1-tert-Butylpiperazine
- CAS No.
- 38216-72-7
- Chemical Name:
- 1-tert-Butylpiperazine
- Synonyms
- 1-T-BUTYLPIPERAZINE;N-T-BUTYLPIPERAZINE;N-TERT-BUTYLPIPERAZINE;1-tert-Butylpiperazine;1-tert-Butylpiperazine,97%;1-(tert-Butyl)piperazine 98+%;1-(tert-Butyl)piperazine, tech;1-(1,1-Dimethylethyl)piperazine;Piperazine, 1-(1,1-dimethylethyl)-;2-Methyl-2-(piperazin-1-yl)propane
- CBNumber:
- CB3411496
- Molecular Formula:
- C8H18N2
- Molecular Weight:
- 142.24
- MDL Number:
- MFCD00049359
- MOL File:
- 38216-72-7.mol
| Product description | Number | Pack Size | Price |
| 1-tert-Butylpiperazine | B699805 | 50mg | $45 |
| 1-(tert-Butyl)piperazine 98+% | OR5147 | 1g | $21 |
| 1-(tert-Butyl)piperazine 98.0% | 3H32-1-Q4 | 1g | $23 |
| 1-tert-Butylpiperazine 95+% | 075266 | 5g | $178 |
| N-tert-Butylpiperazine | V1661 | 25g | $187 |
| More product size | |||
| Melting point | 32-35℃ |
|---|---|
| Boiling point | 85-87℃/22mm |
| Density | 0.890±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 9.27±0.10(Predicted) |
| form | Low Melting Solid |
| color | Colorless to yellow |
| Sensitive | Light, Air & Moisture Sensitive |
| InChI | InChI=1S/C8H18N2/c1-8(2,3)10-6-4-9-5-7-10/h9H,4-7H2,1-3H3 |
| InChIKey | PVMNSAIKFPWDQG-UHFFFAOYSA-N |
| SMILES | N1(C(C)(C)C)CCNCC1 |
| CAS DataBase Reference | 38216-72-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314-H318-H400 | |||||||||
| Precautionary statements | P260h-P301+P330+P331-P303+P361+P353-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN3259 | |||||||||
| HazardClass | 8 | |||||||||
| HS Code | 2933599590 | |||||||||
| Limited Quantities | 1.0 L (0.3 gallons) (liquid) or 1 Kg (2.2 lbs) (solid) | |||||||||
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml) | |||||||||
| NFPA 704 |
|
1-tert-Butylpiperazine price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B699805 | 1-tert-Butylpiperazine | 38216-72-7 | 50mg | $45 | 2021-12-16 | Buy |
| Apolloscientific | OR5147 | 1-(tert-Butyl)piperazine 98+% | 38216-72-7 | 1g | $21 | 2021-12-16 | Buy |
| SynQuest Laboratories | 3H32-1-Q4 | 1-(tert-Butyl)piperazine 98.0% | 38216-72-7 | 1g | $23 | 2021-12-16 | Buy |
| Matrix Scientific | 075266 | 1-tert-Butylpiperazine 95+% | 38216-72-7 | 5g | $178 | 2021-12-16 | Buy |
| AK Scientific | V1661 | N-tert-Butylpiperazine | 38216-72-7 | 25g | $187 | 2021-12-16 | Buy |
1-tert-Butylpiperazine Chemical Properties,Uses,Production
Synthesis Reference(s)
Tetrahedron Letters, 35, p. 7331, 1994 DOI: 10.1016/0040-4039(94)85306-1
Synthesis
507-20-0
7542-23-6
38216-72-7
General procedure for the synthesis of N-tert-butylpiperazine from chlorinated tert-butane and compound (CAS:7542-23-6): 20 mmol of compound (1) and 150 mL of tetrahydrofuran were added to a 250 mL round bottom flask. A 50 mL acetonitrile solution of 20 mmol of tert-butyl chloride was slowly added dropwise with stirring at room temperature. The dropwise addition process was completed in about 2 hours. Stirring of the reaction mixture was continued for 2 hours. It was then heated to reflux and stirred for 5 h. After completion of the reaction, the reaction was cooled to room temperature, filtered, and the solid was washed with 10 mL of tetrahydrofuran and dried to give mono-substituted piperazinic acid dihydrochloride (5) (R=tert-butyl). The compound (5) was transferred to a 250 mL round bottom flask and 200 mL of tetrahydrofuran and an appropriate amount of base was added. The reaction was heated to reflux for 4 hours under stirring. After completion of the reaction, it was cooled to room temperature, filtered, and the filtrate was evaporated by solvent to remove the low-boiling components, and the product was collected by distillation to afford the light yellow oily liquid N-tert-butylpiperazine (6) (R=tert-butyl) in 92% yield (based on the amount of tert-butyl chloride fed).
References
[1] Patent: CN106083761, 2016, A. Location in patent: Paragraph 0024; 0025
1-tert-Butylpiperazine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718; +8613336195806 | sales@capot.com | China | 29735 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10405 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8830 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from 1-tert-Butylpiperazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-02-24 | 1-tert-Butylpiperazine
38216-72-7
|
US $1.10 / g | 1g | 99.00% | 100 Tons | Dideu Industries Group Limited | |
 |
2019-09-02 | 1-tert-Butylpiperazine
38216-72-7
|
US $7.00 / KG | 1KG | 99% | JD 654 | Career Henan Chemical Co |
-
- 1-tert-Butylpiperazine
38216-72-7
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 1-tert-Butylpiperazine
38216-72-7
- US $7.00 / KG
- 99%
- Career Henan Chemical Co
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