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N1-(3-Aminophenyl)acetamide

N1-(3-Aminophenyl)acetamide structure

CAS No.: 102-28-3

Chemical Name:: N1-(3-Aminophenyl)acetamide

Synonyms: META AMINO ACETANILIDE;N-(3-AMINOPHENYL)ACETAMIDE;3-AMINOACETANILIDE;FR-2203;AKOS BB-8162;WLN: ZR CMV1;ASISCHEM B52481;3-AcetamidoaniL;3-aminoacetanilid;m-acetaminoaniline

CBNumber:: CB3404737

Molecular Formula:: C8H10N2O

Molecular Weight:: 150.18

MDL Number:: MFCD00025229

MOL File:: 102-28-3.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:42

Product description	Number	Pack Size	Price
3′-Aminoacetanilide 97%	485055	250g	$163
3'-Aminoacetanilide >98.0%(HPLC)(T)	A1533	25g	$27
N-(3-Aminophenyl)acetamide	A638140	25g	$75
N-(3-Aminophenyl)acetamide	A638140	2.5g	$45
3'-Aminoacetanilide	FA137386	100g	$50
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N1-(3-Aminophenyl)acetamide Properties

Melting point	86-88 °C(lit.)
Boiling point	271.72°C (rough estimate)
Density	1.1392 (rough estimate)
refractive index	1.6180 (estimate)
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
pka	14.82±0.70(Predicted)
form	powder to crystal
color	White to Gray to Brown
Water Solubility	1-5 g/100 mL at 24 ºC
InChI	InChI=1S/C8H10N2O/c1-6(11)10-8-4-2-3-7(9)5-8/h2-5H,9H2,1H3,(H,10,11)
InChIKey	PEMGGJDINLGTON-UHFFFAOYSA-N
SMILES	C(NC1=CC=CC(N)=C1)(=O)C
CAS DataBase Reference	102-28-3(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	Q5K7HYS7JJ
EPA Substance Registry System	3'-Aminoacetanilide (102-28-3)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-37/39

WGK Germany

RTECS

AD8050000

TSCA

Yes

HazardClass

IRRITANT

HS Code

29214200

Toxicity

mouse,LD50,intravenous,320mg/kg (320mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#02899,

NFPA 704

	1
2		0

N1-(3-Aminophenyl)acetamide price More Price(26)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	485055	3′-Aminoacetanilide 97%	102-28-3	250g	$163	2023-06-20	Buy
TCI Chemical	A1533	3'-Aminoacetanilide >98.0%(HPLC)(T)	102-28-3	25g	$27	2025-07-31	Buy
TRC	A638140	N-(3-Aminophenyl)acetamide	102-28-3	25g	$75	2021-12-16	Buy
TRC	A638140	N-(3-Aminophenyl)acetamide	102-28-3	2.5g	$45	2021-12-16	Buy
Biosynth Carbosynth	FA137386	3'-Aminoacetanilide	102-28-3	100g	$50	2021-12-16	Buy

Product number	Packaging	Price	Buy
485055	250g	$163	Buy
A1533	25g	$27	Buy
A638140	25g	$75	Buy
A638140	2.5g	$45	Buy
FA137386	100g	$50	Buy

N1-(3-Aminophenyl)acetamide Chemical Properties,Uses,Production

Chemical Properties

light brown crystalline powder

Uses

3'-Aminoacetanilide is mainly used as reaction intermediates dyes and disperse dyes.

General Description

Gray solid.

Air & Water Reactions

Soluble in water.

Reactivity Profile

Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition N1-(3-Aminophenyl)acetamide emits toxic fumes.

Fire Hazard

Flash point data concerning N1-(3-Aminophenyl)acetamide are not available, however, N1-(3-Aminophenyl)acetamide is probably combustible.

Synthesis

122-28-1

102-28-3

m-Nitroacetanilide (1 g, 5.66 mmol) was dissolved in 100 mL of methanol and a catalytic amount of 10% palladium/activated charcoal (~0.015 g) was added. The reaction mixture was cooled via an ice bath and sodium borohydride (1 g, 26.43 mmol) was added in batches. Subsequently, the mixture was stirred vigorously for 1 hour. The reaction process was monitored by thin layer chromatography (TLC) using toluene-acetone (5:2, v/v) as unfolding agent. Upon completion of the reaction, the product was purified by silica gel column chromatography with toluene-acetone (5:2, v/v) as eluent. A white solid product was obtained in 75% yield with a melting point of 86-88 °C. Elemental analysis (C8H10N2O, Mr=150.18) Calculated values: C 63.98%, H 6.71%, N 18.65%; measured values: C 63.76%, H 6.50%, N 18.53%.1H NMR (400 MHz, DMSO-d6) δ: 9.58 (s, 1H, NH), 6.92 (t, 1H, H-2, J = 2.00 Hz), 6.88 (t, 1H, H-4, J = 8.00 Hz), 6.64 (dd, 1H, H-6, J1 = 0.80 Hz, J2 = 8.00 Hz), 6.23 (dd, 1H, H-5, J1 = 1.60 Hz, J2 = 8.00 Hz), 5.00 (bs, 2H, NH2), 1.99 (s, 3H , CH3-CO).13C NMR (100 MHz, DMSO-d6) δ: 167.85 (C=O), 148.85 (C1), 139.85 (C3), 128.75 (C4), 109.04 (C5), 106.93 (C6), 104.67 (C2), 23.98 (CH3-CO).

References

[1] Green Chemistry, 2018, vol. 20, # 1, p. 130 - 135
[2] Supramolecular Chemistry, 2010, vol. 22, # 10, p. 586 - 597
[3] Bioorganic Chemistry, 2014, vol. 57, p. 13 - 29
[4] Chemical & Pharmaceutical Bulletin, 1989, vol. 37, # 3, p. 615 - 617
[5] Journal of Chemical Research, 2006, # 4, p. 223 - 224

N1-(3-Aminophenyl)acetamide synthesis

Synthesis of N1-(3-Aminophenyl)acetamide from m-Phenylenediamine and p-Phenylenediamine

N1-(3-Aminophenyl)acetamide Preparation Products And Raw materials

Raw materials

CALCIUM SULFIDE m-Phenylenediamine Acetic acid 3-Nitroaniline Ethanone, 1-(3-aminophenyl)-, oxime (9CI)

3'-NITROACETANILIDE 3'-AMINOACETANILIDE HYDROCHLORIDE OPD EASY-tablets p-Phenylenediamine Ethyl acetate

Sodium acetate 3'-CHLOROACETANILIDE 4'-Nitroacetanilide Acetic anhydride

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Preparation Products

Acid Blue BGL Reactive Golden Yellow KM-G trisodium 7-[[2-[(aminocarbonyl)amino]-4-[(4-amino-6-chloro-1,3,5-triazin-2-yl)amino]phenyl]azo]naphthalene-1,3,5-trisulphonate Reactive Yellow 3 Reactive Yellow KE-RN

3,6-diamino-9(10)-acridone 3-ACETAMIDOPHENOL Aniline C.I. Acid Red 23, disodium salt 2,7-Naphthalenedisulfonic acid, 3-[(4-aminophenyl)azo]-4-hydroxy-5-[[(4-methylphenyl)sulfonyl]amino]-, disodium salt

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N1-(3-Aminophenyl)acetamide Suppliers

Global( 401)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8618531123677	faithe@yan-xi.com	China	5853	58
Hebei Chuanghai Biotechnology Co,.LTD	+86-13131129325	sales1@chuanghaibio.com	China	5250	58
Hebei Chuanghai Biotechnology Co., Ltd	+8615531151365	mina@chuanghaibio.com	China	18126	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21615	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3009	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29850	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
Xiamen AmoyChem Co., Ltd	+86-86-5926051114 +8615060885618	sales@amoychem.com	China	6369	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Chuanghai Biotechnology Co,.LTD	58
Hebei Chuanghai Biotechnology Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
career henan chemical co	58
Hubei Jusheng Technology Co.,Ltd.	58
Xiamen AmoyChem Co., Ltd	58
Hubei xin bonus chemical co. LTD	58
Alchem Pharmtech,Inc.	58

View Lastest Price from N1-(3-Aminophenyl)acetamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-06-27	N1-(3-Aminophenyl)acetamide 102-28-3	US $0.00-0.00 / KG	50KG	99%	500000kg	Hebei Chuanghai Biotechnology Co., Ltd
2025-06-20	N1-(3-Aminophenyl)acetamide 102-28-3	US $0.00 / kg	1kg	0.99	20tons	Hebei Yanxi Chemical Co., Ltd.
2025-05-26	3-Acetamidoaniline 102-28-3	US $5.00-2.00 / KG	1KG	99%	10000kg	Hebei Chuanghai Biotechnology Co,.LTD

N1-(3-Aminophenyl)acetamide
102-28-3
US $0.00-0.00 / KG
99%
Hebei Chuanghai Biotechnology Co., Ltd

N1-(3-Aminophenyl)acetamide
102-28-3
US $0.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

3-Acetamidoaniline
102-28-3
US $5.00-2.00 / KG
99%
Hebei Chuanghai Biotechnology Co,.LTD

N1-(3-Aminophenyl)acetamide Spectrum

N1-(3-Aminophenyl)acetamide(102-28-3)MS N1-(3-Aminophenyl)acetamide(102-28-3)¹HNMR N1-(3-Aminophenyl)acetamide(102-28-3)IR1 N1-(3-Aminophenyl)acetamide(102-28-3)IR2

102-28-3(N1-(3-Aminophenyl)acetamide)Related Search:

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N-(3-Nitro-Phenyl)-3-Oxo-Butyramide N,N'-1,3-Phenylene bismaleimide ALPHA-CHLORO-3-NITROACETANILIDE 3-Hydroxy-N-(3-nitrophenyl)-2-naphthalenecarboxamide 3'-NITROACETANILIDE

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3'-AMINOACETANILIDE HYDROCHLORIDE N-(2-Methoxy-4-aminophenyl)acetamide 4'-Aminoacetanilide

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3’-amino-acetanilid 3-acetylaminoaniline 3-aminoacetanilid Acetyl-m-phenylenediamine m-acetaminoaniline n-(3-aminophenyl)-acetamid n-acetyl-m-fenylendiamin N-ACETYL-M-PHENYLENEDIAMINE N-ACETYL-1,3-PHENYLENEDIAMINE N1-(3-AMINOPHENYL)ACETAMIDE TIMTEC-BB SBB008515 1-ACETAMIDO-3-AMINOBENZENE 3-ACETAMIDOANILINE AKOS BB-8162 ART-CHEM-BB B017800 ASISCHEM B52481 M-ACETYLAMINOANILINE M-ACETAMIDOANILINE M-AMINOACETANILIDE 3-Aminoacetanilide HCl Acetamide, N-(3-aminophenyl)- (9CI) N-Acetyl-3-phenylenediaminehydrochloride 3-AMINOACETANILINE N-ACETYL-META-PHENYLENEDIAMINE 3'-Aminoacetanilide,98% 3-AcetaMidoanilide 3-Acetamidoaniline N-Acetyl-1,3-phenylenediamine N-(3-Aminophenyl)acetamide, 3-Acetamidoaniline Between aMino acetanilide 1-Amino-3-(acetylamino)benzene 3-Aminoacetanilid [Czech] 3-Amino-N-acetylaniline Acetamide, N-(3-aminophenyl)- Acetanilide, 3'-amino- FR-2203 N-(3-aminophenyl)ethanamide N-Acetyl-m-fenylendiamin [Czech] N-Acetyl-m-fenylenediamin WLN: ZR CMV1 3-AcetamidoaniL Meta Amino Acetanilide (MAA) m-acetamide aniline 3'-Aminoacetanilide > N1-(3-Aminophenyl)acetamide ISO 9001：2015 REACH N-(3-AMINOPHENYL)ACETAMIDE 3-AMINOACETANILIDE META AMINO ACETANILIDE META AMINO ACETANILID 3-AMINO ACETANILIDE (MAA) M-AMINOACETANILIDE (MAA) 3'-Aminoacetanilide Trametinib Impurity 26 N1-(3 minophenyl)acetamide 102-28-3 NH2C6H4NHCOCH3 Building Blocks Protected Amines Organic Building Blocks