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2-Chloroethylamine hydrochloride

2-Chloroethylamine hydrochloride Structure
2-Chloroethylamine hydrochloride structure
CAS No.
870-24-6
Chemical Name:
2-Chloroethylamine hydrochloride
Synonyms
CHLOROETHYLAMINE HYDROCHLORIDE;2-Chloroethylamine;2-CHLOROETHYLAMINE HCL;2-ChloroethylamineHcl99%;2-Chloroethylamine h;BETA-CHLOROETHYLAMINE;2-CHLOROPROPYLAMINE·HCL;Ifosfamide EP impurity C;2-Chlorethylammoniumchlorid;Ifosfamide EP Impurity C HCl
CBNumber:
CB3348187
Molecular Formula:
C2H7Cl2N
Molecular Weight:
115.99
MDL Number:
MFCD00012887
MOL File:
870-24-6.mol
Last updated:2025-09-25 17:15:13
Product description Number Pack Size Price
2-Chloroethylammonium chloride for synthesis 8.20265 100g $57.4
2-Chloroethylammonium chloride for synthesis 8.20265 250g $90.3
2-Chloroethylamine hydrochloride purum, ≥98.0% (AT) 23035 100g $73.2
2-Chloroethylamine hydrochloride purum, ≥98.0% (AT) 23035 5g $25
2-Chloroethylamine Hydrochloride >98.0%(N)(T) C0851 25g $24
More product size
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2-Chloroethylamine hydrochloride Properties

Melting point 140-150 °C(lit.)
bulk density 750-850kg/m3
storage temp. Store below +30°C.
solubility 5666g/l
form Crystalline Powder
color White to light beige
PH 2-3 (5666g/l, H2O, 20℃)
Water Solubility SOLUBLE
Sensitive Hygroscopic
BRN 3590304
InChI InChI=1S/C2H6ClN.ClH/c3-1-2-4;/h1-2,4H2;1H
InChIKey ONRREFWJTRBDRA-UHFFFAOYSA-N
SMILES NCCCl.[H]Cl
CAS DataBase Reference 870-24-6(CAS DataBase Reference)
FDA UNII 8040U3I02T
EPA Substance Registry System 2-Chloroethylamine hydrochloride (870-24-6)
UNSPSC Code 12352107
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS08
Signal word  Danger
Hazard statements  H290-H314-H341
Precautionary statements  P202-P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  Xi,C
Risk Statements  36/37/38-68-34
Safety Statements  26-36-37/39-45-36/37/39
RIDADR  UN3261
WGK Germany  3
RTECS  KR1800000
F  3-10-34
TSCA  Yes
HazardClass  8
PackingGroup  III
HS Code  29211980
Toxicity LD50 orally in Rabbit: > 2000 mg/kg
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
0
2 0

2-Chloroethylamine hydrochloride price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.20265 2-Chloroethylammonium chloride for synthesis 870-24-6 100g $57.4 2025-07-31 Buy
Sigma-Aldrich 8.20265 2-Chloroethylammonium chloride for synthesis 870-24-6 250g $90.3 2025-07-31 Buy
Sigma-Aldrich 23035 2-Chloroethylamine hydrochloride purum, ≥98.0% (AT) 870-24-6 100g $73.2 2025-07-31 Buy
Sigma-Aldrich 23035 2-Chloroethylamine hydrochloride purum, ≥98.0% (AT) 870-24-6 5g $25 2023-06-20 Buy
TCI Chemical C0851 2-Chloroethylamine Hydrochloride >98.0%(N)(T) 870-24-6 25g $24 2025-07-31 Buy
Product number Packaging Price Buy
8.20265 100g $57.4 Buy
8.20265 250g $90.3 Buy
23035 100g $73.2 Buy
23035 5g $25 Buy
C0851 25g $24 Buy

2-Chloroethylamine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

2-Chloroethylamine hydrochloride (C2H7Cl2N, CAS registry No. 870-24-6) is a white to light beige crystalline powder. It is soluble in water and stable at room temperature in closed containers under normal storage and handling conditions. It should store in a tightly closed container, in a cool, dry, well-ventilated area away from incompatible substances and should be protected from moisture.

Application

2-Chloroethylamine hydrochloride is an important fine chemical intermediate. It can be used for the synthesis of fluvoxamine maleate, which is an important antidepressant drug. 2-Chloroethylamine hydrochloride can also be used as the substrate to synthesize 2-(2'-Aminoaryl)oxazolines and their derivatives, which have been studied as ligands for a variety of metal chelates and are known to possess biological activity in both free ligand and chelated forms. Meanwhile, 2-chloroethylamine hydrochloride can be used for chemical modification of chitosan to improve the biological activity of chitosan.
2-Chloroethylamine hydrochloride can also react with hydroxypropyl starch (HPS) to form aminoethyl hydroxypropyl starch (AEHPS), which can react with collagen peptide (COP) by using microbial transglutaminase (MTGase) as biocatalyst to synthesize aminoethyl hydroxypropyl starch collagen peptide (AEHPS-COP). The AEHPS-COP showed a promising potential application in cosmetic, biomedical and pharmaceutical fields with improved in vitro antioxidant activities.

Chemical Properties

WHITE TO LIGHT BEIGE CRYSTALLINE POWDER

Uses

2-Chloroethylamine hydrochloride can be used in the preparation of novel Schiff base ligands. These ligands, when immobilized on silica gels, form inexpensive materials for the removal of metal ions such as Ni2+ and Co2+ ions from contaminated water.
Other applications:

  • Alginate derivatization via aminoethylation to form aminoethyl alginate.
  • Synthesis of N-(2-chloroethyl)-benzaldimine.
  • Derivatization of starch to form aminoethyl (AE-St) starch derivatives.

Uses

2-chloroethylamine hydrochloride is used as an intermediate in active pharmaceutical ingredients and dyes. It is also used in organic synthesis. Further, it is employed as a derivatizing reagent for amino acids, dipeptides and nucleotides.

Synthesis

ETHANOLAMINE HYDROCHLORIDE

2002-24-6

2-Chloroethylamine hydrochloride

870-24-6

Example 7: 975 g of monoethanolamine hydrochloride, 3.7 g of dimethylformamide and 3500 g of benzene were mixed and heated to 75°C to 80°C. Subsequently, 1404 g of thionyl chloride was slowly added dropwise to the reaction mixture over 7 hours at the same temperature. After the dropwise addition was completed, the reaction was continued by keeping the reaction solution at the same temperature for 1 hour. Upon completion of the reaction, the mixture was cooled to 30°C and then 2900 g of water was added. After standing, the solution separated into a benzene layer and an aqueous layer. 4150 g of the aqueous layer was collected, which contained 2-chloroethylamine hydrochloride in 98% yield. The content of free sulfur dioxide in the aqueous layer was 2.7% by weight.

References

[1] Bulletin des Societes Chimiques Belges, 1984, vol. 93, # 10, p. 903 - 912
[2] Patent: US3956385, 1976, A
[3] Patent: CN105585607, 2016, A. Location in patent: Paragraph 0111; 0112; 0113; 0114
[4] Journal of Organic Chemistry, 1944, vol. 9, p. 137
[5] Journal of the American Chemical Society, 1935, vol. 57, p. 916

2-Chloroethylamine hydrochloride Preparation Products And Raw materials

Raw materials

Monoethanolamine ETHANOLAMINE HYDROCHLORIDE Benzene Thionyl chloride N-Methylacetamide
Water

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Preparation Products

N-Aminoethylpiperazine 2-Phenoxyethylamine Taurine 2-Imidazol-1-ylethanamine 2-Chloroethyl isocyanate
Imidazo[1,2-b]pyridazine 2-CHLOROETHYL ISOTHIOCYANATE selenocystamine Pyridine, 2-(4,5-dihydro-2-oxazolyl)- (9CI) N-METHYLETHYLENEDIAMINE
2-(propylthio)ethanamine(SALTDATA: HCl) N-(2-Chloroethyl)-3-methoxybenzamide (2-Chloroethyl)sulfaMoyl Chloride 2-(2-methyl-imidazol-1-yl)-ethylamine hydrobromide (2-CHLOROETHYL)-4-FLUOROBENZAMIDE

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2-Chloroethylamine hydrochloride Suppliers

Global( 604)Suppliers
Supplier Tel Email Country ProdList Advantage
TOKYO CHEMICAL INDUSTRY CO., LTD.
03-36680489 Sales-JP@TCIchemicals.com Japan 28387 80
Hebei Yanxi Chemical Co., Ltd. 		+8618531123677 faithe@yan-xi.com China 5853 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615531151365 mina@chuanghaibio.com China 18126 58
Hebei Zhuanglai Chemical Trading Co Ltd 		+86-16264648883 niki@zlchemi.com China 7245 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21615 55
Shanghai Time Chemicals CO., Ltd. 		+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1803 55
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29850 58
Zhejiang ZETian Fine Chemicals Co. LTD 		+8618957127338 stella@zetchem.com China 2161 58
Supplier Advantage
TOKYO CHEMICAL INDUSTRY CO., LTD.
80
Hebei Yanxi Chemical Co., Ltd. 		58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Zhuanglai Chemical Trading Co Ltd 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Shanghai Time Chemicals CO., Ltd. 		55
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Zhejiang ZETian Fine Chemicals Co. LTD 		58

Related articles

View Lastest Price from 2-Chloroethylamine hydrochloride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloroethylamine hydrochloride pictures 2025-11-14 2-Chloroethylamine hydrochloride
870-24-6
 0.99 RongNa Biotechnology Co.,Ltd
2-Chloroethylamine hydrochloride pictures 2025-11-14 2-Chloroethylamine hydrochloride
870-24-6
 US $0.00 / Kg/Drum 1KG 99%min 500kg WUHAN FORTUNA CHEMICAL CO., LTD
2-Chloroethylamine hydrochloride pictures 2025-08-08 2-Chloroethylamine hydrochloride
870-24-6
 US $50.00 / KG 1KG 99% 5000KG Sichuan Zhuoyu Yantang Technology Co., Ltd.

2-Chloroethylamine hydrochloride Spectrum

2-Chloroethylamine hydrochloride(870-24-6)MS2-Chloroethylamine hydrochloride(870-24-6)1HNMR2-Chloroethylamine hydrochloride(870-24-6)13CNMR2-Chloroethylamine hydrochloride(870-24-6)IR12-Chloroethylamine hydrochloride(870-24-6)IR22-Chloroethylamine hydrochloride(870-24-6)IR32-Chloroethylamine hydrochloride(870-24-6)Raman

870-24-6(2-Chloroethylamine hydrochloride)Related Search:

Calcium chloride Topotecan hydrochloride Diethylamine hydrochloride Ethylamine hydrochloride Choline chloride
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Ammonium chloride 3-(2-Chloroactyl)-2-[(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide 3-Chloro-N-(2-chloroethyl)-1-propanamine hydrochloride Potassium chloride 3-(3-Hydroxypropyl)-2-oxazolidinone
Ifosfamide impurity A Monoethanolamine Ifosfamide

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2-CHLOROETHYLAMINE MONOHYDROCHLORIDE, 99 % 2-CHLOROPROPYLAMINE·HCL 2-ChloroethylamineHydrochloride98% 2-CHLOROETHYLAMINE HYDROCHLORIDE (CEA) 2-CHLOROETHYLAMINE HYDROCHLORIDE (70% SOLUTION) (CEA LIQ) 2-Chloroethylamine hydrochloride, 70 wt.% aqueous solution 2-CHLOROETHYLAMINE MONOHYDROCHLORIDE 2-CHLOROETHYLAMINO HYDROCHLORIDE 2-CHLOROETHYLAMMONIUM CHLORIDE 2-CHLOROETHYLAMINE HYDROCHLORIDE 2-AMINOETHYL CHLORIDE HYDROCHLORIDE 2-chloro-ethanaminhydrochloride 2-chloro-ethylaminhydrochloride Ethanamine,2-chloro-,hydrochloride 2-Chloroethylamine HCl anhyd. B-ChloroethylamineHydrochloride 2-Chloroethylamine hydrochloride 98% 2-CHLOROETHANAMINEHYDROCHLORIDE BETA-CHLOROETHYLAMINE 2-Chloroethylazanium chloride 2-Chloroethylamine hydrochloride ,99% 2-Chloroethylamine h 2-Chloro ethyl aMine hydrochloride aquous solution 2-ChloroethylaMine hydrochloride, 98% 100GR 2-ChloroethylaMine hydrochloride puruM, >=98.0% (AT) 2 - chloro riMantadine hydrochloride 1-amino-2-chloroethane hydrochloride 2-Chloroethylamine hydrochloride≥ 99% (Assay) 2-Aminoethyl chloride hydrochloride, 70% Wt aqueous solution 2-Chloroethylamine hydrochloride, 70% Wt aqueous solution≥ 70% (Titration) 2-Chloroethylammonium chloride for synthesis BETA-AMINOETHYL CHLORIDE HYDROCHLORIDE BETA-CHLOROETHYLAMINE HYDROCHLORIDE Ifosfamide EP impurity C 5-fluoro-5-(trifluoromethyl)-1-cyclohexa-1,3-dienecarboxaldehyde Trazodone impurity SM-4-Z2 hydrochloride 2-Chloroethylamine Hydrochloride > 2-CHLOROETHYLAMMONIUM CHLORIDE FOR SYNTH Trazodone Impurity SM-4-Z2 HCl Ifosfamide EP Impurity C HCl Ifosfamide Impurity 3（Ifosfamide EP Impurity C HCl） 2-CHLOROETHYLAMINE HYDROCHLORIDE 870-24-6 2-Chloroethylamine hydrochloride ISO 9001：2015 REACH 2-Chlorethylammoniumchlorid 2-ChloroethylamineHcl99% 2-CHLOROETHYLAMINE HCL 2-Chloroethylamine CHLOROETHYLAMINE HYDROCHLORIDE 2-chlorethylamine hydrochloride Caprylic Acid Impurity 17-d12 2-Chloroethylamine hydrochloride, 70% Ifosfamide im.C(EP) as HCl Salt: 2-chloroethanamine hydrochloride 870-24-6 C2H7NCl2 C2H6ClNxHCl C2H6ClNHCl C2H7Cl2N ClCH2CH2NH2HCl