2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
- CAS No.
- 34486-06-1
- Chemical Name:
- 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
- Synonyms
- Picoxystrobin M3;2-Hydroxy-6-(trifL;2-Hydroxy-6-trifluoromethyl;2(1H)-Pyridinone, 6-(trifluor;6-TRIFLUOROMETHYLPYRIDIN-2-ONE;6-(Trifluoromethyl)pyrid-2-one;6-TRIFLUOROMETHYL-PYRIDINE-2-OL;6-(Trifluoromethyl)pyridin-ylol;6-trifluoromethyl-1H-pyridin-2-one;2-HYDROXY-6-TRIFLUOROMETHYLPRIDINE
- CBNumber:
- CB3433719
- Molecular Formula:
- C6H4F3NO
- Molecular Weight:
- 163.1
- MDL Number:
- MFCD08061317
- MOL File:
- 34486-06-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Hydroxy-6-trifluoromethylpyridine | H977575 | 250mg | $55 |
| 2-Hydroxy-6-(trifluoromethyl)pyridine 98% | 024690 | 5g | $55 |
| 2-Hydroxy-6-(trifluoromethyl)pyridine | PC9263 | 1g | $12 |
| 2-Hydroxy-6-trifluoromethylpyridine | J97316 | 1g | $15 |
| 2-Hydroxy-6-(trifluoromethyl)pyridine 98% | 024690 | 1g | $18 |
| More product size | |||
| Melting point | 124-126° |
|---|---|
| Boiling point | 223.7±40.0 °C(Predicted) |
| Density | 1.398±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 8.03±0.10(Predicted) |
| color | White to Off-White |
| InChI | InChI=1S/C6H4F3NO/c7-6(8,9)4-2-1-3-5(11)10-4/h1-3H,(H,10,11) |
| InChIKey | XXRUAAOADAPPII-UHFFFAOYSA-N |
| SMILES | C1(=O)NC(C(F)(F)F)=CC=C1 |
| CAS DataBase Reference | 34486-06-1(CAS DataBase Reference) |
| FDA UNII | 81T56GP86W |
| EPA Substance Registry System | 2(1H)-Pyridinone, 6-(trifluoromethyl)- (34486-06-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H341 |
| Precautionary statements | P501-P202-P201-P264-P280-P302+P352-P308+P313-P337+P313-P305+P351+P338-P362+P364-P332+P313-P405 |
| Hazard Codes | T,Xi |
| Risk Statements | 36/37/38-36-25 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | 2811 |
| HazardClass | IRRITANT |
| PackingGroup | Ⅲ |
| HS Code | 2933399990 |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE price More Price(27)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | H977575 | 2-Hydroxy-6-trifluoromethylpyridine | 34486-06-1 | 250mg | $55 | 2021-12-16 | Buy |
| Matrix Scientific | 024690 | 2-Hydroxy-6-(trifluoromethyl)pyridine 98% | 34486-06-1 | 5g | $55 | 2021-12-16 | Buy |
| Apolloscientific | PC9263 | 2-Hydroxy-6-(trifluoromethyl)pyridine | 34486-06-1 | 1g | $12 | 2021-12-16 | Buy |
| AK Scientific | J97316 | 2-Hydroxy-6-trifluoromethylpyridine | 34486-06-1 | 1g | $15 | 2021-12-16 | Buy |
| Matrix Scientific | 024690 | 2-Hydroxy-6-(trifluoromethyl)pyridine 98% | 34486-06-1 | 1g | $18 | 2021-12-16 | Buy |
2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE Chemical Properties,Uses,Production
Uses
2-Hydroxy-6-trifluoromethylpyridine
Synthesis
39890-95-4
34486-06-1
(3) 1500 g of tert-butanol, 140 g of potassium hydroxide and 2-chloro-6-trifluoromethylpyridine prepared in step (2) were added to a 3 L reaction flask, heated up to 70 °C, and the reaction was held for 8 hours. After completion of the reaction, tert-butanol was removed by distillation under reduced pressure, 550 g of ethyl acetate and 550 g of water were added and mixed with stirring. The organic layer was washed with 370 g of saturated brine and dried by adding 100 g of anhydrous sodium sulfate. The ethyl acetate was removed by rotary evaporation to obtain 172.4 g of crude product; (4) The crude product prepared in step (3) was dissolved in 150 g of ethyl acetate, heated to 70 °C and stirred. 1200 g of petroleum ether was added slowly dropwise and the mixture was cooled to 2°C after the dropwise addition was completed, solid crystals were precipitated and the solid was collected by filtration. The solid was washed with 50 g of petroleum ether and dried at 70 °C to give 131.2 g of 2-hydroxy-6-trifluoromethylpyridine as a light yellow solid powder in 80.8% yield.
References
[1] Patent: CN106866512, 2017, A. Location in patent: Paragraph 0014
[2] Patent: US5973159, 1999, A
[3] Patent: CN107759513, 2018, A. Location in patent: Paragraph 0017
2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Jihui Chemical Co., Ltd. | +8615053042019 | sales@jihuichem.com | China | 34 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Anhui Yiao New Material Technology Co., Ltd | +86-18033737140 +86-17354101231 | sales1@hbganmiao.com | China | 227 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 615 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718; +8613336195806 | sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13843 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21590 | 55 |
| AB PharmaTech,LLC | 323-480-4688 | sales@acrospharmatech.com | United States | 989 | 55 |
View Lastest Price from 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
34486-06-1
|
US $1.00 / KG | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
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2026-02-28 | 2-Hydroxy-6-trifluoromethylpyridine
34486-06-1
|
US $0.00-0.00 / KG | 1KG | Purity: 99% | 1000 | Shandong Jihui Chemical Co., Ltd. | |
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2025-12-01 | 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
34486-06-1
|
US $0.00 / kg | 1kg | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd |
-

- 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
34486-06-1
- US $1.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- 2-Hydroxy-6-trifluoromethylpyridine
34486-06-1
- US $0.00-0.00 / KG
- Purity: 99%
- Shandong Jihui Chemical Co., Ltd.
-

- 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
34486-06-1
- US $0.00 / kg
- 98%
- Shaanxi Dideu New Materials Co. Ltd
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