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5-BROMOTHIOPHENE-2-CARBONITRILE

5-BROMOTHIOPHENE-2-CARBONITRILE structure

CAS No.: 2160-62-5

Chemical Name:: 5-BROMOTHIOPHENE-2-CARBONITRILE

Synonyms: 5-BROMOTHIOPHENE-2-CAR;2-Bromo-5-cyanothiophene;2-Cyano-5-bromothiophene;2-Bromo-5-cyanothiophene>5-BroMothiophene-2-carbon...;5-Bromo-2-Thiophenecarbonitrile;5-BROMOTHIOPHENE-2-CARBONITRILE;5-Bromothiophene-2-acetonitrile;2-Thiophenecarbonitrile,5-broMo-;5-Brono-thiophene-2-carbonitrile

CBNumber:: CB3397817

Molecular Formula:: C5H2BrNS

Molecular Weight:: 188.05

MDL Number:: MFCD04974080

MOL File:: 2160-62-5.mol

MSDS File:: SDS

Last updated:2025-08-18 19:12:29

Product description	Number	Pack Size	Price
5-Bromothiophene-2-carbonitrile 97%	574430	1g	$52.08
2-Bromo-5-cyanothiophene >97.0%(GC)	B4204	1g	$135
5-Bromothiophene-2-carbonitrile	B698980	100mg	$45
2-Cyano-5-bromothiophene	FC54142	500mg	$50
5-Bromothiophene-2-carbonitrile 97%	P000265642	1g	$25
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5-BROMOTHIOPHENE-2-CARBONITRILE Properties

Boiling point	124°C/34mmHg(lit.)
Density	1.694 g/mL at 25 °C (lit.)
refractive index	n20/D 1.6190(lit.)
Flash point	214 °F
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	clear liquid
color	Colorless to Light orange to Yellow
Specific Gravity	1.619
λmax	276nm(Benzene)(lit.)
InChI	InChI=1S/C5H2BrNS/c6-5-2-1-4(3-7)8-5/h1-2H
InChIKey	YVVHCBNJWHPMCQ-UHFFFAOYSA-N
SMILES	C1(C#N)SC(Br)=CC=1
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332-H315-H319-H335
Precautionary statements	P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	26-36/37
RIDADR	3267
WGK Germany	3
HS Code	29309090

5-BROMOTHIOPHENE-2-CARBONITRILE price More Price(43)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	574430	5-Bromothiophene-2-carbonitrile 97%	2160-62-5	1g	$52.08	2025-07-31	Buy
TCI Chemical	B4204	2-Bromo-5-cyanothiophene >97.0%(GC)	2160-62-5	1g	$135	2023-01-07	Buy
TRC	B698980	5-Bromothiophene-2-carbonitrile	2160-62-5	100mg	$45	2021-12-16	Buy
Biosynth Carbosynth	FC54142	2-Cyano-5-bromothiophene	2160-62-5	500mg	$50	2021-12-16	Buy
Ark Pharm	P000265642	5-Bromothiophene-2-carbonitrile 97%	2160-62-5	1g	$25	2021-12-16	Buy

Product number	Packaging	Price	Buy
574430	1g	$52.08	Buy
B4204	1g	$135	Buy
B698980	100mg	$45	Buy
FC54142	500mg	$50	Buy
P000265642	1g	$25	Buy

5-BROMOTHIOPHENE-2-CARBONITRILE Chemical Properties,Uses,Production

Chemical Properties

Colorless liquid or semisolid

Synthesis

2160-63-6

2160-62-5

General procedure for the synthesis of 5-bromothiophene-2-carboxaldehyde oxime from 5-bromothiophene-2-carbonitrile: To a mixture of 5-bromothiophene-2-carboxaldehyde oxime (1.3 g, 6.2 mmol) and tetrahydrofuran (15 mL), acetic acid (1.4 mL, 25 mmol) and acetic anhydride (1.5 mL, 15 mmol) were added, and the reaction was started at room temperature. Subsequently, the reaction mixture was stirred at 50 °C for 2 hours, then warmed to 70 °C to continue stirring for 8 hours. Upon completion of the reaction, the reaction mixture was cooled and the solvent was removed by vacuum concentration. The crude product was purified by NH-silica gel column chromatography (eluent ratio heptane:ethyl acetate=8:1) to afford 5-bromothiophene-2-carbonitrile (1.0 g, 5.4 mmol, 88% yield) as a colorless solid.1H-NMR (CDCl3) δ (ppm): 7.11 (1H, d, J=4.0 Hz), 7.40 (1H, d, J=4.0 Hz).

References

[1] Patent: EP1782811, 2007, A1. Location in patent: Page/Page column 51
[2] Bulletin de la Societe Chimique de France, 1967, p. 4115 - 4120
[3] Patent: WO2003/87103, 2003, A1. Location in patent: Page/Page column 17
[4] Patent: WO2005/82899, 2005, A1. Location in patent: Page/Page column 30
[5] Synlett, 2011, # 15, p. 2223 - 2227

5-BROMOTHIOPHENE-2-CARBONITRILE Preparation Products And Raw materials

Raw materials

1,1'-Carbonyldiimidazole Sodium acetate 2-Thiophenecarboxylic acid Acetic anhydride N,N-Dimethylformamide

Bromine Acetic acid 2-Thiophenecarboxaldehyde, 5-bromo-, oxime, [C(Z)]- 5-Bromothiophene-2-carbaldehyde 2-Thiophenecarbonitrile

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Preparation Products

Thiophene-2,5-dicarbonitrile 5-(METHYLTHIO)THIOPHENE-2-CARBONITRILE

5-BROMOTHIOPHENE-2-CARBONITRILE Suppliers

Global( 174)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-13017695106 +86-13676922317	jiuyitime@fdachem.com	China	16515	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29735	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	figo.gao@foxmail.com	China	8497	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
Yunbio Tech Co.,Ltd.	+86-010-60605551 +86-18046518538	yunbiochem@126.com	China	321	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29798	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	+8613580539051	joe@yuhengpharm.com	CHINA	21142	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Jinan Carbotang Biotech Co.,Ltd.	58
Accela ChemBio Inc.	58
Yunbio Tech Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd	58

View Lastest Price from 5-BROMOTHIOPHENE-2-CARBONITRILE manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-10-13	5-Bromothiophene-2-carbonitrile 2160-62-5	US $1.10-9.90 / KG	1KG	99% min	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
2025-07-25	5-BROMOTHIOPHENE-2-CARBONITRILE 2160-62-5	US $0.00 / kg	1kg	98%	1000kg	Shaanxi Dideu New Materials Co. Ltd
2021-07-13	5-BROMOTHIOPHENE-2-CARBONITRILE 2160-62-5	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

5-Bromothiophene-2-carbonitrile
2160-62-5
US $1.10-9.90 / KG
99% min
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

5-BROMOTHIOPHENE-2-CARBONITRILE
2160-62-5
US $0.00 / kg
98%
Shaanxi Dideu New Materials Co. Ltd

5-BROMOTHIOPHENE-2-CARBONITRILE
2160-62-5
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

5-BROMOTHIOPHENE-2-CARBONITRILE Spectrum

5-BROMOTHIOPHENE-2-CARBONITRILE(2160-62-5)¹HNMR

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