ChemicalBook >> CAS DataBase List >>Methyl 4-oxotetrahydrothiophene-3-carboxylate

Methyl 4-oxotetrahydrothiophene-3-carboxylate

CAS No.
2689-68-1
Chemical Name:
Methyl 4-oxotetrahydrothiophene-3-carboxylate
Synonyms
AKOS 92615;methyl tetrahydro-4-oxo-3-thenoate;4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENE;4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENONE;3-Carbomethoxytetrahydrothiophene-4-one;METHYL 3-OXOTETRAHYDROTHIOPHENE4-CARBOXYLATE;METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE;Methyl 4-oxotetrahydrothiophene-3-carboxylate ,97%;Methyl 4-oxotetrahydrothiophene-3-carboxylate, 95+%;tetrahydro-4-oxo-3-thiophenecarboxylicacimethylester
CBNumber:
CB3354748
Molecular Formula:
C6H8O3S
Molecular Weight:
160.19
MDL Number:
MFCD00052381
MOL File:
2689-68-1.mol
Last updated:2023-05-16 17:00:21

Methyl 4-oxotetrahydrothiophene-3-carboxylate Properties

Melting point 37-38 °C
Boiling point 95 °C
Density 1.309±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility Chloroform
form Solid
pka 10.52±0.20(Predicted)
color Light Yellow
InChI InChI=1S/C6H8O3S/c1-9-6(8)4-2-10-3-5(4)7/h4H,2-3H2,1H3
InChIKey LEAKUJFYXNILRB-UHFFFAOYSA-N
SMILES C1SCC(=O)C1C(OC)=O
EPA Substance Registry System 3-Thiophenecarboxylic acid, tetrahydro-4-oxo-, methyl ester (2689-68-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302+H312+H332-H315-H319-H335
Precautionary statements  P271-P280
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
HazardClass  IRRITANT
HS Code  29339900

Methyl 4-oxotetrahydrothiophene-3-carboxylate price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T294170 Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster 2689-68-1 5G $440 2021-12-16 Buy
TRC T294170 Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster 2689-68-1 25g $1650 2021-12-16 Buy
American Custom Chemicals Corporation CHM0030710 METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE 95.00% 2689-68-1 10G $1320.38 2021-12-16 Buy
American Custom Chemicals Corporation CHM0030710 METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE 95.00% 2689-68-1 1G $631.34 2021-12-16 Buy
Medical Isotopes, Inc. 67223 Tetrahydro-4-oxo-3-thiophenecarboxylicAcidMethylEster 2689-68-1 500mg $650 2021-12-16 Buy
Product number Packaging Price Buy
T294170 5G $440 Buy
T294170 25g $1650 Buy
CHM0030710 10G $1320.38 Buy
CHM0030710 1G $631.34 Buy
67223 500mg $650 Buy

Methyl 4-oxotetrahydrothiophene-3-carboxylate Chemical Properties,Uses,Production

Chemical Properties

White solid

Uses

Methyl 4-oxotetrahydrothiophene-3-carboxylate is used in the preparation of a new class of neuroleptic agents.

Synthesis

2,3,4,5-Tetrahydro-4-oxo-3-thiophene carboxylic acid, methyl ester (L75a): 25.3 g (1.1 mol) of sodium were implemented in 190 mL abs. methanol to methylate. To methylate solution 70 g (0.360 mol) (L74) was added dropwise at the boiling point and the reaction mixture was heated for 45 min under reflux. The cooling mixture was poured onto a mixture of 500 mL ice and 300 mL water, acidified with 100 mL conc. HCl and the oily precipitating product was brought to crystallize under cooling with ice/sodium chloride bath. The crystals were sucked off, resumed in 100 mL methylene chloride and dried over sodium sulfate and evaporated. There were obtained 16.7 g of pale beige crystals. The aqueous phase was extracted three times with 100 mL of methylene chloride, the organic phase dried over sodium sulfate and evaporated. 30 g of crystalline product Methyl 4-oxotetrahydrothiophene-3-carboxylate was obtained. Yield: 46.7 g of light beige crystals (81 % of theory). mp 29-31 degC. TLC: Bz:MeOH:AcOH = 45:8:4, Rf = 0.75.
Methyl 4-oxotetrahydrothiophene-3-carboxylate synthesis

7400-45-5
2689-68-1
Synthesis of Methyl 4-oxotetrahydrothiophene-3-carboxylate from DIMETHYL 3-THIAADIPATE
Global( 116)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Changzhou Ansciep Chemical Co., Ltd.
+86 519 86305871 sales@ansciepchem.com CHINA 4242 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47464 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29827 58
Shaanxi Dideu Medichem Co. Ltd
+86-29-87569265 +86-18612256290 1056@dideu.com China 3965 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21149 58
Neostar United (Changzhou) Industrial Co., Ltd.
+86-519-519-85557386 marketing1@neostarunited.com China 8350 58
Xi'an Yutbon Pharmaceutical Technology Co., Ltd
029-81140587 +8618717328141 sales@yutbon.com China 437 58

View Lastest Price from Methyl 4-oxotetrahydrothiophene-3-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Methyl 4-oxotetrahydrothiophene-3-carboxylate pictures 2022-09-23 Methyl 4-oxotetrahydrothiophene-3-carboxylate
2689-68-1
US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE  pictures 2022-04-12 METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE
2689-68-1
US $1.10 / g 1g 99.00% 100 Tons Dideu Industries Group Limited
Methyl 4-oxotetrahydrothiophene-3-carboxylate pictures 2021-07-20 Methyl 4-oxotetrahydrothiophene-3-carboxylate
2689-68-1
US $1.00-1.00 / KG 1g 99% 50tons Shaanxi Dideu Medichem Co. Ltd
4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENONE AKOS 92615 tetrahydro-4-oxo-3-thiophenecarboxylicacimethylester METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE methyl tetrahydro-4-oxo-3-thenoate 4-Oxo-Tetrahydro-Thiophene-3-CarboxylicAcidMethylEster 4-CARBOMETHOXYTETRAHYDRO-3-THIOPHENE Methyl 4-oxotetrahydrothiophene-3-carboxylate, 95+% METHYL 3-OXOTETRAHYDROTHIOPHENE4-CARBOXYLATE Tetrahydro-4-oxo-3-thiophenecarboxylic acid methyl ester Methyl 4-oxotetrahydrothiophene-3-carboxylate ,97% Methyl 4-oxotetrahydrothiophene-3-carboxylate , Tech. 3-(Methoxycarbonyl)-4-oxotetrahydrothiophene, 3-(Methoxycarbonyl)-4-oxothiolane Methyl 4-oxotetrahydrothiophene-3-carboxylate, technical METHYL 4-OXOTETRAHYDROTHIOPHENE-3-CARBOXYLATE ISO 9001:2015 REACH 4-Oxytetrahydrophenol-3-carboxylic acid methyl ester 3-Carbomethoxytetrahydrothiophene-4-one 2689-68-1 KETONE Esters Thiophenes & Benzothiophenes Thiophenes & Benzothiophenes