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ChemicalBook >> CAS DataBase List >>N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide

N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide

N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide Structure
N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide structure
CAS No.
296771-07-8
Chemical Name:
N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide
Synonyms
dCeMM2;2-((5H-[1,2,4]Triazino[5,6-b]indol-3-yl)thio)-N-(5-chloropyridin-2-yl)acetamide;Acetamide, N-(5-chloro-2-pyridinyl)-2-(5H-1,2,4-triazino[5,6-b]indol-3-ylthio)-;N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide
CBNumber:
CB33512710
Molecular Formula:
C16H11ClN6OS
Molecular Weight:
370.81614
MDL Number:
MOL File:
296771-07-8.mol
Last updated:2023-06-30 15:45:59
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N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide Properties

Density 1.60±0.1 g/cm3(Predicted)
solubility Soluble to 50 mM in DMSO
pka 10.25±0.50(Predicted)

N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Axon Medchem Axon3293 dCeMM2 99% 296771-07-8 10mg $104.5 2021-12-16 Buy
Axon Medchem Axon3293 dCeMM2 99% 296771-07-8 50mg $418 2021-12-16 Buy
Product number Packaging Price Buy
Axon3293 10mg $104.5 Buy
Axon3293 50mg $418 Buy

N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide Chemical Properties,Uses,Production

Biological Activity

dCeMM2 is a molecular glue degrader. Induces ubiquitination and degradation of cyclin K by eliciting an interaction of CDK12-cyclin K with a CRL4B ligase complex. dCeMM2 displays near-total degradation of protein at 2.5 μM within 2h. Cell-permeable.

storage

Store at -20°C

N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Nantong HI-FUTURE Biology Co., Ltd. 		+undefined18051384581 sales@chemhifuture.com China 3136 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3501 55
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1350 58
Nantong Hi-Future Biotechnology Co., Ltd 18051384581 sales@chemhifuture.com China 3061 58
Bide Pharmatech Ltd. 400-1647117 15221909166 product02@bidepharm.com China 63720 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24018 58
Aikon International Limited 18626450290 yftan@aikonchem.com China 10718 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Nantong HI-FUTURE Biology Co., Ltd. 		58
Aladdin Scientific 		58
Shanghai EFE Biological Technology Co., Ltd. 58
Tianjin Kailiqi Biotechnology Co., Ltd. 55
Jilin Province Woda Biotechnology Co., Ltd. 58
Nantong Hi-Future Biotechnology Co., Ltd 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58
Aikon International Limited 58
N-(5-chloropyridin-2-yl)-2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylsulfanyl)acetamide dCeMM2 Acetamide, N-(5-chloro-2-pyridinyl)-2-(5H-1,2,4-triazino[5,6-b]indol-3-ylthio)- 2-((5H-[1,2,4]Triazino[5,6-b]indol-3-yl)thio)-N-(5-chloropyridin-2-yl)acetamide 296771-07-8