ChemicalBook >> CAS DataBase List >>3-Carboxyphenylboronic acid
3-Carboxyphenylboronic acid
- CAS No.
- 25487-66-5
- Chemical Name:
- 3-Carboxyphenylboronic acid
- Synonyms
- 3-BORONOBENZOIC ACID;m-carboxybenzeneboronicacid;AKOS BRN-0007;"25487-66-5 ";3-CarboxyphenyL;3-borono-benzoicaci;RARECHEM AH PB 0148;m-borono-benzoicaci;3-Carboxyphenylboron;Benzoic acid, 3-borono-
- CBNumber:
- CB3376096
- Molecular Formula:
- C7H7BO4
- Molecular Weight:
- 165.94
- MDL Number:
- MFCD00036833
- MOL File:
- 25487-66-5.mol
- MSDS File:
- SDS
Last updated:2026-01-13 11:18:51
| Product description | Number | Pack Size | Price |
| 3-Carboxyphenylboronic acid ≥95% | 456764 | 1g | $52.12 |
| 3-Carboxyphenylboronic acid ≥95% | 456764 | 10g | $67.35 |
| 3-Carboxyphenylboronic Acid (contains varying amounts of Anhydride) | C2028 | 1g | $38 |
| 3-Carboxyphenylboronic Acid (contains varying amounts of Anhydride) | C2028 | 5g | $109 |
| 3-Carboxyphenylboronic acid, min. 97% | 05-0399 | 1g | $62 |
| More product size | |||
| Melting point | 243-247 °C (lit.) |
|---|---|
| Boiling point | 434.5±47.0 °C(Predicted) |
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly), Water (Slightly) |
| pka | 4.21±0.10(Predicted) |
| form | Crystalline Powder |
| color | Off-white |
| Water Solubility | 2.5 g/100 mL |
| BRN | 2967400 |
| InChI | InChI=1S/C7H7BO4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4,11-12H,(H,9,10) |
| InChIKey | DBVFWZMQJQMJCB-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC=CC(B(O)O)=C1 |
| CAS DataBase Reference | 25487-66-5(CAS DataBase Reference) |
| UNSPSC Code | 12352103 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H303-H335-H315-H319 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 37/39-26-36 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | CY8750000 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29163990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Toxicity | mouse,LD50,intravenous,2560mg/kg (2560mg/kg),"Boron, Metallo-Boron Compounds and Boranes," Adams, R.M., ed., New York, John Wiley & Sons, Inc., 1964Vol. -, Pg. 693, 1964. | |||||||||
| NFPA 704 |
|
3-Carboxyphenylboronic acid price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 456764 | 3-Carboxyphenylboronic acid ≥95% | 25487-66-5 | 1g | $52.12 | 2025-07-31 | Buy |
| Sigma-Aldrich | 456764 | 3-Carboxyphenylboronic acid ≥95% | 25487-66-5 | 10g | $67.35 | 2025-07-31 | Buy |
| TCI Chemical | C2028 | 3-Carboxyphenylboronic Acid (contains varying amounts of Anhydride) | 25487-66-5 | 1g | $38 | 2025-07-31 | Buy |
| TCI Chemical | C2028 | 3-Carboxyphenylboronic Acid (contains varying amounts of Anhydride) | 25487-66-5 | 5g | $109 | 2025-07-31 | Buy |
| Strem Chemicals | 05-0399 | 3-Carboxyphenylboronic acid, min. 97% | 25487-66-5 | 1g | $62 | 2024-03-01 | Buy |
3-Carboxyphenylboronic acid Chemical Properties,Uses,Production
Chemical Properties
3-Carboxyphenylboronic acid is off-white crystalline powder
Uses
suzuki reaction
Uses
3-Carboxyphenylboronic acid can be used as a substrate in the preparation of:
- Biaryl derivatives by reacting with bromoaniline through the Suzuki-Miyaura coupling reaction.
- Boronic acid-functionalized block copolymer.
- 1H-Imidazo[1,2-a]quinoxaline derivatives.
Uses
3-Carboxyphenylboronic acid is used in Suzuki coupling chemistry.1,2,3
Synthesis
150255-96-2
25487-66-5
1. Synthesis of 3-carboxyphenylboronic acid: 10 g (68 mmol) of 3-cyanophenylboronic acid was suspended in 40 mL of ethylene glycol with 15.26 g (272 mmol, 4 eq.) of potassium hydroxide powder, heated to 175 °C and maintained for 3 hours. After completion of the reaction, the reaction mixture was cooled and diluted with 60 mL of water. The pH was adjusted to 2-3 with 32% hydrochloric acid solution, colorless crystalline 3-carboxyphenylboronic acid was precipitated and the product was separated by filtration. The resulting crystals were washed with water and dried under mild vacuum at 35 °C. The final product was 10.04 g in mass. The final product was 10.04 g (60.5 mmol, 89% yield).
References
[1] Patent: US2009/286995, 2009, A1. Location in patent: Page/Page column 4
3-Carboxyphenylboronic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
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Global( 565)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Maison Chemical Co.,Ltd. | +8615511852758 | sales@maisonchem.com.cn | China | 484 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8754 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5242 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20129 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13619 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21600 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
View Lastest Price from 3-Carboxyphenylboronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-05 | 3-Carboxyphenylboronic acid
25487-66-5
|
US $1.00 / kg | 1kg | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2026-01-04 | 3-Carboxyphenylboronic acid
25487-66-5
|
US $0.00-0.00 / kg | 0.1kg | 99.0%min | 2000kg | Hangzhou ICH Biofarm Co., Ltd | |
 |
2025-12-29 | 3-Carboxyphenylboronic acid
25487-66-5
|
US $0.00 / kg | 1kg | 99% | according to customer's requirements | Changzhou waston chemical technology Co.,Ltd |
-
- 3-Carboxyphenylboronic acid
25487-66-5
- US $1.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3-Carboxyphenylboronic acid
25487-66-5
- US $0.00-0.00 / kg
- 99.0%min
- Hangzhou ICH Biofarm Co., Ltd
-
- 3-Carboxyphenylboronic acid
25487-66-5
- US $0.00 / kg
- 99%
- Changzhou waston chemical technology Co.,Ltd
25487-66-5(3-Carboxyphenylboronic acid)Related Search:
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3-AMINO-5-METHOXYCARBONYLPHENYLBORONIC ACID, HCL
1of4
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RARECHEM AH PB 0148
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3-CARBOXYBENZENEBORONIC ACID
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3-(DIHYDROXYBORYL)BENZOIC ACID
3-(DIHYDROXYBORANE)BENZOIC ACID
3-(DIHYDROXYBORONYL)BENZOIC ACID
3-Carboxyphenylboronicacid,min.97%
3-CARBOXYBENZENEBORONIC ACID 98%
3-Carboxyphenylboronic Acid (contains varying amounts of Anhydride)
3-Carboxyphenylboronic acid ,98%
3-Carboxyphenylboronic acid, min. 97%
(3-Formyloxyphenyl)boronicacid
3-Carboxyphenylboron
3-(dihydroxyboryl)benzoic acid(SALTDATA: FREE)
3-Carboxyphenylboronic acid, 98% 5GR
"25487-66-5 "
3-Carboxyphenylboronic acid Eltrombopag
Lumacaftor
3-CarboxyphenyL
Benzoic acid, 3-borono-
3-Carboxyphenylboronic acid 25487-66-5
3-Carboxybenzeneboronic Acid extrapure, 97%
m-carboxybenzeneboronicacid
3-BORONOBENZOIC ACID
Eltrombopag Impurity 31
Benzeneboronic acid, m-carboxy-
3-Carboxyphenylboronic acid, 97%
3-Carboxyphenylboronic acid - [C2160]
25487-66-5
25487-66-6
C7H7BO4
HO2CC6H4BOH2
HOOCC6H4BOH2
BORONIC ACID
B (Classes of Boron Compounds)
Boronic Acids
Boronic Acids and Derivatives
Aryl
Organometallic Reagents
Substituted Boronic Acids
B (Classes of Boron Compounds)
CHIRAL CHEMICALS
Boronic Acids & Esters
Phenyls & Phenyl-Het
Boronic Acids
Boronic Acids and Derivatives
organic or inorganic borate
Boronic Acids & Esters
Phenyls & Phenyl-Het
Boronic acids
Boronic Acid
