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Vecuronium bromide

Description References
Vecuronium bromide
Vecuronium bromide structure
CAS No.
50700-72-6
Chemical Name:
Vecuronium bromide
Synonyms
VBMC;nc-45;orgnc45;norcuron;Musculax;Muscurate;vecuronium;mide,diacetate;VECRONIUM BROMIDE;VECURONIUM BROMIDE
CBNumber:
CB3382859
Molecular Formula:
C34H57BrN2O4
Formula Weight:
637.73138
MOL File:
50700-72-6.mol

Vecuronium bromide Properties

Melting point:
227-229°C
alpha 
+30.5~+35.0゜(D/20℃)(c=0.5,dil.HCl)
storage temp. 
-20°C Freezer
solubility 
Slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in acetonitrile and in anhydrous ethanol.
form 
neat
Merck 
14,9941
BRN 
4837308
InChIKey
VEPSYABRBFXYIB-PWXDFCLTSA-M
CAS DataBase Reference
50700-72-6(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-22
Safety Statements  26-37/39
WGK Germany  3
RTECS  TN4875000
Toxicity LD50 in mice: 0.061 mg/kg i.v. (Buckett)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:

Vecuronium bromide price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 76904 Vecuronium bromide ≥97.0% (TLC) 50700-72-6 10mg $102 2018-11-20 Buy
Sigma-Aldrich 1711155 Vecuronium bromide United States Pharmacopeia (USP) Reference Standard 50700-72-6 50mg $352.8 2018-11-20 Buy
TCI Chemical V0120 Vecuronium Bromide Hydrate >98.0%(HPLC)(T) 50700-72-6 100mg $242 2018-11-22 Buy
Cayman Chemical 15603 Vecuronium (bromide) ≥98% 50700-72-6 50mg $96 2018-11-13 Buy
Cayman Chemical 15603 Vecuronium (bromide) ≥98% 50700-72-6 10mg $48 2018-11-13 Buy

Vecuronium bromide Chemical Properties,Uses,Production

Description

Vecuronium bromide (Brand name: Norcuron) is a drug which can be supplied to general anesthesia to keep skeletal muscle relaxation during the surgery or mechanical ventilation. It can also be used to help with endotracheal intubation. It has rapid onset (within 4 minutes) and has its effect last for 4 hour. Its mechanism of action is through competitively binding to the nicotinic cholinergic receptors, further antagonizing the opportunity for acetylcholine from binding to the nicotinic receptor at the postjunctional membrane of the myoneural junction. This process prevents the depolarization and the release of calcium ions, stopping muscle contraction and help muscle relaxation.

References

https://en.wikipedia.org/wiki/Vecuronium_bromide
https://www.drugbank.ca/drugs/DB01339  

Chemical Properties

White Solid

Uses

alcohol antagonist

Uses

An aminosteroid, competitive neuromuscular blocker agent.

Definition

ChEBI: The organic bromide salt of a 5alpha-androstane compound having 3alpha-acetoxy-, 17beta-acetoxy-, 2beta-piperidinino- and 16beta-N-methylpiperidinium su stituents.

brand name

Norcuron (Organon).

General Description

Vecuronium bromide, 1-(3 ,17 -dihydroxy-2 -piperidino-5 -androstan-16 -yl)-1-methylpiperidinium bromide diacetate (Norcuron), is themonoquaternary analog of pancuronium bromide. It belongsto the class of nondepolarizing neuromuscular blockingagents and produces effects similar to those of drugs in thisclass. It is unstable in the presence of acids and undergoesgradual hydrolysis of its ester functions in aqueous solution.Aqueous solutions have a pH of about 4.0.

Clinical Use

Vecuronium Bromide is usedmainly to produce skeletal muscle relaxation during surgeryand to assist in controlled respiration after general anesthesiahas been induced.

Vecuronium bromide Preparation Products And Raw materials

Raw materials

Preparation Products


Vecuronium bromide Suppliers

Global( 258)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3217 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 22043 58
Beijing Cooperate Pharmaceutical Co.,Ltd.
+86-10-60279497 +86(0)15646567669
+86-10-60279497 sales01@cooperate-pharm.com CHINA 1530 55
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20786 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32651 55
Chemwill Asia Co.,Ltd.
86-21-51086038
86-21-51861608 chemwill_asia@126.com;sales@chemwill.com;chemwill@hotmail.com;chemwill@gmail.com CHINA 24118 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 19997 58
Beijing Lianben Pharm-Chemicals Tech. Co., Ltd +86-10-83386766
+86-10-83386758 sales@lianben.com China 91 58
Beijing Xinze Pharmaceutical Technology Co., Ltd. 010-61393740
weihong_1979@163.com CHINA 48 58
Shanghai Boyle Chemical Co., Ltd. Mr Qiu:021-50182298(Demestic market) Miss Xu:021-50180596(Abroad market)
+86-21-57758967 sales@boylechem.com China 2220 55

View Lastest Price from Vecuronium bromide manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-08-20 Vecuronium bromide
50700-72-6
US $1.00 / KG 1G 98% 100KG career henan chemical co

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