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6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE

CAS No.
89466-18-2
Chemical Name:
6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE
Synonyms
6-BROMO-2-METHOXYPYRIDIN-3-AMINE;EOS-60782;Pyridine,3-amino-6-bromo-2-met;3-Amino-6-bromo-2-methoxypyridine;6-Bromo-2-methoxy-3-aminopyridine;3-Amino-2-Methoxy-6-Bromopyridine;3-Pyridinamine, 6-bromo-2-methoxy-;6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE;2-Bromo-6-methoxy-pyridin-3-ylamine;5,6-dibromo-2-methoxypyridin-3-amine
CBNumber:
CB3431801
Molecular Formula:
C6H7BrN2O
Molecular Weight:
203.04
MDL Number:
MFCD06738312
MOL File:
89466-18-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:28
Product description Number Pack Size Price
3-Amino-6-bromo-2-methoxypyridine A594540 500mg $95
3-Amino-6-bromo-2-methoxypyridine FA38696 2g $95
3-Amino-6-bromo-2-methoxypyridine Y14769 5g $100
3-Amino-6-bromo-2-methoxypyridine FA38696 5G $220
3-Amino-6-bromo-2-methoxypyridine Y14769 1g $25
More product size

6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE Properties

Melting point 78-79 °C (sublm)
Boiling point 277.6±35.0 °C(Predicted)
Density 1.622±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 1.81±0.10(Predicted)
Appearance Light brown to brown Solid
InChI InChI=1S/C6H7BrN2O/c1-10-6-4(8)2-3-5(7)9-6/h2-3H,8H2,1H3
InChIKey HSVYYOLSYNEVSP-UHFFFAOYSA-N
SMILES C1(OC)=NC(Br)=CC=C1N
CAS DataBase Reference 89466-18-2

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H302+H312+H332-H314
Precautionary statements  P501-P260-P270-P271-P264-P280-P362+P364-P303+P361+P353-P301+P330+P331-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P405
Risk Statements  20/21/22-37/38-48
Safety Statements  22-26-7/8-36/37/39-45
HS Code  29333990

6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A594540 3-Amino-6-bromo-2-methoxypyridine 89466-18-2 500mg $95 2021-12-16 Buy
Biosynth Carbosynth FA38696 3-Amino-6-bromo-2-methoxypyridine 89466-18-2 2g $95 2021-12-16 Buy
Frontier Specialty Chemicals Y14769 3-Amino-6-bromo-2-methoxypyridine 89466-18-2 5g $100 2021-12-16 Buy
Biosynth Carbosynth FA38696 3-Amino-6-bromo-2-methoxypyridine 89466-18-2 5G $220 2021-12-16 Buy
Frontier Specialty Chemicals Y14769 3-Amino-6-bromo-2-methoxypyridine 89466-18-2 1g $25 2021-12-16 Buy
Product number Packaging Price Buy
A594540 500mg $95 Buy
FA38696 2g $95 Buy
Y14769 5g $100 Buy
FA38696 5G $220 Buy
Y14769 1g $25 Buy

6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE Chemical Properties,Uses,Production

Uses

3-Amino-2-methoxy-6-bromopyridine is an organic heterocyclic compound that can be used as a pharmaceutical intermediate.

Chemical Properties

Brown powder

Synthesis

2-Methoxypyridin-3-amine

20265-38-7

6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE

89466-18-2

2-Methoxypyridin-3-amine (39.4 g) was dissolved in N,N-dimethylformamide (200 mL) and the solution was cooled to -30 °C. A solution of N,N-dimethylformamide (100 mL) of N-bromosuccinimide (62.1 g) was slowly added dropwise with stirring. After the dropwise addition, the reaction was continued with stirring for 30 minutes. Subsequently, the reaction mixture was poured into water and extracted with chloroform. The organic layers were combined and washed sequentially with saturated sodium sulfite solution, water and brine. The organic layer was dried with anhydrous sodium sulfate, filtered and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent ratio: hexane:ethyl acetate=9:1→4:1) to afford 6-bromo-2-methoxypyridin-3-amine as a yellow powder (51.9 g, 80% yield). The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3) and mass spectrometry: 1H NMR δppm 3.64-3.84 (m, 2H), 3.98 (s, 3H), 6.78 (dd, J=7.9,1.0 Hz, 1H), 6.87 (d, J=7.9 Hz, 1H); MS (+): 203 [M+H]+.

References

[1] Patent: US2011/237791, 2011, A1. Location in patent: Page/Page column 64
[2] Patent: WO2018/30550, 2018, A1. Location in patent: Paragraph 0648

58819-77-5
89466-18-2
Synthesis of 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE from 6-BROMO-2-METHOXY-3-NITRO-PYRIDINE
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View Lastest Price from 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Bromo-2-methoxy-3-pyridinamine pictures 2026-04-17 5-Bromo-2-methoxy-3-pyridinamine
89466-18-2
US $2.00-6.00 / KG 1KG 99% g-kg-tons ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
3-Amino-6-broMo-2-Methoxypyridine pictures 2020-05-13 3-Amino-6-broMo-2-Methoxypyridine
89466-18-2
US $0.00-0.00 / Kg 1KG 99.0% 500 MT Shaanxi Dideu Medichem Co. Ltd
3-AMino-6-broMo-2-Methoxypyridine  pictures 2019-12-26 3-AMino-6-broMo-2-Methoxypyridine
89466-18-2
US $1.00 / KG 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd

6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE Spectrum

6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE 6-Bromo-2-methoxy-3-aminopyridine 3-Amino-6-bromo-2-methoxypyridine 6-Bromo-2-methoxy-pyridin-3-ylamine ,97% 6-bromo-2-methoxy –pyridine -3-ylamine 2-Bromo-6-methoxy-pyridin-3-ylamine 3-PYRIDINE AMINE-6-BROMO-2-METHOXY (LR) EOS-60782 3-Pyridinamine, 6-bromo-2-methoxy- 89466-18-2 3-AMino-6-broMo-2-Methoxypyridine 5,6-dibromo-2-methoxypyridin-3-amine 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE ISO 9001:2015 REACH 3-Amino-2-Methoxy-6-Bromopyridine 6-BROMO-2-METHOXYPYRIDIN-3-AMINE Pyridine,3-amino-6-bromo-2-met 89466-18-2 189466-18-2