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Ethyl isocyanate

Ethyl isocyanate
Ethyl isocyanate structure
Chemical Name:
Ethyl isocyanate
C2H5NCO;ethyl爄socyanate;ETHYL ISOCYANATE;isocyanatoethene;isocyanato-ethan;Isocyanatoethane;isocyanato-Ethane;1-Isocyanatoethane;ethane,isocyanato-;isocyanated’ethyle
Molecular Formula:
Formula Weight:
MOL File:

Ethyl isocyanate Properties

Melting point:
Boiling point:
60 °C(lit.)
0.898 g/mL at 25 °C(lit.)
vapor pressure 
4.34 psi ( 20 °C)
refractive index 
n20/D 1.381(lit.)
Flash point:
20 °F
storage temp. 
Water Solubility 
Moisture Sensitive
CAS DataBase Reference
109-90-0(CAS DataBase Reference)
NIST Chemistry Reference
Ethane, isocyanato-(109-90-0)
EPA Substance Registry System
Ethyl isocyanate (109-90-0)
  • Risk and Safety Statements
Signal word  Danger
Hazard statements  H330-H225-H301-H312+H332-H315-H319-H334-H335
Precautionary statements  P301+P310a-P303+P361+P353-P304+P340-P320-P330-P405-P501a-P210-P261-P280-P301+P310-P305+P351+P338-P342+P311
Hazard Codes  F,T
Risk Statements  11-20/21-25-36/37/38-42
Safety Statements  16-26-36/37/39-45
RIDADR  UN 2481 3/PG 1
WGK Germany  3
RTECS  NQ8825000
HazardClass  3.1
PackingGroup  I
HS Code  29291090

Ethyl isocyanate price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E33300 Ethyl isocyanate 98% 109-90-0 5g $46.8 2021-03-22 Buy
Sigma-Aldrich E33300 Ethyl isocyanate 98% 109-90-0 25g $102 2021-03-22 Buy
Sigma-Aldrich E33300 Ethyl isocyanate 98% 109-90-0 500g $1660 2021-03-22 Buy

Ethyl isocyanate Chemical Properties,Uses,Production


Ethyl isocyanate is part of a group of isocyanates that react with primary and secondary amines to form urea derivatives and carbamates. Ethyl isocyanate (among other isocyanate compounds, such as toluene isocyanate) are also thought to be the most common cause of occupational asthma.

Chemical Properties

Ethyl Isocyanate is a clear, colorless liquid with a pungent odor.


Pharmaceutical and pesticide intermediate.


ChEBI: An isocyanate having an ethyl group attached to the nitrogen.

General Description

A colorless liquid. Less dense than water and insoluble in water. Flash point below 30°F. May irritate skin, eyes, and mucous membranes. May be lethal by Inhalation . Used to make pharmaceuticals and pesticides.

Air & Water Reactions

Highly flammable. Insoluble in water. Ethyl isocyanate may react with water to produce a corrosive liquid and carbon dioxide gas.

Reactivity Profile

When heated to decomposition Ethyl isocyanate emits toxic fumes of nitrogen oxides [Sax, 9th ed., 1996, p. 1572].


Strong irritant to tissue.

Health Hazard

TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Bromoacetates and chloroacetates are extremely irritating/lachrymators. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.

Safety Profile

Poison by intravenous route. Mutation data reported. A flammable liquid. When heated to decomposition it emits toxic fumes of NOx. See also CYANATES.

Potential Exposure

Ethyl isocyanate is used to make pharmaceuticals and pesticides


UN2481 Ethyl isocyanate, Hazard class: 6.1; Labels: 6.1-Poison Inhalation Hazard, 3-Flammable liquid, Inhalation Hazard Zone A. Cylinders must be transported in a secure upright position, in a well-ventilated truck. Protect cylinder and labels from physical damage. The owner of the compressed gas cylinder is the only entity allowed by federal law (49CFR) to transport and refill them. It is a violation of transportation regulations to refill compressed gas cylinders without the express written permission of the owner.

Purification Methods

Fractionate the isocyanate through an efficient column preferably in an inert atmosphere and store it in aliquots in sealed tubes [Bieber J Am Chem Soc 74 4700 1952, Slocombe et al. J Am Chem Soc 72 1888 1950]. [Beilstein 4 IV 402.]


Vapor may form explosive mixture with air. May form explosive mixture with air. Isocyanates are highly flammable and reactive with many compounds, even with themselves. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Reaction with moist air, water or alcohols may form amines and insoluble polyureas and react exothermically, releasing toxic, corrosive or flammable gases, including carbon dioxide; and, at the same time, may generate a violent release of heat increasing the concentration of fumes in the air. Incompatible with amines, aldehydes, alkali metals, ammonia, carboxylic acids, caprolactum, alkaline materials, glycols, ketones, mercaptans, hydrides, organotin catalysts, phenols, strong acids, strong bases, strong reducing agents such as hydrides, urethanes, and ureas. Elevated temperatures or contact with acids, bases, tertiary amines, and acyl-chlorides may cause explosive polymerization. Contact Attacks some plastics, rubber and coatings. Contact with metals may evolve flammable hydrogen gas. May accumulate static electrical charges, and may cause ignition of its vapors.

Ethyl isocyanate Preparation Products And Raw materials

Raw materials

Preparation Products

Ethyl isocyanate Suppliers

Global( 147)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shanghai Rlavie Technology Co ltd
17717059219 021-67759270
021-67759270 CHINA 799 58
Capot Chemical Co.,Ltd.
+86(0)13336195806 +86-571-85586718
+86-571-85864795 China 20010 60
Henan DaKen Chemical CO.,LTD.
+86-371-66670886 China 21032 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 22607 55
Hangzhou FandaChem Co.,Ltd.
+86-571-56059825 CHINA 8882 55
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 China 3001 55
career henan chemical co
+86-371-86658258 CHINA 29961 58
+86 18953170293
+86 0531-67809011 CHINA 2858 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114 CHINA 6369 58
Hubei xin bonus chemical co. LTD
027-59338440 CHINA 23035 58

View Lastest Price from Ethyl isocyanate manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-09-24 Ethyl isocyanate
US $0.00 / KG 1g 98%minGC 10Tons/month Shanghai Rlavie Technology Co ltd
2020-02-27 Ethyl Isocyanate
US $0.00 / kg 180kg 99% 1000MT Hefei TNJ Chemical Industry Co.,Ltd.
2019-07-06 Ethyl isocyanate
US $7.00 / kg 1kg 99% 100KG career henan chemical co

Ethyl isocyanate Spectrum

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