ChemicalBook >> CAS DataBase List >>CGS 15943
CGS 15943
- CAS No.
- 104615-18-1
- Chemical Name:
- CGS 15943
- Synonyms
- CGS 15943;CGS-15943A;CGS-15943 solid;CGS-15943 ADENOSINE A1 RECEPTOR;9-CHLORO-2-(2-FURYL)(1,2,4)TRIAZOLO(1,5-C)QUINAZOLIN-5-AMINE;9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine;9-CHLORO-2-(2-FURANYL)-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE;9-Chloro-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine;[1,2,4]Triazolo[1,5-c]quinazolin-5-amine,9-chloro-2-(2-furanyl)-;9-Chloro-5,6-dihydro-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-imine
- CBNumber:
- CB3351424
- Molecular Formula:
- C13H8ClN5O
- Molecular Weight:
- 285.69
- MDL Number:
- MFCD01529897
- MOL File:
- 104615-18-1.mol
Last updated:2023-09-20 16:43:00
| Melting point | 278-279 °C |
|---|---|
| Density | 1.72±0.1 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO: >16 mg/mL |
| pka | 1.23±0.30(Predicted) |
| form | solid |
| color | white |
| FDA UNII | Y5A5D5E2AQ |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
| WGK Germany | 3 |
CGS 15943 price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C199 | CGS-15943 solid | 104615-18-1 | 25mg | $160 | 2024-03-01 | Buy |
| Alfa Aesar | J61313 | CGS 15943, 99+% | 104615-18-1 | 10mg | $94.8 | 2021-12-16 | Buy |
| Alfa Aesar | J61313 | CGS 15943, 99+% | 104615-18-1 | 50mg | $327 | 2021-12-16 | Buy |
| Cayman Chemical | 22073 | CGS 15943 ≥95% | 104615-18-1 | 5mg | $33 | 2024-03-01 | Buy |
| Cayman Chemical | 22073 | CGS 15943 ≥95% | 104615-18-1 | 10mg | $62 | 2024-03-01 | Buy |
CGS 15943 Chemical Properties,Uses,Production
Uses
Potent adenosine receptor antagonist
Definition
ChEBI: A member of the class of triazoloquinazolines that is [1,2,4]triazolo[1,5-c]quinazoline substited at positions 2, 5 and 9 by furan-2-yl, amino and chloro groups respectively. A potent antagonist at adenosine A1 and adenosi e A2A receptors.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 27, p. 1549, 1990 DOI: 10.1002/jhet.5570270605
Biological Activity
Potent adenosine receptor antagonist (K i values are 3.5, 4.2, 16 and 51 nM for human A 1 , A 2A , A 2B and A 3 receptors respectively). Orally active in vivo .
Biochem/physiol Actions
CGS-15943 is a potent and non-selective adenosine receptor antagonist. It exhibits anti-carcinogenic and anti-apoptotic activity.
storage
Store at RT
CGS 15943 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 75)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou PBpharmaceutical R&D Co.,Ltd | 0519-83990708 | info@pbpharm.com | CHINA | 498 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2784 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
104615-18-1(CGS 15943)Related Search:
CGS 15943
9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine
9-Chloro-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-amine
9-Chloro-5,6-dihydro-2-(furan-2-yl)[1,2,4]triazolo[1,5-c]quinazolin-5-imine
CGS-15943A
9-CHLORO-2-(2-FURYL)(1,2,4)TRIAZOLO(1,5-C)QUINAZOLIN-5-AMINE
9-CHLORO-2-(2-FURANYL)-[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINE
CGS-15943 ADENOSINE A1 RECEPTOR
[1,2,4]Triazolo[1,5-c]quinazolin-5-amine,9-chloro-2-(2-furanyl)-
CGS-15943 solid
Adenosine Receptor,CGS-15943,Phosphoinositide 3-kinase,P1 receptor,PI3K,inhibit,CGS15943,CGS 15943,Inhibitor
104615-18-1
C13H8ClN5O
Adenosine receptor