3-Amino-3-iminopropanoic acid ethyl ester hydrochloride
- CAS No.
- 57508-48-2
- Chemical Name:
- 3-Amino-3-iminopropanoic acid ethyl ester hydrochloride
- Synonyms
- ETHYL AMIDINOACETATE HCL;2-Amidinoacetate HydrochL;Ethyl amidinoacetate hydrochloride;carbethoxyacetamidine hydrochloride;Ethyl 2-Amidinoacetate Hydrochloride;ethyl 2-carbaMiMidoylacetate hydrochloride;Ethyl 3-aMino-3-iMinopropanate hydrochloride;Ethyl3-amino-3-iminopropanoate hydrochloride;3-AMINO-3-IMINO-PROPANOIC ACID, ETHYL ESTER HCL;1-amino-3-ethoxy-3-oxopropan-1-iminium chloride
- CBNumber:
- CB3368769
- Molecular Formula:
- C5H11ClN2O2
- Molecular Weight:
- 166.61
- MDL Number:
- MFCD06797615
- MOL File:
- 57508-48-2.mol
| Product description | Number | Pack Size | Price |
| 3-Amino-3-imino-propanoicacid,ethylesterhydrochloride | A609918 | 100mg | $45 |
| 3-Amino-3-imino-propanoicacid,ethylesterhydrochloride | A609918 | 250mg | $55 |
| 3-Amino-3-imino-propanoicacid,ethylesterhydrochloride | A609918 | 500mg | $65 |
| 3-Amino-3-imino-propanoic acid ethyl ester HCl | FA53319 | 1g | $80 |
| Carbamimidoyl-acetic acid ethyl ester hydrochloride | 020077 | 5g | $57 |
| More product size | |||
| Melting point | 105-108℃ |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| form | Solid |
| Appearance | White to light yellow Solid |
| InChI | InChI=1S/C5H10N2O2.ClH/c1-2-9-5(8)3-4(6)7;/h2-3H2,1H3,(H3,6,7);1H |
| InChIKey | VOHFLYOSVGWQOS-UHFFFAOYSA-N |
| SMILES | C(C(OCC)=O)C(N)=N.Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| NFPA 704 |
|
3-Amino-3-iminopropanoic acid ethyl ester hydrochloride price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A609918 | 3-Amino-3-imino-propanoicacid,ethylesterhydrochloride | 57508-48-2 | 100mg | $45 | 2021-12-16 | Buy |
| TRC | A609918 | 3-Amino-3-imino-propanoicacid,ethylesterhydrochloride | 57508-48-2 | 250mg | $55 | 2021-12-16 | Buy |
| TRC | A609918 | 3-Amino-3-imino-propanoicacid,ethylesterhydrochloride | 57508-48-2 | 500mg | $65 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA53319 | 3-Amino-3-imino-propanoic acid ethyl ester HCl | 57508-48-2 | 1g | $80 | 2021-12-16 | Buy |
| Matrix Scientific | 020077 | Carbamimidoyl-acetic acid ethyl ester hydrochloride | 57508-48-2 | 5g | $57 | 2021-12-16 | Buy |
3-Amino-3-iminopropanoic acid ethyl ester hydrochloride Chemical Properties,Uses,Production
Uses
It is used as a pharmaceutical intermediate.
Synthesis
27317-59-5
57508-48-2
The general procedure for the synthesis of ethyl 3-amidinopropionate hydrochloride from ethyl 3-ethoxy-3-iminopropionate was as follows: ethyl 3-amino-3-ethoxyacrylate (760 mg, 4.78 mmol) and ammonium chloride (270 mg, 5.0 mmol) were dissolved in ethanol (4.0 mL) in a glass tube rated for 10 mL pressure. The reaction was carried out using a CEM Discover microwave synthesizer at an initial magnetron power of 200 W for 1 h at 120°C (hold time). Upon completion of the reaction, the reaction mixture was cooled in a stream of compressed air and subsequently filtered. The filtrate was concentrated by vacuum evaporation and the residue was ground with diethyl ether to afford ethyl 3-amidinopropionate hydrochloride (923 mg, 78% yield) as a colorless solid, which was ready for use without further purification. The product characterization data were as follows: νmax (neat)/ cm-1 3300, 3095, 1738, 1687; δH (500 MHz; d6-DMSO)/ ppm 9.16 (2H, broad single peak, NH2), 8.88 (2H, broad single peak, NH2), 4.15 (2H, quartet peak, J = 7.1 Hz, OCH2), 3.63 (2H, single peak, CH2), 1.22 (3H, triple peak, J = 7.1 Hz, CH3); δC (125 MHz, d6-DMSO)/ ppm 166.7 (C=O), 163.6 (C=N), 61.9 (OCH2), 38.2 (CH2), 14.4 (CH3); m/z (EI) 130 (M-+).
References
[1] Synlett, 2016, vol. 27, # 11, p. 1728 - 1732
[2] Chemical and Pharmaceutical Bulletin, 1995, vol. 43, # 5, p. 788 - 796
[3] Patent: WO2008/33745, 2008, A2. Location in patent: Page/Page column 70
[4] Patent: WO2008/33747, 2008, A2. Location in patent: Page/Page column 254-255
[5] European Journal of Medicinal Chemistry, 2011, vol. 46, # 12, p. 6002 - 6014
3-Amino-3-iminopropanoic acid ethyl ester hydrochloride Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29798 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 +86-17392581500 | 1015@dideu.com | China | 3965 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8647 | 58 |
View Lastest Price from 3-Amino-3-iminopropanoic acid ethyl ester hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-07-25 | 3-Amino-3-iminopropanoic acid ethyl ester hydrochloride
57508-48-2
|
US $0.00 / kg | 1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | |
 |
2020-01-09 | 3-Amino-3-iminopropanoic acid ethyl ester hydrochloride
57508-48-2
|
US $1.00 / ASSAYS | 1ASSAYS | 85.0-99.8% | 20tons | Career Henan Chemical Co |
-
- 3-Amino-3-iminopropanoic acid ethyl ester hydrochloride
57508-48-2
- US $0.00 / kg
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- 3-Amino-3-iminopropanoic acid ethyl ester hydrochloride
57508-48-2
- US $1.00 / ASSAYS
- 85.0-99.8%
- Career Henan Chemical Co
