22(R)-HYDROXYCHOLESTEROL
- CAS No.
- 17954-98-2
- Chemical Name:
- 22(R)-HYDROXYCHOLESTEROL
- Synonyms
- 22R-OHC;22(R)-OH-CH;Narthesterol;22α-hydroxycholesterol;22BF-HYDROXYCHOLESTEROL;Cholesterol 22α-Hydroxy;22α-Hydroxy Cholesterol;22(R)-Hydroxycholestero;Chlorambucil Impurity 8;22(R)-HYDROXYCHOLESTEROL
- CBNumber:
- CB3350290
- Molecular Formula:
- C27H46O2
- Molecular Weight:
- 402.65
- MDL Number:
- MFCD00070042
- MOL File:
- 17954-98-2.mol
- MSDS File:
- SDS
| Melting point | 171-174°C |
|---|---|
| Boiling point | 513.1±23.0 °C(Predicted) |
| Density | 1.03±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 15.01±0.20(Predicted) |
| color | White to Off-White |
| InChIKey | RZPAXNJLEKLXNO-QUOSNDFLSA-N |
22(R)-HYDROXYCHOLESTEROL price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H9384 | 22(R)-Hydroxycholesterol ≥98% | 17954-98-2 | 1mg | $110 | 2024-03-01 | Buy |
| Sigma-Aldrich | H9384 | 22(R)-Hydroxycholesterol ≥98% | 17954-98-2 | 5mg | $418 | 2024-03-01 | Buy |
| Cayman Chemical | 89355 | 22(R)-hydroxy Cholesterol ≥98% | 17954-98-2 | 1mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 89355 | 22(R)-hydroxy Cholesterol ≥98% | 17954-98-2 | 5mg | $264 | 2024-03-01 | Buy |
| Cayman Chemical | 89355 | 22(R)-hydroxy Cholesterol ≥98% | 17954-98-2 | 10mg | $468 | 2024-03-01 | Buy |
22(R)-HYDROXYCHOLESTEROL Chemical Properties,Uses,Production
Description
The liver X receptors (LXRα and LXRβ) are nuclear hormone receptors whose native ligands are oxysterols. LXRs regulate the oxysterol-
Uses
The 22R-metabolite of Cholesterol (C432501). 22-Hydroxycholesterol inhibits chemokine receptor activity.
Uses
Bovine aortic endothelial cells were treated with 22(R)-Hydroxycholesterol to study the effects on production of free radicals and in studies related to fatty acid metabolism.
Definition
ChEBI: An oxysterol that is the 22R-hydroxy derivative of cholesterol.
General Description
22(R)-hydroxycholesterol is a diastereomer of 22(S)-hydroxycholesterol. It is present in neonate brain.
Biochem/physiol Actions
22(R)-hydroxycholesterol (22(R)-HC) is a liver X receptor (LXR) ligand.. 22(R)-HC in combination with other oxysterols promote mesenchymal stem cell osteogenesis. It regulates cholesterol homeostasis. Low levels of 22(R)-HC is observed in Alzheimer′s disease and it may be implicated in neuroinflammation and neurodegenerative diseases. 22(R)-hydroxycholesterol also suppresses prostate tumor progression.
22(R)-HYDROXYCHOLESTEROL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15371 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Henan Aochuang Chemical Co.,Ltd. | +86-0371-63689365 +8618638391208 | sales@aochuangchem.com | China | 9425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2210 | 55 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@163.com | China | 284 | 58 |
View Lastest Price from 22(R)-HYDROXYCHOLESTEROL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-10-20 | 22(R)-HYDROXYCHOLESTEROL
17954-98-2
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. |
-
- 22(R)-HYDROXYCHOLESTEROL
17954-98-2
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
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