FELBAMATE-D4
- CAS No.
- 106817-52-1
- Chemical Name:
- FELBAMATE-D4
- Synonyms
- W-554-d4;Taloxa-d4;Felbatol-d4;Felbamyl-d4;FELBAMATE-D4;ADD-03055-d4;WKGXYQFOCVYPAC-KXGHAPEVSA-N;2-Phenyl-1,3-propanedioldicarbamate-d4;Carbamic Acid 2-Phenyltrimethylene-d4 Ester;2-Phenyl-(1,1,3,3-tetra-deuterio)-1,3-propanediol Dicarbamate
- CBNumber:
- CB3370089
- Molecular Formula:
- C11H10D4N2O4
- Molecular Weight:
- 242.26
- MDL Number:
- MFCD08063587
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H336-H372 |
| Precautionary statements | P260-P264-P270-P271-P304+P340-P312-P314-P403+P233-P405-P501 |
FELBAMATE-D4 price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 28489 | Felbamate-d4 | 106817-52-1 | 1mg | $84 | 2024-03-01 | Buy |
| Cayman Chemical | 28489 | Felbamate-d4 | 106817-52-1 | 5mg | $341 | 2024-03-01 | Buy |
| Cayman Chemical | 28489 | Felbamate-d4 | 106817-52-1 | 500μg | $44 | 2024-03-01 | Buy |
| TRC | F231002 | Felbamate-d4 | 106817-52-1 | 5mg | $185 | 2021-12-16 | Buy |
| Usbiological | 011939 | Felbamate-d4 | 106817-52-1 | 2.5mg | $460 | 2021-12-16 | Buy |
FELBAMATE-D4 Chemical Properties,Uses,Production
Description
Felbamate-d4 is intended for use as an internal standard for the quantification of felbamate by GC- or LC-MS. Felbamate is an inhibitor of NMDA receptors and a modulator of GABAA receptors that also has broad-spectrum inhibitory activity against excitatory amino acid receptors. It binds to NMDA channels with dissociation constants of approximately 200, 110, and 55 μM in the resting, activated, and desensitized states, respectively, and inhibits NMDA currents in a use-dependent manner. Felbamate is a positive modulator of α1β2γ2S, α1β3γ2S, α2β2γ2S, and α2β3γ2S subunit-containing GABAA receptors expressed in X. laevis oocytes, with negative modulation of GABAA receptors containing the subunits α1β1, α1β3γ2L, α4β1γ2S, α4β3γ2S, and α6β1γ2S. It inhibits seizures induced by maximal electroshock, pentylenetetrazole , and picrotoxin in mice (ED50s = 16.3, 5.51, and 5.23 mg/kg, respectively). Formulations containing felbamate have been used in the treatment of severe refractory seizures.
Chemical Properties
White Solid
Uses
Antiepileptic, structurally similar to meprobamate.
FELBAMATE-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Guangzhou PI PI Biotech Inc | +86-020-81716320 +86-13602409664 | Sales@pipitech.com | China | 3635 | 55 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9685 | 58 |
| Cato Research Chemicals Inc. | 020-81960175 | min.he@cato-chem.com | China | 1958 | 55 |
| Shanghai Champ Biopharmaceuticals Co., Ltd. | 021-61537865 13585780846 | sales@champchem.com | China | 349 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Manhag Testing Technology Co., Ltd | 020-020-3846236 17688849268 | 2443244976@qq.com | China | 7775 | 58 |
| TCI (Shanghai) Chemical Trading Co., Ltd. | 021-61109150 | sales@tcisct.com | China | 31183 | 58 |