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(+)-Bicuculline

(+)-Bicuculline
(+)-Bicuculline
CAS No.
485-49-4
Chemical Name:
(+)-Bicuculline
Synonyms
NSC 3219;NSC 32192);bicucullin;Bucuculline;BICUCULLINE;D-BICUCULLINE;(+)-BICUCULINE;(+)-BICUCULLINE;PLUS-BICUCULLINE;(+)-Bicuculline,98%
CBNumber:
CB3418662
Molecular Formula:
C20H17NO6
Formula Weight:
367.35
MOL File:
485-49-4.mol

(+)-Bicuculline Properties

Melting point:
193-197 °C
alpha 
D25 +130.5° (CHCl3)
Boiling point:
497.92°C (rough estimate)
Density 
1.3694 (rough estimate)
refractive index 
1.5600 (estimate)
storage temp. 
0-6°C
pka
4.84(at 25℃)
optical activity
[α]20/D +126±6°, c = 1% in chloroform
λmax
325nm(lit.)
Merck 
14,1203
BRN 
98786
InChIKey
IYGYMKDQCDOMRE-ZWKOTPCHSA-N
CAS DataBase Reference
485-49-4(CAS DataBase Reference)
EPA Substance Registry System
Furo[3,4-e]-1,3- benzodioxol-8(6H)-one, 6-[(5S)-5,6,7,8-tetrahydro- 6-methyl-1,3-dioxolo[4,5- g]isoquinolin-5-yl]-, (6R)-(485-49-4)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  T,N,Xn
Risk Statements  23/24/25-50-36/37/38-20/21/22
Safety Statements  36/37-45-61-36-26
RIDADR  UN 1544 6.1/PG 2
WGK Germany  3
RTECS  LV0909840
10-23
HazardClass  6.1(b)
PackingGroup  III
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H401 Toxic to aquatic life Hazardous to the aquatic environment, acute hazard Category 2 P273, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P501 Dispose of contents/container to..…

(+)-Bicuculline price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 14340 (+)-Bicuculline ≥97.0% (TLC) 485-49-4 25mg $60.2 2018-11-20 Buy
Sigma-Aldrich 14340 (+)-Bicuculline ≥97.0% (TLC) 485-49-4 100mg $93.2 2018-11-20 Buy
TCI Chemical B1890 (+)-Bicuculline >98.0%(HPLC)(T) 485-49-4 25mg $50 2018-11-22 Buy
TCI Chemical B1890 (+)-Bicuculline >98.0%(HPLC)(T) 485-49-4 100mg $150 2018-11-22 Buy
Cayman Chemical 11727 Bicuculline ≥98% 485-49-4 100mg $55 2018-11-13 Buy

(+)-Bicuculline Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid

Uses

GABAA receptor antagonist.

Uses

GABAa antagonist

Uses

Alkaloid naturally occurring in the d-form. Shows GABA antagonist activity.

Biological Activity

Classical GABA A antagonist.

Purification Methods

It crystallises from CHCl3/MeOH as plates. The crystals melt at 177o, then solidify and re-melt at 193-195o [Manske Canad J Research 21B 13 1943]. It is soluble in CHCl3, *C6H6, EtOAc but sparingly soluble in EtOH, MeOH and Et2O. [Stereochem: Blaha et al. Collect Czech Chem Commun 29 2328 1964, Snatzke et al. Tetrahedron 25 5059 1969, Pharmcol: Curtis et al. Nature 266 1222 1970, Beilstein 27 III/IV 1900].

(+)-Bicuculline Preparation Products And Raw materials

Raw materials

Preparation Products


(+)-Bicuculline Suppliers

Global( 147)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32764 55
Chengdu Biopurify Phytochemicals Ltd.
18080483897
maggie@biopurify.com CHINA 2200 58
career henan chemical co
+86-371-86658258
sales@coreychem.com CHINA 20001 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3624 58
Chembest Research Laboratories Limited +86(0)21-20908456
+86(0)21-58180499 sales@biochembest.com; market@biochembest.com China 6058 61
Chengdu Herbpurify Co.Ltd. 0086-028-85377358
0086-28-85377358 herbpurify@163.com China 1067 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15940 69
TCI (Shanghai) Development Co., Ltd. 021-67121386 / 800-988-0390
021-67121385 Sales-CN@TCIchemicals.com China 24654 81
Ascent Scientific 4401179829988
4402030 700 369 customerservice@ascentscientific.co.uk United Kingdom 282 60

View Lastest Price from (+)-Bicuculline manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2018-12-24 (+)-Bicuculline
485-49-4
US $2.00 / kg 1kg 99% 100kg career henan chemical co

(+)-Bicuculline Spectrum


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