4-Formyl-2-methylthiazole
- CAS No.
- 20949-84-2
- Chemical Name:
- 4-Formyl-2-methylthiazole
- Synonyms
- IFLAB-BB F2124-0689;4-FORMYL-2-METHYLTHIAZOLE;2-Methyl-4-forMylthiazole;4-Formyl-2-methyl-1,3-thiazole;2-Methyl-4-thiazolecarbaldehyde;2-Methylthiazole-4-carboxaldehyde;2-Methyl-4-thiazolecarboxaldehyde;4-THIAZOLECARBOXALDEHYDE, 2-METHYL-;2-METHYL-1,3-THIAZOLE-4-CARBALDEHYDE;2-Methyl-1,3-thiazole-4-carboxaldehyde
- CBNumber:
- CB3378469
- Molecular Formula:
- C5H5NOS
- Molecular Weight:
- 127.16
- MDL Number:
- MFCD06655197
- MOL File:
- 20949-84-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Methylthiazole-4-carboxaldehyde 97% | 717231 | 500mg | $124 |
| 4-Formyl-2-methylthiazole | F701245 | 250mg | $70 |
| 2-Methyl-1,3-thiazole-4-carboxaldehyde 97% | OR5201 | 250mg | $25 |
| 4-Formyl-2-methylthiazole 96% | 069422 | 5g | $438 |
| 4-Formyl-2-methylthiazole 96% | 069422 | 1g | $145 |
| More product size | |||
| Melting point | 56-58 |
|---|---|
| Boiling point | 219.0±13.0 °C(Predicted) |
| Density | 1.270±0.06 g/cm3(Predicted) |
| Flash point | 110℃ |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 1.22±0.10(Predicted) |
| Appearance | Off-white to yellow Solid |
| InChI | InChI=1S/C5H5NOS/c1-4-6-5(2-7)3-8-4/h2-3H,1H3 |
| InChIKey | AEHWVNPVEUVPMT-UHFFFAOYSA-N |
| SMILES | S1C=C(C=O)N=C1C |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Harmful | |||||||||
| HS Code | 2934100090 | |||||||||
| NFPA 704 |
|
4-Formyl-2-methylthiazole price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 717231 | 2-Methylthiazole-4-carboxaldehyde 97% | 20949-84-2 | 500mg | $124 | 2023-06-20 | Buy |
| TRC | F701245 | 4-Formyl-2-methylthiazole | 20949-84-2 | 250mg | $70 | 2021-12-16 | Buy |
| Apolloscientific | OR5201 | 2-Methyl-1,3-thiazole-4-carboxaldehyde 97% | 20949-84-2 | 250mg | $25 | 2021-12-16 | Buy |
| Matrix Scientific | 069422 | 4-Formyl-2-methylthiazole 96% | 20949-84-2 | 5g | $438 | 2021-12-16 | Buy |
| Matrix Scientific | 069422 | 4-Formyl-2-methylthiazole 96% | 20949-84-2 | 1g | $145 | 2021-12-16 | Buy |
4-Formyl-2-methylthiazole Chemical Properties,Uses,Production
Chemical Properties
Yellow Powder
Synthesis
6436-59-5
20949-84-2
The general procedure for the synthesis of 2-methyl-4-thiazolecarboxaldehyde using ethyl 2-methylthiazole-4-carboxylate as starting material was as follows: to a solution of ethyl 2-methylthiazole-4-carboxylate (1.00 g, 5.8 mmol) in toluene (18 mL) was slowly added dropwise to a solution of diisobutylaluminum hydroxide in dichloromethane (11.1 mL, 1 M) at -78 °C. After the dropwise addition was completed, the reaction system was kept at -78 °C and stirring was continued for 4 hours. Subsequently, the reaction was quenched by the addition of acetic acid (0.46 mL) and concentrated by slowly warming the reaction mixture to 25 °C. The concentrated residue was treated with dichloromethane and Rochelle's salt with vigorous stirring until a clarified two-phase solution was formed (about 10 min). The organic and aqueous layers were separated, and the organic layer was washed sequentially with 10% NaHCO3 solution and saturated saline, then dried with anhydrous Na2SO4, filtered and concentrated. Finally, the residue was purified by silica gel column chromatography, using 14% ethyl acetate in hexane solution as eluent, to obtain the target product 2-methyl-4-thiazolecarboxaldehyde (0.28 g, 38% yield).
References
[1] Organic Letters, 2008, vol. 10, # 8, p. 1565 - 1568
[2] Angewandte Chemie - International Edition in English, 1997, vol. 36, # 1-2, p. 166 - 168
[3] Journal of the American Chemical Society, 1997, vol. 119, # 34, p. 7974 - 7991
[4] Organic Letters, 2012, vol. 14, # 24, p. 6354 - 6357
[5] Angewandte Chemie - International Edition, 2000, vol. 39, # 1, p. 209 - 213
4-Formyl-2-methylthiazole Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Accendatech Co., Ltd. | +8613132578992 | yunhao.liu@accendatech.com | China | 251 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | info@edengenechem.com | China | 2176 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
View Lastest Price from 4-Formyl-2-methylthiazole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-12 | 4-FORMYL-2-METHYLTHIAZOLE
20949-84-2
|
US $1.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 4-FORMYL-2-METHYLTHIAZOLE
20949-84-2
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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