ChemicalBook >> CAS DataBase List >>5-Fluoro-2-oxindole
5-Fluoro-2-oxindole
- CAS No.
- 56341-41-4
- Chemical Name:
- 5-Fluoro-2-oxindole
- Synonyms
- 5-Fluoro-1,3-dihydro-indol-2-one;5-FLUORO-2-OXYINDOLE;5-FLUOROOXINDOLE;uorooxindoL;Fluorooxindole;5-FLUROOXINDOLE;5-FLUORO-2-OXINDOLE;5-Fluorooxindole98%;5-Fluorooxindole>5-Fluor0-2-oxindole
- CBNumber:
- CB3437333
- Molecular Formula:
- C8H6FNO
- Molecular Weight:
- 151.14
- MDL Number:
- MFCD02179598
- MOL File:
- 56341-41-4.mol
Last updated:2024-03-27 13:45:20
| Melting point | 143-147 °C (lit.) |
|---|---|
| Boiling point | 307.2±42.0 °C(Predicted) |
| Density | 1.311±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Powder or Crystalline Powder |
| pka | 12.99±0.20(Predicted) |
| color | White to pale brown |
| InChIKey | DDIIYGHHUMKDGI-UHFFFAOYSA-N |
| CAS DataBase Reference | 56341-41-4(CAS DataBase Reference) |
| FDA UNII | 4EW64J5JHC |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,C | |||||||||
| Risk Statements | 36/37/38-34 | |||||||||
| Safety Statements | 22-24/25-45-36/37/39-27-26 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant/Keep Cold | |||||||||
| HazardClass | IRRITANT, KEEP COLD | |||||||||
| HS Code | 29339900 | |||||||||
| NFPA 704 |
|
5-Fluoro-2-oxindole price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 586579 | 5-Fluoro-2-oxindole 97% | 56341-41-4 | 500mg | $133 | 2023-06-20 | Buy |
| TCI Chemical | F0699 | 5-Fluorooxindole >98.0%(GC) | 56341-41-4 | 1g | $65 | 2024-03-01 | Buy |
| TCI Chemical | F0699 | 5-Fluorooxindole >98.0%(GC) | 56341-41-4 | 5g | $208 | 2024-03-01 | Buy |
| Alfa Aesar | H32176 | 5-Fluorooxindole, 97% | 56341-41-4 | 1g | $82.65 | 2024-03-01 | Buy |
| TRC | F595140 | 5-Fluoro-2-oxindole | 56341-41-4 | 25g | $990 | 2021-12-16 | Buy |
5-Fluoro-2-oxindole Chemical Properties,Uses,Production
Chemical Properties
Light Yellow Crystalline
Uses
5-Fluoro-2-oxindole (cas# 56341-41-4) is a compound useful in organic synthesis.
Application
5-Fluoro-2-oxindole is a ketone organic compound that can be used as an intermediate in the preparation of sunitinib. Sunitinib is a novel multi-targeted oral drug for the treatment of tumors.
Preparation
synthesis of 5-fluoro-2-oxindole: 4-fluoroaniline was used as the starting material, reacted with chloral hydrate and hydroxylamine hydrochloride to generate 4-fluoroisonitrosoacetanilide, and then cyclized under the action of concentrated sulfuric acid to form the compound 5-fluoroisatin was finally obtained by wolff-kishner-huang minlon reduction to obtain 5-fluoro-2-oxindole with a total yield of 66%.
5-Fluoro-2-oxindole Preparation Products And Raw materials
Raw materials
Lithium chloride
1-hydroxy-3H-indol-2-one
Ethyl iodoacetate
4-FLUOROISONITROSOACETANILIDE
5-Fluoro-3-hydrazonoindolin-2-one
1of4
Preparation Products
Global( 607)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Allfluoro pharmaceutical co. ltd. | 021-26137118 +8615821363818 | sales@allfluoro.com | China | 5791 | 58 |
| Senova Technology Co. Ltd. | +86-0755-86703119 +8618503098836 | info@senovatech.com | China | 350 | 58 |
| Shanghai QiXin New Materials Technology Co.,Ltd | +8615116235351 | derrickguo@sh-qixin.cn | China | 16 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 | sales@zjgoldpharm.com | China | 5905 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | qinhe02@xaltbio.com | China | 1000 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 7933 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 811 | 58 |
Related articles
- Pharmaceutical Intermediate - 5-Fluoro-2-oxindole
- 5- fluorindole-2 - ketone is a useful intermediate of sunitinib and its derivatives. Sunitinib is the first of a new class of ....
- Feb 22，2022
View Lastest Price from 5-Fluoro-2-oxindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-12 | 5-Fluorooxindole
56341-41-4
|
US $0.00 / kg | 1kg | 99% | 2000ton | Shaanxi Haibo Biotechnology Co., Ltd | |
 |
2024-03-27 | 5-Fluoro-2-oxindole
56341-41-4
|
US $5.00-0.10 / KG | 1KG | 98% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-12-20 | 5-Fluoro-2-oxindole
56341-41-4
|
US $0.00-0.00 / kg | 1kg | 98% | 1 ton | Nanjing Fred Technology Co., Ltd |
-
- 5-Fluorooxindole
56341-41-4
- US $0.00 / kg
- 99%
- Shaanxi Haibo Biotechnology Co., Ltd
-
- 5-Fluoro-2-oxindole
56341-41-4
- US $5.00-0.10 / KG
- 98%
- Henan Fengda Chemical Co., Ltd
-
- 5-Fluoro-2-oxindole
56341-41-4
- US $0.00-0.00 / kg
- 98%
- Nanjing Fred Technology Co., Ltd
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