(3,5-Di-tert-butylphenyl)boronic acid
- CAS No.
- 197223-39-5
- Chemical Name:
- (3,5-Di-tert-butylphenyl)boronic acid
- Synonyms
- (3,5-Di-tert-butylphenyl)boronic acid;5-DI-T-BUTYLPHENYLBORONIC ACID;3,5-DI-T-BUTYLPHENYLBORONIC ACID;(3,5-ditert-butylphenyl)boronicaci;3,5-Di-tert-butylbenzeneboronic acid;(3,5-Di-tert-buty|pheny|)boronic acid;3,5-Di-t-butylphenylboronic acid 95%;3,5-bis(tert-butyl)phenylboronic acid;Boronic acid, B-[3,5-bis(1,1-dimethylethyl)phenyl]-;3,5-Di-tert-butylphenylboronic Acid (contains varying amounts of Anhydride)
- CBNumber:
- CB3423655
- Molecular Formula:
- C14H23BO2
- Molecular Weight:
- 234.14
- MDL Number:
- MFCD07780212
- MOL File:
- Mol file
| Product description | Number | Pack Size | Price |
| 3,5-Di-tert-butylphenylboronic Acid (contains varying amounts of Anhydride) | D5072 | 200MG | $87 |
| 3,5-Di-tert-butylphenylboronic Acid (contains varying amounts of Anhydride) | D5072 | 500MG | $173 |
| 3,5-Di-t-butylphenylboronicacid | D429403 | 500mg | $90 |
| (3,5-Di-tert-butylphenyl)boronic acid 95+% | 091754 | 1g | $92 |
| 3,5-Di-tert-butylphenylboronicacid,97-105%(Assaybytitration) 97-105%(Assaybytitration) | 40328 | 200MG | $98.56 |
| More product size | |||
| Melting point | 182℃ (water ) |
|---|---|
| Boiling point | 333.1±52.0 °C(Predicted) |
| Density | 0.98±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | powder to crystal |
| pka | 8.74±0.10(Predicted) |
| color | White to Light yellow |
| InChI | InChI=1S/C14H23BO2/c1-13(2,3)10-7-11(14(4,5)6)9-12(8-10)15(16)17/h7-9,16-17H,1-6H3 |
| InChIKey | RPCBIEHUQSGPNA-UHFFFAOYSA-N |
| SMILES | B(C1=CC(C(C)(C)C)=CC(C(C)(C)C)=C1)(O)O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338-P362+P364 | |||||||||
| HS Code | 2931900090 | |||||||||
| NFPA 704 |
|
(3,5-Di-tert-butylphenyl)boronic acid price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5072 | 3,5-Di-tert-butylphenylboronic Acid (contains varying amounts of Anhydride) | 197223-39-5 | 200MG | $87 | 2025-07-31 | Buy |
| TCI Chemical | D5072 | 3,5-Di-tert-butylphenylboronic Acid (contains varying amounts of Anhydride) | 197223-39-5 | 500MG | $173 | 2025-07-31 | Buy |
| TRC | D429403 | 3,5-Di-t-butylphenylboronicacid | 197223-39-5 | 500mg | $90 | 2021-12-16 | Buy |
| Matrix Scientific | 091754 | (3,5-Di-tert-butylphenyl)boronic acid 95+% | 197223-39-5 | 1g | $92 | 2021-12-16 | Buy |
| Chem-Impex | 40328 | 3,5-Di-tert-butylphenylboronicacid,97-105%(Assaybytitration) 97-105%(Assaybytitration) | 197223-39-5 | 200MG | $98.56 | 2021-12-16 | Buy |
(3,5-Di-tert-butylphenyl)boronic acid Chemical Properties,Uses,Production
Description
3,5-Di-tert-butylphenylboronic acid is a colorless solid that emits light when heated. It has been used as a fluorescent probe for boronate esters, and can be synthesized by reacting 3,5-di-tert-butylphenol with boric acid. This material has also been used to prepare nanoparticles of various sizes for use in the study of emission. The emission spectrum of 3,5-Di-tert-butylphenylboronic acid is reversible and its temperature range is from -20 to 100 degrees Celsius.
Synthesis
121-43-7
22385-77-9
197223-39-5
The general procedure for the synthesis of (3,5-di-tert-butylphenyl)boronic acid from trimethyl borate and 3,5-di-tert-butylbromobenzene was as follows: 1-bromo-3,5-di-tert-butylbenzene (1-bromo-3,5-di-tert-butylbenzene) and 40 mL of tetrahydrofuran (THF) were added to a 100 mL glass reactor in a dry ice-heptane bath and Cooled to -70 °C. 16.4 mL (40.9 mmol) of n-butyllithium-hexane solution (2.5 mol/L) was slowly added dropwise and stirred for 30 min at this temperature. Subsequently, 4.25 g (40.9 mmol) of trimethyl borate was added at -78 °C and stirring was continued for 2 hours. The reaction mixture was then warmed to room temperature and stirred for 12 hours. Upon completion of the reaction, 1 M aqueous hydrochloric acid was slowly added to the reaction solution and the pH was adjusted to 3. The reaction solution was transferred to a separatory funnel and extracted three times with tert-butyl methyl ether (MTBE). The organic phases were combined and dried over anhydrous sodium sulfate. The desiccant was removed by filtration and the organic phase was concentrated under reduced pressure to give the crude product. Finally, the crude product was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=20/1) to afford 8.00 g (91% yield) of 3,5-di-tert-butylphenylboronic acid (3,5-di-tert-butylphenylboronic acid) as a pale yellow solid.
References
[1] Patent: JP5710035, 2015, B2. Location in patent: Paragraph 0169
[2] Chemical Communications, 2015, vol. 51, # 10, p. 1926 - 1929
[3] Chemistry - A European Journal, 2012, vol. 18, # 14, p. 4174 - 4178
[4] Patent: EP2532687, 2012, A2
(3,5-Di-tert-butylphenyl)boronic acid Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20171 | 58 |
| Hubei Lidu New Material Technology Co., Ltd | +86-19307248857 +86-19307248857 | 19307248857@163.com | China | 866 | 58 |
| Springchem New Material Technology Co.,Limited | +86-021-62885108 +8613917661608 | info@spring-chem.com | China | 2068 | 57 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13505 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Zhengzhou HQ Material CO.,LTD. | +86-371-55919009 +8615225108189 | sale1@hqmat.com | China | 1001 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
View Lastest Price from (3,5-Di-tert-butylphenyl)boronic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-11-12 | 3,5-Di-tert-butylbenzeneboronic acid
197223-39-5
|
US $0.00-0.00 / kg | 1kg | 98% | 20 tons | Hubei Lidu New Material Technology Co., Ltd | |
 |
2025-09-25 | 3,5-DI-T-BUTYLPHENYLBORONIC ACID
197223-39-5
|
US $50.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2019-07-06 | 3,5-DI-T-BUTYLPHENYLBORONIC ACID
197223-39-5
|
US $1.00 / KG | 1KG | 99% | Customized | Career Henan Chemical Co |
-
- 3,5-Di-tert-butylbenzeneboronic acid
197223-39-5
- US $0.00-0.00 / kg
- 98%
- Hubei Lidu New Material Technology Co., Ltd
-
- 3,5-DI-T-BUTYLPHENYLBORONIC ACID
197223-39-5
- US $50.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3,5-DI-T-BUTYLPHENYLBORONIC ACID
197223-39-5
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
