ChemicalBook >> CAS DataBase List >>N,N,N',N'-Tetramethylazodicarboxamide
N,N,N',N'-Tetramethylazodicarboxamide
- CAS No.
- 10465-78-8
- Chemical Name:
- N,N,N',N'-Tetramethylazodicarboxamide
- Synonyms
- TMAD;DIAMIDE;Tetramethylazodicarboxamide;N1,N1,N2,N2-Tetramethyldiazene-1,2-dicarboxamide;(3E)-3-(dimethylcarbamoylimino)-1,1-dimethyl-urea;(E)-1-[(dimethylcarbamoyl)imino]-3,3-dimethylurea;Nsc143013;Diamide ,98%;Diamide, 98%, for synthesis;Azobis(N,N-dimethylformamide)
- CBNumber:
- CB3340747
- Molecular Formula:
- C6H12N4O2
- Molecular Weight:
- 172.19
- MDL Number:
- MFCD00008318
- MOL File:
- 10465-78-8.mol
Last updated:2023-08-01 10:15:29
| Melting point | 112 °C |
|---|---|
| Boiling point | 220.4±23.0 °C(Predicted) |
| Density | 1.13±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | soluble in Methanol |
| form | crystalline |
| pka | -0?+-.0.70(Predicted) |
| color | yellow |
| BRN | 1910409 |
| InChI | InChI=1S/C6H12N4O2/c1-9(2)5(11)7-8-6(12)10(3)4/h1-4H3/b8-7+ |
| InChIKey | VLSDXINSOMDCBK-BQYQJAHWSA-N |
| SMILES | C(=O)(/N=N/C(=O)N(C)C)N(C)C |
| CAS DataBase Reference | 10465-78-8(CAS DataBase Reference) |
| FDA UNII | 86EQC90W32 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| RTECS | LQ1041000 |
| F | 4.10 |
| HS Code | 29270000 |
N,N,N',N'-Tetramethylazodicarboxamide price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | D3648 | Diamide | 10465-78-8 | 1g | $143 | 2024-03-01 | Buy |
| Sigma-Aldrich | D3648 | Diamide | 10465-78-8 | 5g | $629 | 2024-03-01 | Buy |
| TCI Chemical | A1458 | 1,1'-Azobis(N,N-dimethylformamide) >97.0%(T) | 10465-78-8 | 1g | $23 | 2024-03-01 | Buy |
| TCI Chemical | A1458 | 1,1'-Azobis(N,N-dimethylformamide) >97.0%(T) | 10465-78-8 | 5g | $84 | 2024-03-01 | Buy |
| Alfa Aesar | J64865 | 1,1'-Azobis(N,N-dimethylformamide), 95% | 10465-78-8 | 1g | $140 | 2024-03-01 | Buy |
N,N,N',N'-Tetramethylazodicarboxamide Chemical Properties,Uses,Production
Description
N,N,N’,N’-Tetramethylazodicarboxamide (also named as Diamide, TMAD) is a reagent used for the oxidization of thiols in proteins. It is used as a reagent in the Mitsunobu reaction in place of diethyl azodicarboxylate. It can be used to titrate protein gluotathiolation to discriminate from other protein modifications.
References
N. S. Kosower, E. M. Kosower, Diamide: A oxidant probe for this, Methods in Enzymology, 1995, vol. 251, pp. 123133
Chemical Properties
Yellow crystals
Uses
Reported to be of use as a thiol oxidizing agent. Diamide has been used to titrate protein glutathiolation to discriminate from other oxidative protein modifications. Treatment increased protein glutathiolation in a concentration-dependent manner and had comparably little effect on protein-protein disulfide formation.
Definition
ChEBI: 1,1'-azobis(N,N-dimethylformamide) is a monoazo compound.
Synthesis Reference(s)
The Journal of Organic Chemistry, 38, p. 1652, 1973 DOI: 10.1021/jo00949a007
N,N,N',N'-Tetramethylazodicarboxamide Preparation Products And Raw materials
Global( 185)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing New Thinking Chem Co.,Ltd | +8615896017193 | nanjingxinsi@163.com | China | 217 | 58 |
| Suzhou BEC Biological Technology Co., Ltd. | +undefined13771885869 | all@bek.com.cn | China | 62 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 6992 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
View Lastest Price from N,N,N',N'-Tetramethylazodicarboxamide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | N,N,N',N'-Tetramethylazodicarboxamide
10465-78-8
|
US $1.00 / KG | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- N,N,N',N'-Tetramethylazodicarboxamide
10465-78-8
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
10465-78-8(N,N,N',N'-Tetramethylazodicarboxamide)Related Search:
Tetramethylazodicarboxamide(TMAD)
1,1μ-Azobis(N,N-dimethylformamide), Azodicarboxylic acid bis(dimethylamide), Diazinedicarboxylic acid bis(N,N-dimethylamide), N,N,Nμ,Nμ-Tetramethylazodicarboxamide
Azodicarboxylic acid bis(dimethylamide), diamide, Diamide, Diazinedicarboxylic acid bis(N,N-dimethylamide), N,N,Nμ,Nμ-Tetramethylazodicarboxamide
1,1′-Azobis(N,N-dimethylformamide), Azodicarboxylic acid bis(dimethylamide)
Diazenedicarboxylic acid bis(N,N-dimethylamide)
Formamide, 1,1'-azobis[N,N-dimethyl-
AZODICARBOXYLIC ACID BIS[DIMETHYLAMIDE]
DIAZINE-DICARBOXYLIC ACID BIS[N,N-DIMETHYLAMIDE]
1,1'-AZOBIS(N,N'-DIMETHYLFORMAMIDE)
1,1'-AZOBIS(N,N-DIMETHYLFORMAMIDE)
N,N,N',N'-TETRAMETHYLAZODICARBAMIDE
N,N,N',N'-TETRAMETHYLAZODICARBOXAMIDE
1,1’-azobis(n,n-dimethyl-formamid
n,n,n’,n’-tetramethylazoformamide
Diamide
N,N,N',N'-Tetramethylazodicarboxamide
Azodicarboxylic acid bis(dimethylamide), diamide
TMAD N,N,N',N'-tetramethylazodicarboxamide
1,1'-Azobis(N,N-dimethylformamide)≥ 98%(Titration)
N,N,N',N'-Tetramethylazobisformamide
Nsc143013
N,N,N',N'-Tetramethylazodicarboxamide(TMAD)
Diamide ,98%
1-[(diMethylcarbaMoyl)iMino]-3,3-diMethylurea
tetramethyl-diazenedicarboxamid
tetramethyldiazenedicarboxamide
1,1-Azobis(N,N-dimethylforamide)
3-(N,N-dimethylcarbamoylimido)-1,1-dimethylurea
Diamide 1,1-Azobis(N,N-dimethylformamide)
blowing (and foaming) agent AC
3-(Dimethylcarbamoylimino)-1,1-dimethylurea
Diazenedicarboxamide, tetramethyl-
Azobis(N,N-dimethylformamide)
N,N,N',N'-Tetramethyldiazene-1,2-dicarboxamide
N,N,N',N'-Tetramethyldiazenedicarboxamide
1,1'-Azobis(N,N-dimethylformamide),98%
1,1'-Azobis(N,N-dimethylformamide) >
Diamide, 98%, for synthesis
1,2-Diazenedicarboxamide, N1,N1,N2,N2-tetramethyl-
N,N,N',N'-Tetramethylazodicarboxamide ISO 9001：2015 REACH
TIANFU-CHEM CAS:10465-78-8 N,N,N',N'-Tetramethylazodicarboxamide
(3E)-3-(dimethylcarbamoylimino)-1,1-dimethyl-urea
DIAMIDE
N1,N1,N2,N2-Tetramethyldiazene-1,2-dicarboxamide
Tetramethylazodicarboxamide
TMAD
(E)-1-[(dimethylcarbamoyl)imino]-3,3-dimethylurea
(E)-N1,N1,N2,N2-tetramethyldiazene-1,2-dicarboxamide
N,N,N',N'-Tetramethylazodicarboxamide
10465-78-8
CH32NCONNCONCH32
Amides
BioChemical
Building Blocks
Biochemicals and Reagents
Carbonyl Compounds
Glyceraldehyde 3-Phosphate Dehydrogenase from a green algae
Enzymes, Inhibitors, and Substrates
Enzyme Inhibitors by Enzyme