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Lupeol

Description References
Lupeol
Lupeol
CAS No.
545-47-1
Chemical Name:
Lupeol
Synonyms
LUPEOL;Lupenol;Clerodol;B-VISCOL;MONOGYNOL;LUPEOL(P);NSC 90487;monogynolb;Cautchicol;Fagarsterol
CBNumber:
CB3429132
Molecular Formula:
C30H50O
Formula Weight:
426.72
MOL File:
545-47-1.mol

Lupeol Properties

Melting point:
215°
alpha 
D20 +27.2° (c = 4.8 in chloroform)
Boiling point:
482.1°C (rough estimate)
Density 
0.9457
refractive index 
1.4910 (estimate)
storage temp. 
2-8°C
InChIKey
MQYXUWHLBZFQQO-QGTGJCAVSA-N
CAS DataBase Reference
545-47-1(CAS DataBase Reference)
NIST Chemistry Reference
Lupeol(545-47-1)

SAFETY

Safety Statements  24/25
WGK Germany  2
RTECS  OK5763000

Lupeol price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich L5632 Lupeol ≥94% 545-47-1 25mg $94.9 2018-11-13 Buy
Sigma-Aldrich 18692 Lupeol analytical standard 545-47-1 10mg $130 2018-11-13 Buy
Cayman Chemical 11215 Lupeol ≥98% 545-47-1 5mg $15 2018-11-13 Buy
Cayman Chemical 11215 Lupeol ≥98% 545-47-1 10mg $29 2018-11-13 Buy
Sigma-Aldrich L5632 Lupeol ≥94% 545-47-1 100mg $284 2018-11-13 Buy

Lupeol Chemical Properties,Uses,Production

Description

Lupeol is a kind of novel anti-inflammatory and anti-cancer dietary triterpene that can be found in white cabbage, green pepper, strawberry, olive, mangoes and grapes. In recent years, much progress has been made on the application of this molecule for clinical treatment of various kind of disorders. On the one hand, it has been extensively studied that it is capable of inhibiting inflammation under both in vitro and in animal models. Studies have shown that Lupeol is a multi-target agent during its anti-inflammation effect, targeting on many key molecular pathways involving nuclear factor kappa B (NFκB), cFLIP, Fas, Kras, phosphatidylinositol-3-kinase (PI3K)/Akt and Wnt/β-catenin. On the other hand, Lupeol has strong anti-tumor effect during treatment of various cancer types such as prostate, skin, pancreatic and breast cancer. The anti-tumor effect might be related to its potential to modulate important signaling pathways such as nuclear factor kappa B (NFκB) and the phosphatidylinositol 3-kinase [PI3K] /Akt (protein kinase B pathway), which are crucial during tumorigenesis.

References

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764818/
https://en.wikipedia.org/wiki/Lupeol

Chemical Properties

White powder

Uses

antineoplastic

Uses

Abundant plant triterpene. Occurs in the skin of lupin seeds, in circle, in the latex of fig trees and of rubber plants. It was detected in cocoons of Bombyx mori.

Definition

ChEBI: A pentacyclic triterpenoid that is lupane in which the hydrogen at the 3beta position is substituted by a hydroxy group. It occurs in the skin of lupin seeds, as well as in the latex of fig trees and of rubber plants. It is also found in m ny edible fruits and vegetables.

Lupeol Preparation Products And Raw materials

Raw materials

Preparation Products


Lupeol Suppliers

Global( 125)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32764 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3625 58
Nanjing Spring & Autumn Biological Engineering Co., Ltd. 025-84430028 13815430202 QQ:1372713209
sale02@cqherb.com China 269 59
Shanghai Boyle Chemical Co., Ltd. 86-15221043597
86-21-57758967 sales@boylechem.com China 2898 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40399 62
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15940 69
Chembest Research Laboratories Limited +86(0)21-20908456
+86(0)21-58180499 sales@biochembest.com; market@biochembest.com China 6070 61
BeiJing Hwrk Chemicals Limted 4006990298;010-57411839;0757-86311057;021-51691807
010-87653215;0757-86311057;021-55236763 sales@hwrkchemical.com China 14687 55
Energy Chemical 021-58432009 / 400-005-6266
021-58436166-800 info@energy-chemical.com China 44192 61

545-47-1(Lupeol)Related Search:


  • MONOGYNOL
  • Complex Molecules
  • (3-beta)-lup-20(29)-en-3-o
  • (3-beta)-lup-20(29)-en-3-ol
  • 1H-Cyclopenta[a]chrysene, lup-20(29)-en-3-ol deriv.
  • Clerodol
  • Fagarsterol
  • lup-20(29)-en-3-beta-ol
  • Lup-20(29)-en-3beta-ol
  • Lup-20(29)-en-3-ol
  • Lup-20(29)-en-3-ol, (3beta)-
  • Lupenol
  • Monogynol B
  • monogynolb
  • Triterpene lupeol
  • LUPEOL
  • FAGARASTEROL
  • BETA-VISCOL
  • B-VISCOL
  • 3B-HYDROXY-20[29]-LUPENE
  • 3BETA-HYDROXY-20[29]-LUPENE
  • 545-47-1
  • 20[29]-LUPEN-3BETA-OL
  • Asymmetric Synthesis
  • Chiral Building Blocks
  • 20(29)-lupen-3β-ol
  • LUPEOL(P)
  • LUPEOL(UNSPECIFIEDISOMER)
  • LUPEOL hplc
  • Tri-Terpenoids
  • LUPEOL WITH HPLC
  • Lup-20(29)-en-3-ol,(3β)-
  • 3β-Hydroxy-20(29)-lu
  • 3β-Hydroxy-20(29)-lupene
  • Lupeol(Fagarasterol)
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
  • (3β)-Lup-20(29)-en-3-ol
  • 3β-Hydroxylup-20(29)-ene
  • NSC 90487
  • Cautchicol
  • Xanthosterin
  • Lup-20(29)-en-3b-ol
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Lupeol, froM Crataegus pinnatifida
  • Lup-20(29)-en-3-ol, (3b)-
  • Lupeol >=94%
  • Lupeol (3beta)-Lup-20(29)-en-3-ol
  • Inhibitors
  • Lupeol, 98%, from Crataegus pinnatifida Bunge
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