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L-Valine

Amino acids Content Analysis Chemical property Uses
L-Valine
L-Valine
CAS No.
72-18-4
Chemical Name:
L-Valine
Synonyms
L-VLA;Valin;L-Val;VALINE;2,3-D2);H-VAL-OH;L-VALINE;L-Val-OH;NSC 76038;VALINE, L-
CBNumber:
CB3381690
Molecular Formula:
C5H11NO2
Formula Weight:
117.15
MOL File:
72-18-4.mol

L-Valine Properties

Melting point:
295-300 °C (subl.)(lit.)
alpha 
28 º (c=8, 6N HCl)
Density 
1.23
refractive index 
28 ° (C=8, HCl)
storage temp. 
Store at RT.
solubility 
H2O: 25 mg/mL
form 
powder
pka
2.29(at 25℃)
color 
White
PH
5.5-6.5 (100g/l, H2O, 20℃)
optical activity
[α]20/D +27.0±0.5°, c = 5% in 5 M HCl
Water Solubility 
85 g/L (20 ºC)
λmax
λ: 260 nm Amax: 0.15
λ: 280 nm Amax: 0.1
Merck 
14,9909
BRN 
1721136
CAS DataBase Reference
72-18-4(CAS DataBase Reference)
NIST Chemistry Reference
Valine(72-18-4)

SAFETY

Hazard Codes  Xn
Risk Statements  40
Safety Statements  24/25-36-22
WGK Germany  3
RTECS  YV9361000
TSCA  Yes
HS Code  29224995

L-Valine price More Price(37)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 50848 L-Valine certified reference material, TraceCERT 72-18-4 100mg $95.2 2018-11-13 Buy
Sigma-Aldrich 1708503 L-Valine United States Pharmacopeia (USP) Reference Standard 72-18-4 200mg $401 2018-11-13 Buy
TCI Chemical V0014 L-Valine >98.0%(T) 72-18-4 25g $22 2018-11-22 Buy
TCI Chemical V0014 L-Valine >98.0%(T) 72-18-4 100g $64 2018-11-22 Buy
Alfa Aesar A12720 L-Valine, 99% 72-18-4 25g $26.7 2018-11-13 Buy

L-Valine Chemical Properties,Uses,Production

Amino acids

L-Valine is a kind of branched-chain amino acids (BCAA). Animal cannot synthesize it by itself. It must be obtained from the diet to meet their nutritional needs. Therefore L-valine belongs to the essential amino acids.
Amino acids are the basic structural unit of protein synthesis, and the predecessor of other amines that metabolism needs. They are indispensable materials in our life. At present, it is known that there are 20 to 30 amino acids. Some of them can be synthesized in the human body, which are known as non-essential amino acids. And some, called essential amino acids, cannot be synthesized in the human body that should be supplemented from the outside. Mammal cells need twelve essential amino acids: L-arginine, L-cystine, L-histidine, L-leucine, L-isoleucine, L-lysine, L-methionine, L-phenylalanine, L-threonine, L-tryptophan, L-tyrosine, L-valine. These amino acids are all laevoisomer, and some non-essential amino acids of dextroisomer may have inhibitory effect on cultured cells.
L-amino acids can easier to be absorbed than D-amino acids. And the absorption of D, L-methionine has no difference. There is competition between the body transport of amino acids. The transporting of an amino acid can be suppressed by the presence of another amino acid. For example, L-valine and L-methionine can inhibit the absorption of L-leucine. Excessive lysine in dietary can inhibit the absorption of arginine. High concentration (100mM) of L-valine has no effect on the absorption of L-methionine. Because it can be transported through another route.

Content Analysis

About 200mg sample is accurately weighed, dissolved in 3ml formic acid and 50ml glacial acetic acid. Add 2 drops of crystal violet test solution (TS-74), then use 0.1mol/L perchloric acid to titrate the solution to green or blue disappear entirely. Each Ml0.1mol/L perchloric acid is equivalent to 11.72mg L-valine (C5H11NO2).

Chemical property

White crystal or crystalline powder, odorless, bitter taste. Soluble in water, solubility in water of 8.85% at 25℃. Almost insoluble in ethanol, ether, acetone. melting point(decomposition point) 315℃, isoelectric point 5.96, [α]25D+28.3 (C = 1-2g/ml, in 5mol/L HCl).

Uses

  • Amino acids drugs, nutritional supplements. It can be used as the main component of aminophenol transfusion and synthesize aminophenol. L-Valine is one of the three branched-chain amino acids. It is essential amino acid. It can be used to treat liver failure and central nervous system dysfunction.
  • L-Valine is essential amino acid. The requirement for men is 10mg/(kg·d). Physiological effects of the L-form is 2 times of the D-type. L-Valine deficiency can cause neurological disorders, blastocolysis, loss of weight, anemia and the like. As nutritional supplements, it can be used to prepare aminophenol transfusion and synthesize aminophenol with other essential amino acid infusion. Valine added to metric pastry (1g/kg) can make the products aroma of sesame. L-Valine used in bread can also improve the flavor.
  • L-Valine is the essential amino acid. It can be used as one of pharmaceutical composition of amino acid infusion to synthesize drugs. It also can be used as food additives.
  • Nutritional supplements. It can be used to prepare aminophenol transfusion and synthesize aminophenol with other essential amino acid infusion.Valine added to metric pastry (1g/kg) can make the products aroma of sesame. L-Valine used in bread can also improve the flavor.
  • L-Valine can be used for biochemical research, the preparation of tissue culture media. It also used as amino acids nutritional drugs in medicine.

Chemical Properties

White or almost white, crystalline powder or colourless crystals, soluble in water, very slightly soluble in alcohol.

Uses

L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grai ns, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.

Uses

valine is an amino acid used as a skin-conditioning and odor-masking agent. It is more commonly used in hair care preparations than in skin care.

Definition

ChEBI: The L-enantiomer of valine.

Safety Profile

Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Purification Methods

Crystallise L-valine from water by addition of EtOH. It sublimes at 178-188o/0.03mm with 99.3% recovery and unracemised [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Perrin J Chm Soc 3125 1958, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2368-23771961, Beilstein 4 IV 2659.]

L-Valine Preparation Products And Raw materials

Raw materials

Preparation Products


L-Valine Suppliers

Global( 517)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 sales@capotchem.com China 19953 60
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22049 58
Shanghai Bojing Chemical Co.,Ltd.
+86-21-37122233
+86-21-37127788 Candy@bj-chem.com CHINA 500 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 663 60
Nanjing Finetech Chemical Co., Ltd.
025-85710122 17714198479
025-85710122 sales@fine-chemtech.com CHINA 894 55
ATK CHEMICAL COMPANY LIMITED
+86 21 5161 9050/ 5187 7795
+86 21 5161 9052/ 5187 7796 ivan@atkchemical.com CHINA 14293 60

View Lastest Price from L-Valine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-07-30 L-Valine
72-18-4
US $100.00 / KG 1KG 99% Customized career henan chemical co

L-Valine Spectrum


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