Cyclo (-RGDfK) 2,2,2-Trifluoroacetic acid
- CAS No.
- 500577-51-5
- Chemical Name:
- Cyclo (-RGDfK) 2,2,2-Trifluoroacetic acid
- Synonyms
- Cyclo(-RGDfK) Trifluoroacetate;Cyclo(-RGDfK) TFA, 10 mM in DMSO;Cyclo (-RGDfK) 2,2,2-Trifluoroacetic acid;Cyclo(-Arg-Gly-Asp-D-Phe-Lys) trifluoroacetate;2-((2S,5R,8S,11S)-8-(4-Aminobutyl)-5-benzyl-11-(3-guanidinopropyl)-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentaazacyclopentadecan-2-yl)acetic acid Trifluoroacetate (1:1)
- CBNumber:
- CB33367651
- Molecular Formula:
- C29H42F3N9O9
- Molecular Weight:
- 717.6938896
- MDL Number:
- MOL File:
- 500577-51-5.mol
Cyclo (-RGDfK) 2,2,2-Trifluoroacetic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0102584 | Cyclo(-RGDfK)TFA 99.81% | 500577-51-5 | 5mg | $139 | 2021-12-16 | Buy |
| ChemScene | CS-0102584 | Cyclo(-RGDfK)TFA 99.81% | 500577-51-5 | 10mg | $216 | 2021-12-16 | Buy |
| AK Scientific | 1378EC | Cyclo(-RGDfK)2,2,2-Trifluoroaceticacid | 500577-51-5 | 50mg | $614 | 2021-12-16 | Buy |
| ChemScene | CS-0102584 | Cyclo(-RGDfK)TFA 99.81% | 500577-51-5 | 50mg | $660 | 2021-12-16 | Buy |
| Crysdot | CD00003792 | Cyclo(-RGDfK)2,2,2-Trifluoroaceticacid 98+% | 500577-51-5 | 100mg | $673 | 2021-12-16 | Buy |
Cyclo (-RGDfK) 2,2,2-Trifluoroacetic acid Chemical Properties,Uses,Production
Uses
Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM[1]. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface[3].
IC 50
αvβ3: 0.94 nM (IC50)
References
[1] Simecek J, et al. Benefits of NOPO as chelator in gallium-68 peptides, exemplified by preclinical characterization of (68)Ga-NOPO-c(RGDfK). Mol Pharm. 2014 May 5;11(5):1687-95. DOI:10.1021/mp5000746
[2] Lopez-Rodriguez V, et al. Preparation and preclinical evaluation of (66)Ga-DOTA-E(c(RGDfK))2 as a potential theranostic radiopharmaceutical. Nucl Med Biol. 2015 Feb;42(2):109-14. DOI:10.1016/j.nucmedbio.2014.09.010
Cyclo (-RGDfK) 2,2,2-Trifluoroacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Cyclo (-RGDfK) 2,2,2-Trifluoroacetic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32376 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38838 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20202 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
| Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5220 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Shanghai Chaolan Chemical Technology Center | 021-QQ：65489617 15618227136 | Sales@ATKchemical.com | China | 9364 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | Eric@peptidego.com | China | 7222 | 58 |
View Lastest Price from Cyclo (-RGDfK) 2,2,2-Trifluoroacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-25 | Cyclo(-RGDfK) TFA
500577-51-5
|
US $47.00-168.00 / mg | 99.54% | 10g | TargetMol Chemicals Inc. |
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- Cyclo(-RGDfK) TFA
500577-51-5
- US $47.00-168.00 / mg
- 99.54%
- TargetMol Chemicals Inc.
