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Trazodone hydrochloride

Description References
Trazodone hydrochloride
Trazodone hydrochloride structure
CAS No.
25332-39-2
Chemical Name:
Trazodone hydrochloride
Synonyms
kb-831;af1161;tombran;Undepre;BiMaran;Mesyrel;)-onehcl;thombran;Trittico;molipaxin
CBNumber:
CB3376874
Molecular Formula:
C19H23Cl2N5O
Formula Weight:
408.32
MOL File:
25332-39-2.mol

Trazodone hydrochloride Properties

Melting point:
223-226?C
Flash point:
9℃
storage temp. 
-20°C Freezer
solubility 
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 23.3 mg/mL
form 
powder
color 
off-white
PH
pH (10g/l, 25℃) : 3.9~4.5
Water Solubility 
Soluble at 25mg/ml in methanol. Also soluble in 0.1M HCl or DMSO. Insoluble in water /n
InChIKey
OHHDIOKRWWOXMT-UHFFFAOYSA-N
CAS DataBase Reference
25332-39-2(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,Xi,T,F
Risk Statements  22-40-36/37/38-39/23/24/25-23/24/25-11
Safety Statements  22-36-37/39-26-45-36/37-16-7
RIDADR  3249
WGK Germany  3
RTECS  XZ5660000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29335990
Hazardous Substances Data 25332-39-2(Hazardous Substances Data)
Toxicity LD50 i.v. in mice: 96 mg/kg (Silvestrini, Quadri)
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P201 Obtain special instructions before use.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P311 Call a POISON CENTER or doctor/physician.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P405 Store locked up.

Trazodone hydrochloride price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T-030 Trazodone hydrochloride solution 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material 25332-39-2 030-1ml $26.3 2018-11-13 Buy
Sigma-Aldrich 1673500 Trazodone hydrochloride United States Pharmacopeia (USP) Reference Standard 25332-39-2 200mg $352.8 2018-11-13 Buy
Alfa Aesar J63070 Trazodone hydrochloride 98+% 25332-39-2 5g $224 2018-11-20 Buy
Alfa Aesar J63070 Trazodone hydrochloride 98+% 25332-39-2 1g $53.5 2018-11-20 Buy
Cayman Chemical 19048 Trazodone (hydrochloride) ≥98% 25332-39-2 1mg $20 2018-11-19 Buy

Trazodone hydrochloride Chemical Properties,Uses,Production

Description

Trazodone Hydrochloride belongs to the hydrochloride salt form of trazodone with antidepressant and sedative activities, which is primarily used in the treatment of major depression. It serves as a serotonin uptake inhibitor that is effective for patients suffering from major depressive disorders and other subsets of depressive disorders, which is especially helpful for geriatric patients with severe agitation and certain depressive disorders associated with insomnia and anxiety since it has proved that trazodone also has anti-anxiety (anxiolytic) and sleep-inducing (hypnotic) effects. Besides, it is often prescribed as a sedative that is used for the treatment of panic attacks, aggressive behavior, agoraphobia, and cocaine withdrawal in combination with other drugs. Trazodone Hydrochloride is an oral drug that functions by affecting the balance of chemicals (neurotransmitters) within the brain that nerves use to communicate with (stimulate) each other.

References

https://en.wikipedia.org/wiki/Trazodone
http://www.medicinenet.com/trazodone/article.htm
https://www.drugbank.ca/drugs/DB00656
http://bodyandhealth.canada.com/drug/getdrug/ratio-trazodone
https://pubchem.ncbi.nlm.nih.gov/compound/62935#section=Top

Chemical Properties

White to Off-White Solid

Uses

antihistamine

Uses

Monoamine reuptake inhibitor; antidepressant.

Definition

ChEBI: A hydrochloride salt prepared from equimolar amounts of trazodone and hydrogen chloride.

Trazodone hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products


Trazodone hydrochloride Suppliers

Global( 183)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19954 60
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 894 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58
Hubei Jusheng Technology Co.,Ltd.
86-188-71490254
peter@hubeijusheng.com CHINA 20229 58
Haihang Industry Co.,Ltd
86-531-88032799
+86 531 8582 1093 export@haihangchem.com CHINA 4525 58
Jinan Tenglong Chemical Co.,Ltd
Whatsapp:+8615563263311 Skype:live:smions7080
smions7080@gmail.com CHINA 770 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19997 58

View Lastest Price from Trazodone hydrochloride manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-01 Trazodone hydrochloride
25332-39-2
US $100.00 / KG 1KG 99% Customized career henan chemical co

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