6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE
- CAS No.
- 89466-18-2
- Chemical Name:
- 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE
- Synonyms
- 6-BROMO-2-METHOXYPYRIDIN-3-AMINE;EOS-60782;Pyridine,3-amino-6-bromo-2-met;3-Amino-6-bromo-2-methoxypyridine;6-Bromo-2-methoxy-3-aminopyridine;3-Amino-2-Methoxy-6-Bromopyridine;3-Pyridinamine, 6-bromo-2-methoxy-;6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE;2-Bromo-6-methoxy-pyridin-3-ylamine;5,6-dibromo-2-methoxypyridin-3-amine
- CBNumber:
- CB3431801
- Molecular Formula:
- C6H7BrN2O
- Molecular Weight:
- 203.04
- MDL Number:
- MFCD06738312
- MOL File:
- 89466-18-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3-Amino-6-bromo-2-methoxypyridine | A594540 | 500mg | $95 |
| 3-Amino-6-bromo-2-methoxypyridine | FA38696 | 2g | $95 |
| 3-Amino-6-bromo-2-methoxypyridine | Y14769 | 5g | $100 |
| 3-Amino-6-bromo-2-methoxypyridine | FA38696 | 5G | $220 |
| 3-Amino-6-bromo-2-methoxypyridine | Y14769 | 1g | $25 |
| More product size | |||
| Melting point | 78-79 °C (sublm) |
|---|---|
| Boiling point | 277.6±35.0 °C(Predicted) |
| Density | 1.622±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 1.81±0.10(Predicted) |
| Appearance | Light brown to brown Solid |
| InChI | InChI=1S/C6H7BrN2O/c1-10-6-4(8)2-3-5(7)9-6/h2-3H,8H2,1H3 |
| InChIKey | HSVYYOLSYNEVSP-UHFFFAOYSA-N |
| SMILES | C1(OC)=NC(Br)=CC=C1N |
| CAS DataBase Reference | 89466-18-2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302+H312+H332-H314 |
| Precautionary statements | P501-P260-P270-P271-P264-P280-P362+P364-P303+P361+P353-P301+P330+P331-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P405 |
| Risk Statements | 20/21/22-37/38-48 |
| Safety Statements | 22-26-7/8-36/37/39-45 |
| HS Code | 29333990 |
6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A594540 | 3-Amino-6-bromo-2-methoxypyridine | 89466-18-2 | 500mg | $95 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA38696 | 3-Amino-6-bromo-2-methoxypyridine | 89466-18-2 | 2g | $95 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | Y14769 | 3-Amino-6-bromo-2-methoxypyridine | 89466-18-2 | 5g | $100 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA38696 | 3-Amino-6-bromo-2-methoxypyridine | 89466-18-2 | 5G | $220 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | Y14769 | 3-Amino-6-bromo-2-methoxypyridine | 89466-18-2 | 1g | $25 | 2021-12-16 | Buy |
6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE Chemical Properties,Uses,Production
Uses
3-Amino-2-methoxy-6-bromopyridine is an organic heterocyclic compound that can be used as a pharmaceutical intermediate.
Chemical Properties
Brown powder
Synthesis
20265-38-7
89466-18-2
2-Methoxypyridin-3-amine (39.4 g) was dissolved in N,N-dimethylformamide (200 mL) and the solution was cooled to -30 °C. A solution of N,N-dimethylformamide (100 mL) of N-bromosuccinimide (62.1 g) was slowly added dropwise with stirring. After the dropwise addition, the reaction was continued with stirring for 30 minutes. Subsequently, the reaction mixture was poured into water and extracted with chloroform. The organic layers were combined and washed sequentially with saturated sodium sulfite solution, water and brine. The organic layer was dried with anhydrous sodium sulfate, filtered and the filtrate was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent ratio: hexane:ethyl acetate=9:1→4:1) to afford 6-bromo-2-methoxypyridin-3-amine as a yellow powder (51.9 g, 80% yield). The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3) and mass spectrometry: 1H NMR δppm 3.64-3.84 (m, 2H), 3.98 (s, 3H), 6.78 (dd, J=7.9,1.0 Hz, 1H), 6.87 (d, J=7.9 Hz, 1H); MS (+): 203 [M+H]+.
References
[1] Patent: US2011/237791, 2011, A1. Location in patent: Page/Page column 64
[2] Patent: WO2018/30550, 2018, A1. Location in patent: Paragraph 0648
6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE Preparation Products And Raw materials
Raw materials
1of4
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Honest Joy Holdings Limited | 0755-36694831 +8613717124449 | sale@feiyang.com.cn | China | 300 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16513 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 4000 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30227 | 58 |
| NINGBOBENKANGJS PHARMTECHCO., LTD | +8615990591583 15990591583 | CHINA | 2029 | 58 |
View Lastest Price from 6-BROMO-2-METHOXY-PYRIDIN-3-YLAMINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-17 | 5-Bromo-2-methoxy-3-pyridinamine
89466-18-2
|
US $2.00-6.00 / KG | 1KG | 99% | g-kg-tons | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | |
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2020-05-13 | 3-Amino-6-broMo-2-Methoxypyridine
89466-18-2
|
US $0.00-0.00 / Kg | 1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd | |
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2019-12-26 | 3-AMino-6-broMo-2-Methoxypyridine
89466-18-2
|
US $1.00 / KG | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd |
-

- 5-Bromo-2-methoxy-3-pyridinamine
89466-18-2
- US $2.00-6.00 / KG
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-

- 3-Amino-6-broMo-2-Methoxypyridine
89466-18-2
- US $0.00-0.00 / Kg
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-

- 3-AMino-6-broMo-2-Methoxypyridine
89466-18-2
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd







