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BAPTA

BAPTA Structure
BAPTA structure
CAS No.
85233-19-8
Chemical Name:
BAPTA
Synonyms
BAPTA;CS-2002;BAPTA,97%;BAPTA, >=98%;BAPTA, Free Acid;BAPTA, 10 mM in DMSO;85233-19-8(free acid);BAPTA, extracellular calcium chelator;1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N',N'- TETRAACETI;ETHYLENEDIOXYBIS(O-PHENYLENENITRILO)TETRAACETIC ACID
CBNumber:
CB3406887
Molecular Formula:
C22H24N2O10
Molecular Weight:
476.43
MDL Number:
MFCD00036255
MOL File:
85233-19-8.mol
MSDS File:
SDS
Last updated:2025-10-27 16:32:13
Product description Number Pack Size Price
1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) 14510 100MG $62.37
1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) 14510 250MG $105.5
1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) 14510 1G $263
1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) 14510 50G $3620
1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid >97.0%(HPLC) B3895 1g $134
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BAPTA Properties

Melting point 177-179 °C
Boiling point 575.89°C (rough estimate)
Density 1.4482 (rough estimate)
refractive index 1.6500 (estimate)
RTECS MC0423000
storage temp. 2-8°C
solubility Soluble in dimethyl sulfoxide
form Powder
pka 1.40±0.10(Predicted)
color White to off-white
Appearance Solid Powder
Water Solubility Soluble in water and sodium bicarbonate.
λmax 209 nm, 254 nm, 203 nm, 274 nm
Merck 14,957
BRN 5192406
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Biological Applications Calcium indicators; zinc indicators; treating acute cell death,cerebral infarction,myocardial infarction,hepatonecrosis,kidney ischemic necrosis,necrotizing pancreatitis,amyloidosis,atherosclerosis,diseases characteriz
InChIKey FTEDXVNDVHYDQW-UHFFFAOYSA-N
CAS DataBase Reference 85233-19-8(CAS DataBase Reference)
FDA UNII K22DDW77C0
UNSPSC Code 12352112
NACRES NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
HS Code  29225090
NFPA 704
1
2 0

BAPTA price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 14510 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) 85233-19-8 100MG $62.37 2025-07-31 Buy
Sigma-Aldrich 14510 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) 85233-19-8 250MG $105.5 2025-07-31 Buy
Sigma-Aldrich 14510 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) 85233-19-8 1G $263 2025-07-31 Buy
Sigma-Aldrich 14510 1,2-Bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid ≥96.0% (HPLC) 85233-19-8 50G $3620 2025-07-31 Buy
TCI Chemical B3895 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid >97.0%(HPLC) 85233-19-8 1g $134 2025-07-31 Buy
Product number Packaging Price Buy
14510 100MG $62.37 Buy
14510 250MG $105.5 Buy
14510 1G $263 Buy
14510 50G $3620 Buy
B3895 1g $134 Buy

BAPTA Chemical Properties,Uses,Production

Description

BAPTA free acid (85233-19-8) is a selective extracellular Ca2+ chelator. It is a widely used calcium sponge for chelating Ca2+?outside of intact cells.1 It’s a useful tool to probe the involvement of extracellular Ca2+ in cellular signaling.2,3 Non-cell-permeable.

Chemical Properties

White Solid

Uses

As calcium chelator; 19F labelled forms for measurement of intracellular calcium.

Uses

BAPTA is a highly selective calcium chelating reagent. Lipophilic diesters of the chelating agent 1,2-Bis(2 aminophenoxy)ethane-N,N,N',N'-tetraacetic acid (BAPTA) are used for inhibition of proteolytic activities of certain metalloproteinases, calpain and TACE.

Uses

Highly selective calcium chelating reagent. Suitable for the spectrophotometric monitoring of Ca2+ levels.

Definition

ChEBI: A polyamino carboxylic acid in which bis(carboxymethyl)nitrilo groups are bonded to C-2 and C-2' of 1,1'-[ethane-1,2-diylbis(oxy)]dibenzene.

General Description

In nature 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetra acetic acid (BAPTA) is a main metabolic product of BAPTA -AM (BAPTA-tetra(actoxymethyl ester), a neuro protective agent in cerebral ischemia, in rats.BAPTA is an intercellular Ca2+ chelator.

Biological Activity

Selective calcium chelator.

storage

Store at +4°C

References

[1] ALBERTO MUÑOZ. Different Stress-Induced Calcium Signatures Are Reported by Aequorin-Mediated Calcium Measurements in Living Cells of Aspergillus fumigatus.[J]. PLoS ONE, 2015: e0138008. DOI:10.1371/journal.pone.0138008
[2] K. WOZNIAK. Extracellular Ca2+ Is Required for Fertilization in the African Clawed Frog, Xenopus laevis[J]. PLoS ONE, 2017. DOI:10.1371/journal.pone.0170405
[3] MIROSLAVA DIDIASOVA. STIM1/ORAI1-mediated Ca2+ Influx Regulates Enolase-1 Exteriorization.[J]. The Journal of Biological Chemistry, 2015: 11983-11999. DOI:10.1074/jbc.m114.598425

BAPTA Preparation Products And Raw materials

Raw materials

Sodium dithionite Ammonium hydroxide Hydrazinium hydroxide solution Acetonitrile Ethanol
N,N-Dimethylformamide 2-Nitrophenol N,N-Diisopropylethylamine Palladium Sodium iodide
Ethyl bromoacetate 1,2-Dibromoethane Hydrochloric acid Hydrogen Dichloromethane
Acetic acid Methanol Sodium hydroxide

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Preparation Products

BAPTA Suppliers

Global( 220)Suppliers
Supplier Tel Email Country ProdList Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		+86-13017695106 +86-13676922317 jiuyitime@fdachem.com China 16514 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29798 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
Hefei Hirisun Pharmatech Co., Ltd 		+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Labnetwork lnc. 		+86-27-50766799 +8618062016861 contact@labnetwork.com China 19987 58
Alfa Chemistry 		+1-5166625404; Info@alfa-chemistry.com United States 20405 58
Supplier Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD 		58
Capot Chemical Co.,Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
TargetMol Chemicals Inc. 		58
Hefei Hirisun Pharmatech Co., Ltd 		58
Labnetwork lnc. 		58
Alfa Chemistry 		58

View Lastest Price from BAPTA manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
BAPTA pictures 2025-10-27 BAPTA
85233-19-8
 US $90.00-50.00 / mg 96.28% 10g TargetMol Chemicals Inc.
BAPTA pictures 2025-10-13 BAPTA
85233-19-8
 US $2.20-8.80 / kg 1kg 99%min 100kg ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
1,2-Bis(2-Aminophenoxy)ethane-N,N,N 2021-07-02 1,2-Bis(2-Aminophenoxy)ethane-N,N,N",N"-tetraacetic acid 98%
85233-19-8
 US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
  • BAPTA pictures
  • BAPTA
    85233-19-8
  • US $90.00-50.00 / mg
  • 96.28%
  • TargetMol Chemicals Inc.
  • BAPTA pictures
  • BAPTA
    85233-19-8
  • US $2.20-8.80 / kg
  • 99%min
  • ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

BAPTA Spectrum

BAPTA(85233-19-8)1HNMR

85233-19-8(BAPTA)Related Search:

RHOD-2, AM BAPTA BAPTA-AM Fura 2-AM Fluo 3-AM
BAPTA TETRASODIUM SALT HYDRATE, 98+%,BAPTA-NA4,BAPTA, TETRASODIUM SALT BAPTA, 5,5'-DIBROMO-, TETRASODIUM SALT,5,5'-DIBROMO-BAPTA BAPTA POTASSIUM,BAPTA TETRAPOTASSIUM SALT,BAPTA(K+ SALT),BAPTA 4K BAPTA TETRAETHYL ESTER,BAPTA TETRAETHYL ESTER, 98+% FURA 2 PENTAPOTASSIUM SALT
FURA 2 1-[2-(5-CARBOXYOXAZOL-2-YL)-6-AMINOBENZOFURAN-5-OXY]-2-(2'-AMINO-5'-METHYLPHENOXY)-ETHANE-N,N,N',N'-TETRAACETIC ACID, 5NA FLUO 3 INDO 1-AM NITR 5/AM
INDO 1 PENTAPOTASSIUM SALT BAPTA, TETRACESIUM SALT BAPTA-TMFM

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BAPTA ETHYLENEDIOXYBIS(O-PHENYLENENITRILO)TETRAACETIC ACID 1,2-BIS-(O-AMINOPHENOXY)-ETHANE-N,N,N',N'-TETRAACETIC ACID BAPTA, Ethylenedioxybis(o-phenylenenitrilo)tetraacetic acid, 2,2μ-(Ethylenedioxy)dianiline-N,N,Nμ,Nμ-tetraacetic acid BAPTA, Ethylenedioxybis(o-phenylenenitrilo)tetraacetic acid 1,2-BIS(2-AMINOPHENOXY)-ETHANE-N,N,N',N'- TETRAACETIC ACID 97% 2,2',2'',2'''-[Ethylenebisoxybis(2,1-phenylenenitrilo)]tetrakisacetic acid Ethylenebis(oxy-2,1-phenylenenitrilo)tetraacetic acid 1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N',N'- TETRAACETI 1,2-Bis-(2-Aminophenoxy) Ethane-N,N,N,-Tetra Acetic Acid BAPTA (1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N'',N'' -TETRAACETIC ACID) N,N'-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxyMethyl)glycine Glycine, N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxyMethyl)- 1,2-Bis(2-aMinophenoxy)ethane-N,N,N',N'-tetraacetic acid >=96.0% (HPLC) BAPTA, >=98% 2,2'-((2-(2-(3-(Bis(carboxymethyl)amino)phenoxy)-ethoxy)phenyl)azanediyl)diacetic acid 1,2-bis(2-aminophenoxy)ethane-n,n,n0, n0-tetraacetic Acid 1,2-bis(o-aminophenoxy)ethane-n,n, n0,n0-tetraacetic Acid 2,20-(ethylenedioxy)dianiline-n,n,n0, n0-tetraacetic Acid BAPTA, Free Acid 1,2-Bis(2-aminophenoxy)-ethane-N,N,N'N'-tetraacetic acid,97% BAPTA,97% CS-2002 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid > 1,2-Bis-(2-amino-phenoxy)ethane N,N,N',N'-tetraacetic 2-[2-[2-[2-[bis(carboxymethyl)amino]phenoxy]ethoxy]-N-(carboxymethyl)anilino]acetic acid 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic Acid 2,2',2'',2'''-(((Ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis(azanetriyl))tetraacetic acid Glycine,N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)- BAPTA, extracellular calcium chelator BAPTA, 10 mM in DMSO 1,2-Bis(2-Aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid 85233-19-8(free acid) 2,2',2'',2'''-(((Ethane-1,2-diylbis(oxy))bis(2,1-phenylene))bis(azanetriyl))tetraacetic acid 1,2-Bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid 85233-19-8 C22H24N2O10 C22H20N2O10 Detection Fluorescent Probes, Labels, Particles and Stains Intracellular Calcium Signaling Cell Signaling and Neuroscience Cell Biology Calcium Chelators Calcium Signaling Research Tools BioChemical Biochemicals and Reagents Aromatic Amines Aromatics Chelating Agents & Ligands Fluorescent Labels & Indicators