ChemicalBook >> CAS DataBase List >>(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL structure

CAS No.: 173831-50-0

Chemical Name:: (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

Synonyms: SF120007;-2,2'-Bis(methoxymethoxy);(R)-(+)-2,2'-Bis(methoxymethox;(R)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAP&;2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL;2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHALENE;R-2,2'-Bis(methoxymethoxyl)-1,1'-binaphthyl;(S)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL;(R)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL;1,1'-Binaphthalene, 2,2'-bis(MethoxyMethoxy)-

CBNumber:: CB3368103

Molecular Formula:: C24H22O4

Molecular Weight:: 374.43

MDL Number:: MFCD03788935

MOL File:: 173831-50-0.mol

Last updated:2025-07-24 18:13:43

Product description	Number	Pack Size	Price
(R)-(+)-2,2′-Bis(methoxymethoxy)-1,1′-binaphthalene 97%	631582	250mg	$72.3
(R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl >98.0%(GC)	B3202	1g	$137
(R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl >98.0%(GC)	B3202	5g	$471
(R)-(+)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl, 98%	08-0170	250mg	$66
(R)-(+)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl, 98%	08-0170	1g	$193
More product size

Request For Quotation

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL Properties

Melting point	92-96 °C(lit.)
alpha	+85° (c 0.22, CHCl3)
Boiling point	477.8±45.0 °C(Predicted)
Density	1.182±0.06 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
solubility	soluble in Toluene
form	Powder
color	white
optical activity	[α]20/D +92°, c = 1% in chloroform
UNSPSC Code	12352005
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05,GHS09

Signal word

Danger

Hazard statements

H318-H410

Precautionary statements

P273-P280-P305+P351+P338-P391-P501

Hazard Codes

Xi,N

Risk Statements

41-50/53

Safety Statements

26-39-60-61-36/39-25

RIDADR

UN 3077 9/PG 3

WGK Germany

HS Code

29093090

NFPA 704

	1
0		0

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	631582	(R)-(+)-2,2′-Bis(methoxymethoxy)-1,1′-binaphthalene 97%	173831-50-0	250mg	$72.3	2023-06-20	Buy
TCI Chemical	B3202	(R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl >98.0%(GC)	173831-50-0	1g	$137	2025-07-31	Buy
TCI Chemical	B3202	(R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl >98.0%(GC)	173831-50-0	5g	$471	2025-07-31	Buy
Strem Chemicals	08-0170	(R)-(+)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl, 98%	173831-50-0	250mg	$66	2024-03-01	Buy
Strem Chemicals	08-0170	(R)-(+)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl, 98%	173831-50-0	1g	$193	2024-03-01	Buy

Product number	Packaging	Price	Buy
631582	250mg	$72.3	Buy
B3202	1g	$137	Buy
B3202	5g	$471	Buy
08-0170	250mg	$66	Buy
08-0170	1g	$193	Buy

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL Chemical Properties,Uses,Production

Reaction

Starting material for the preparation of a variety of 3,3'-substituted binaphthols.

Chemical Properties

Colorless solid

Uses

3- or 3,3′-di-substituted products can be obtained easily via ortho-metallation and subsequent treatment with an electrophile to give the corresponding BINOL derivatives.

Uses

An intermediate in the symmetric synthesis of BINOL-terpyridine ligands.

Synthesis

107-30-2

602-09-5

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

173831-50-0

Sodium hydride (NaH, 1.92 g, 80 mmol) was slowly added to N,N-dimethylformamide (DMF, 30 mL) under ice bath conditions. Subsequently, a tetrahydrofuran (THF, 50 mL) solution of 1,1'-bi-2-naphthol (BINOL, 10 g, 34 mmol) was added slowly dropwise to the above mixture for 20 min. after 30 min, chloromethyl methyl ether (6.4 g, 80 mmol) was added slowly dropwise for the same period of time. The reaction process was monitored by thin layer chromatography (TLC). The reaction mixture was extracted with chloroform and water after stirring for 1 h. The organic layer was separated to obtain the crude product. The crude product was further purified by silica gel column chromatography with petroleum ether/ethyl acetate (5:1, v/v) as eluent. Finally, (R)-2,2'-bis(methoxymethoxy)-1,1'-binaphthyl was obtained in 90% yield. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 7.95-7.93 (d, J = 9.6 Hz, 2H), 7.87-7.85 (d, J = 8.4 Hz, 2H), 7.58-7.56 (d, J = 9.6 Hz, 2H), 7.35-7.31 (m, 2H), 7.23-7.14 (m, 4H ), 5.08-4.96 (q, J = 6.8 Hz, 4H), 3.13 (s, 6H).

References

[1] Organic Letters, 2004, vol. 6, # 16, p. 2701 - 2704
[2] Tetrahedron Asymmetry, 2002, vol. 13, # 19, p. 2161 - 2166
[3] Chemistry - A European Journal, 2018, vol. 24, # 48, p. 12607 - 12612
[4] Chemistry Letters, 1995, # 12, p. 1113 - 1114
[5] Organic Preparations and Procedures International, 1995, vol. 27, # 6, p. 685 - 690

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL synthesis

Synthesis of (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL from 2-Naphthol

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL Preparation Products And Raw materials

Raw materials

Hypochlorous acid, methoxymethyl ester (9CI) (S)-(-)-1,1'-Bi-2-naphthol 2-Naphthol 1,1'-Bi-2-naphthol Chloromethyl methyl ether

N,N-Dimethylformamide Sodium hydride Tetrahydrofuran

1of2

Preparation Products

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL Suppliers

Global( 91)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13505	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29850	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	20342	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9644	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418684 +8618949823763	sales@tnjchem.com	China	25356	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Shanghai Acmec Biochemical Technology Co., Ltd.	+86-18621343501; +undefined18621343501	product@acmec-e.com	China	33338	58
Aladdin Scientific		tp@aladdinsci.com	United States	57505	58

Supplier	Advantage
Shanghai Daken Advanced Materials Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Alchem Pharmtech,Inc.	58
CD Chemical Group Limited	58
changzhou huayang technology co., ltd	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58

View Lastest Price from (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-09-02	(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL 173831-50-0	US $1.00 / KG	1KG	98%	1lg; 2kg; 5kg; 10kg; 100kg	Career Henan Chemical Co

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL
173831-50-0
US $1.00 / KG
98%
Career Henan Chemical Co

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL Spectrum

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL(173831-50-0)¹HNMR

173831-50-0((R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL)Related Search:

(R)-(+)-2,2'-Dimethoxy-1,1'-binaphthalene p-Anisaldehyde 1,1'-BINAPHTHYL (R)-(+)-6,6'-DIBROMO-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL (R)-(+)-6,6'-DIBROMO-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

(R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL (R)-(+)-6,6'-DIBROMO-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL 2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL-3,3'-DIYLDIBORONIC ACID (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL

1of2

(R)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAP& (R)-(+)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl,98% 2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHALENE 2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHALENE (R)-(+)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL (R)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL (S)-(-)-2,2'-BIS(METHOXYMETHOXY)-1,1-BINAPHTHALENE (S)-(-)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL (S)-2,2'-BIS(METHOXYMETHOXY)-1,1'-BINAPHTHYL (R)-(+)-2,2'-Bis(methoxymethox (1R)-2,2'-Bis(MethoxyMethoxy)-1,1'-binaphthalene -2,2'-Bis(methoxymethoxy) (R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl, 99%e.e. 1,1'-Binaphthalene, 2,2'-bis(MethoxyMethoxy)- R-2,2'-Bis(methoxymethoxyl)-1,1'-binaphthyl SF120007 (R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl> 1,1'-Binaphthalene, 2,2'-bis(methoxymethoxy)-, (1R)- (R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthalene (R)-(+)-2,2′-Bis(methoxymethoxy)-1,1′-binaphthalene (R)-(+)-2,2′-Bis(methoxymethoxy)-1,1′-binaphthalene, CAS 173831-50-0 173831-50-0 CH3OCH2OC10H62 Privileged Ligands Asymmetric Synthesis BINOLs Chiral Catalysts, Ligands, and Reagents BINOL Series Chiral Oxygen BINOLs Chiral Catalysts, Ligands, and Reagents Privileged Ligands and Complexes Aromatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals Other Ligands Catalysis and Inorganic Chemistry Chemical Synthesis