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N-Acetyl-L-methionine

Identification Test Content Analysis Toxicity Grade Acute Toxicity Use Quantity
N-Acetyl-L-methionine
N-Acetyl-L-methionine structure
CAS No.
65-82-7
Chemical Name:
N-Acetyl-L-methionine
Synonyms
NAM;AC-MET-OH;methionin;N-AC-L-MET;Ac-L-Met-OH;AC-METHIONINE;N-ACETYL-L-MET;Ac-Met-OH NAM;Acetylmethionin;Acetylmethionine
CBNumber:
CB3394487
Molecular Formula:
C7H13NO3S
Formula Weight:
191.25
MOL File:
65-82-7.mol

N-Acetyl-L-methionine Properties

Melting point:
103-106 °C(lit.)
Boiling point:
235 °C(Press: 12 Torr)
alpha 
-20 º (c=4 H2O)
Density 
1.2684 (rough estimate)
refractive index 
-21 ° (C=1, H2O)
storage temp. 
Sealed in dry,Room Temperature
solubility 
methanol: soluble100mg/mL, clear, colorless
pka
3.50±0.10(Predicted)
optical activity
[α]20/D -21.0±1.0°, c = 1% in H2O
Merck 
14,96
BRN 
1725552
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
XUYPXLNMDZIRQH-LURJTMIESA-N
CAS DataBase Reference
65-82-7(CAS DataBase Reference)
FDA 21 CFR
172.372
Substances Added to Food (formerly EAFUS)
N-ACETYL-L-METHIONINE
FDA UNII
9J12WX5B6A
NIST Chemistry Reference
N-acetylmethionine(65-82-7)
EPA Substance Registry System
L-Methionine, N-acetyl- (65-82-7)
SAFETY
  • Risk and Safety Statements
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
RTECS  PD0480000
TSCA  Yes
HazardClass  IRRITANT
HS Code  29309070
NFPA 704
0
1 0

N-Acetyl-L-methionine price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 01310 N-Acetyl-L-methionine ≥98.5% (T) 65-82-7 5g $41.9 2020-08-18 Buy
Sigma-Aldrich 01310 N-Acetyl-L-methionine ≥98.5% (T) 65-82-7 25g $158 2020-08-18 Buy
TCI Chemical A2056 N-Acetyl-L-methionine >98.0%(HPLC)(T) 65-82-7 5g $15 2021-03-22 Buy
TCI Chemical A2056 N-Acetyl-L-methionine >98.0%(HPLC)(T) 65-82-7 25g $25 2021-03-22 Buy
Alfa Aesar B24312 N-Acetyl-L-methionine, 99% 65-82-7 5g $38.8 2020-06-24 Buy

N-Acetyl-L-methionine Chemical Properties,Uses,Production

Identification Test

Take a sample of 250mg, get it dissolved it in 2.5ml isopropyl alcohol and get it diluted with water to 25ml. Take this liquid of 10ml and get it diluted with water to 100m1. Then take the liquid of 0.5,30 and 50μ1 after two dilutions. Drop it at the place with a distance of 2cm from the bottom edge of the thin-layer chromatographic plate. The plate is coated with silica gel (Namely, 20cm * 20cm Brinkman silica gel of 60.250nm, or the equivalent). In a sealed and balanced thin-layered chromatography expansion tank, The chromatography was splayed out by 10cm, and the developer was composed of n-butanol and the mixture of acetic acid and water in the proportion 75:20=20.

Dry the plate overnight. Then spray the chromatography plate with a new iodoplatinate solution mixed with 10 percent chloroplatinic acid of 3ml, water of 97ml and 6 percent potassium iodide solution of 100ml. The sample shall be formed - a separate color spot with a Rf value of 0.67~0.1

Content Analysis

Weigh accurately about 250mg sample and put it in a flask with glass stopper. Add 100ml water, 5g dipotassium hydrogen phosphate, 2g potassium dihydrogen phosphate and 2g potassium iodide. Get it fully mixed and dissolved, plus 0. 1mol/L iodine solution of 50.0m1. Then stopper it and blend it. Leave it stand for 30 minutes and titrate excess iodine with 0.1mol / L sodium thiosulfate. Meanwhile conduct blank titration experiment. Iodine solution per Ml 0.1mol/L equals to this product (C7H13NO3S) 9.563mg.

Toxicity Grade

Safe for food(FDA,§172.372,2000).

Acute Toxicity

Vein - mouse LD50: 435 mg / kg

Use Quantity

Account for 3.1% of the total protein content in food (Calculated by free L- methionine).
It shall not be used for infant food and food containing adding nitrite / nitrate (FDA, 172.3722000).

Chemical Properties

white crystals

Definition

ChEBI: An L-methionine derivative that is L-methionine in which one of the amine hydrogens is substituted by an acetyl group.

Safety Profile

Poison by intravenous route. When heated to decomposition emits toxic fumes of NOX,.

Purification Methods

Crystallise N-acetyl-L-methionine from Me2CO, H2O or EtOAc. Dry it in a vacuum over P2O5. Its solubility at 25o in H2O is 30.7%, and in Me2CO it is 29.5%. [Mitzi & Schueter Biochim Biophys Acta 27 168 1958, Birnbaum et al. J Biol Chem 194 455 1952, Beilstein 4 IV 3206.]

N-Acetyl-L-methionine Preparation Products And Raw materials

Raw materials

Preparation Products


N-Acetyl-L-methionine Suppliers

Global( 298)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan DaKen Chemical CO.,LTD.
+86-371-66670886
info@dakenchem.com China 20914 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 22607 55
Shanghai Yingrui Biopharma Co., Ltd.
+86-21-33585366 E-mail:sales03@shyrchem.com
+86-21-34979012 sales03@shyrchem.com CHINA 739 60
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 29954 58
NINGBO INNO PHARMCHEM CO., LTD.
13867897135
sales@nbinno.com CHINA 925 58
Hubei Jusheng Technology Co.,Ltd.
86-18871470254
027-59599243 linda@hubeijusheng.com CHINA 28229 58
Accela ChemBio Inc.
(+1)-858-699-3322
(+1)-858-876-1948 info@accelachem.com United States 19969 58
Hebei Guanlang Biotechnology Co., Ltd.
+8619930503282
sales3@crovellbio.com China 5892 58
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6369 58
Hubei xin bonus chemical co. LTD
86-13657291602
027-59338440 linda@hubeijusheng.com CHINA 23035 58

View Lastest Price from N-Acetyl-L-methionine manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2021-10-21 N-acetyl-L-methionine
65-82-7
US $5.00-150.00 / KG 1KG >99% 20tons Anhui Rencheng Technology Co., Ltd
2021-09-29 N-Acetyl-L-methionine
65-82-7
US $0.00 / Kg/Drum 1KG 99%-100.5% AJI 1000kg WUHAN FORTUNA CHEMICAL CO., LTD
2021-08-26 N-Acetyl-L-Methionine
65-82-7
US $5.70 / Kg/Bag 10g 99% 10000kg Hebei Crovell Biotech Co Ltd

N-Acetyl-L-methionine Spectrum


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