid Preparation Products And Raw materials
Raw materials
ethyl (3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)carbamate(WXG00214)
2-fluoro-N-(2-(1-methylhydrazinyl)ethyl)-4-nitroaniline(WXG00212)
3-FLUORO-4-(1-METHYL-5,6-DIHYDRO-1H-[1,2,4]TRIAZIN-4-YL)-PHENYLAMINE(WXG00213)
1334167-59-7
4-(2-fluoro-4-nitrophenyl)-1-methyl-1,4,5,6-tetrahydro-1,2,4-triazine
1of2
Preparation Products
Global( 68)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9427 | 58 |
Guangzhou TongYi biochemistry technology Co.,LTD | +8613073028829 | mack@tongyon.com | China | 2996 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
Hefei fuya biotechnology co. LTD | 18096409024 | sales02@foreversyn.com | China | 1938 | 58 |
Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 |
View Lastest Price from Delpazolid manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2019-12-23 | Delpazolid
1219707-39-7
|
US $1.00 / g | 100g | 98%min | G/KG/T | Career Henan Chemical Co |
- Delpazolid
1219707-39-7
- US $1.00 / g
- 98%min
- Career Henan Chemical Co
Delpazolid
Delpazolid (LCB01-0371)
LCB01-0371
CS-2617
DELPAZOLID; LCB01-0371; LCB 01-0371; LCB-01-0371; LCB010371; LCB 010371; LCB-010371
(5R)-3-[4-(5,6-Dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-2-oxazolidinone
Delpazolid/(5R)-3-[4-(5,6-Dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-2-oxazolidinone
2-Oxazolidinone, 3-[4-(5,6-dihydro-1-methyl-1,2,4-triazin-4(1H)-yl)-3-fluorophenyl]-5-(hydroxymethyl)-, (5R)-
(R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one
(5R)-3-[3-fluoro-4-(1-methyl-1,4,5,6-tetrahydro-1,2,
4-triazin-4-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazo
lidin-2-one
Antibiotic,Delpazolid,inhibit,Bacterial,Inhibitor
1219707-39-7
C14H17FN4O3