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N-OMEGA-PROPYL-L-ARGININE

CAS No.
137361-05-8
Chemical Name:
N-OMEGA-PROPYL-L-ARGININE
Synonyms
N-PLA;NΩZinc01546170;N-alpha,Nω-dimethyl-Nω-PROPYL-L-ARGININE;-bis-Boc-D-arginine;NW-PROPYL-L-ARGININE;NG-PROPYL-L-ARGININE;Nω-Propyl-L-Arginine
CBNumber:
CB3410297
Molecular Formula:
C9H20N4O2
Molecular Weight:
216.28
MDL Number:
MFCD01320455
MOL File:
137361-05-8.mol
MSDS File:
SDS
Last updated:2025-08-20 16:56:13
Product description Number Pack Size Price
Nω-Propyl-L-Arginine hydrochloride ≥98% (HPLC) SML2341 5mg $96.8
Nω-Propyl-L-Arginine hydrochloride ≥98% (HPLC) SML2341 25mg $220.5
Nω-propyl-L-Arginine ≥98% 80587 5mg $55
Nω-propyl-L-Arginine ≥98% 80587 10mg $101
Nω-propyl-L-Arginine ≥98% 80587 50mg $420

N-OMEGA-PROPYL-L-ARGININE Properties

Melting point 198-200?C
Boiling point 366.5±52.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. Desiccate at RT
solubility Chloroform (Slightly), Methanol (Slightly)
pka 2.50±0.24(Predicted)
form White to off-white solid.
color White
Stability Very Hygroscopic
CAS DataBase Reference 137361-05-8(CAS DataBase Reference)
FDA UNII G7F9U4R2AC

N-OMEGA-PROPYL-L-ARGININE price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML2341 Nω-Propyl-L-Arginine hydrochloride ≥98% (HPLC) 137361-05-8 5mg $96.8 2025-07-31 Buy
Sigma-Aldrich SML2341 Nω-Propyl-L-Arginine hydrochloride ≥98% (HPLC) 137361-05-8 25mg $220.5 2025-07-31 Buy
Cayman Chemical 80587 Nω-propyl-L-Arginine ≥98% 137361-05-8 5mg $55 2024-03-01 Buy
Cayman Chemical 80587 Nω-propyl-L-Arginine ≥98% 137361-05-8 10mg $101 2024-03-01 Buy
Cayman Chemical 80587 Nω-propyl-L-Arginine ≥98% 137361-05-8 50mg $420 2024-03-01 Buy
Product number Packaging Price Buy
SML2341 5mg $96.8 Buy
SML2341 25mg $220.5 Buy
80587 5mg $55 Buy
80587 10mg $101 Buy
80587 50mg $420 Buy

N-OMEGA-PROPYL-L-ARGININE Chemical Properties,Uses,Production

Description

Nω-Propyl-L-Arginine is a potent and selective inhibitor of neuronal nitric oxide synthase (nNOS). Nω-Propyl-L-Arginine is a competitive inhibitor of bovine nNOS having a Ki value of 57 nM. The Ki values for eNOS (bovine) and iNOS (murine) are 8.5 and 180 μM, respectively. Nω-propyl-L-Arginine therefore exhibits 3,000-fold and 150-fold selectivity for the neuronal isoform versus the inducible (murine) and endothelial (bovine) isoforms of NOS, respectively.

Chemical Properties

Off-White Solid

Uses

A highly selective competitive inhibitor and inactivator of all three isoforms of NOS.

Uses

Nω-Propyl-L-Arginine is a neuronal selective nitric oxide synthase inhibitor (1) and a highly selective competitive inhibitor and inactivator of all three isoforms of NOS (2,3).

Biological Activity

Highly selective and potent inhibitor of nNOS (K i = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo .

storage

room temperature (desiccate)

References

[1] HENRY Q. ZHANG. Potent and Selective Inhibition of Neuronal Nitric Oxide Synthase by Nω-Propyl-l-arginine[J]. Journal of Medicinal Chemistry, 1997, 40 24: 3869-3870. DOI: 10.1021/jm970550g

N-OMEGA-PROPYL-L-ARGININE Preparation Products And Raw materials

Raw materials

Preparation Products

N-OMEGA-PROPYL-L-ARGININE Suppliers

Global( 74)Suppliers
Supplier Tel Email Country ProdList Advantage
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49975 58
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
Career Henan Chemica Co
+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19908 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49946 58
Aladdin Scientific
tp@aladdinsci.com United States 52924 58
Mainchem Co., Ltd. +86-0592-6210733 sale@mainchem.com China 32343 55

View Lastest Price from N-OMEGA-PROPYL-L-ARGININE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Nω-Propyl-L-arginine pictures 2024-10-28 Nω-Propyl-L-arginine
137361-05-8
US $138.00-1050.00 / mg 10g TargetMol Chemicals Inc.
L-N5-(1-IMINO-9-PROPYLAMINO-O-METHYL)ORINTHINE L-N5-(1-IMINO(PROPYLAMINO))METHYL-ORNITHINE 2(S)-2-AMINO-5-(N-PROPYLGUANIDINO)PENTANOIC ACID N5-[IMINO(PROPYLAMINO)METHYL]-L-ORNITHINE NW-PROPYL-L-ARGININE N-PLA N-OMEGA-PROPYL-L-ARGININE NG-PROPYL-L-ARGININE N&OMEGA -PROPYL-L-ARGININE N-2-PROPYL-L-ARGININE Zinc01546170 N5-[Imino(propylamino)methyl]-L-ornithinehydrochloride Nω-Propyl-L-arginine hydrochloride N5-[IMino(propylaMino)Methyl]- -Propyl-L-arginine hydrochloride Nω-Propyl-L-Arginine -(2,2,4,6,7-Pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine methyl ester hydrochloride -(2,2,4,6,7-Pentamethyldihydro-benzofuran-5-sulfonyl)-L-arginine allyl ester hydrochloride -Hydroxy-nor-L-Arginine Dihydrochloride -Methyl-L-arginine hydrochloride -bis-Z-L-arginine N-hydroxysuccinimide ester -bis-Boc-D-arginine N-alpha,N&omega -Tris-Z-L-arginine N-hydroxysuccinimide ester -(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine -(di-tert-butyloxycarbonyl)-L-arginine cyclohexylammonium salt -(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine tert-butyl ester -(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine -dimethyl-N&omega -Hydroxy-L-arginine monoacetate -(2,2,5,7,8-Pentamethylchroman-6-sulfonyl)-D-arginine-2-chlorotrityl resin (S)-2-Amino-5-(3-propylguanidino)pentanoic acid -Nitro-D-arginine methyl ester hydrochloride L-Ornithine, N5-[imino(propylamino)methyl]- Nomega-Propyl-L-arginine hydrochloride Nomega-Propyl-L-arginine hydrochloride, neuronal nitric oxide synthase (nNOS) inhibitor Nomega-Propyl-L-arginine, neuronal nitric oxide synthase (nNOS) inhibitor N-ω-Propyl-L-arginine - Bio-X ? 137361-05-8 C9H20N4O2 C9H20N4O2HCl All Inhibitors Inhibitors Nitric Oxide Reagents Amino Acids & Derivatives