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5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole structure

CAS No.: 124750-53-4

Chemical Name:: 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole

Synonyms: TTMB;ENTERPRISESTANDARD;Losartan Impurity 9;Olmesartan TTMB impurity;5-[2-(4-methylphenyl)phenyl]-1-trityltetrazole;5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole;5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole;Olmesartan Medoxomil Impurity 24（Losartan Impurity 9）;N-(TRIPHENYLMETHYL)-5-(4'-METHYLBIPHENYL-2-YL)TETRAZOLE;n-(triphenylmethyl)-5-(4'-methylbiphenyl-2-yl-)terazole

CBNumber:: CB3438158

Molecular Formula:: C33H26N4

Molecular Weight:: 478.59

MDL Number:: MFCD00665220

MOL File:: 124750-53-4.mol

MSDS File:: SDS

Last updated:2023-04-23 13:52:06

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5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Properties

Melting point	166-169 °C(Solv: ethyl acetate (141-78-6); dichloromethane (75-09-2))
Boiling point	681.6±65.0 °C(Predicted)
Density	1.13±0.1 g/cm3(Predicted)
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly)
form	Solid
pka	0.30±0.10(Predicted)
color	Off-White
CAS DataBase Reference	124750-53-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Danger
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	T889172	N-Triphenylmethyl-5-[4''-methylbiphenyl-2-yl]tetrazole-d4	124750-53-4	10mg	$165	2021-12-16	Buy
Matrix Scientific	093682	5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 95+%	124750-53-4	250mg	$341	2021-12-16	Buy
Medical Isotopes, Inc.	D62492	N-Triphenylmethyl-5-[4??-methylbiphenyl-2-yl]tetrazole-d4	124750-53-4	10mg	$650	2021-12-16	Buy
Matrix Scientific	093682	5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 95+%	124750-53-4	1g	$756	2021-12-16	Buy
American Custom Chemicals Corporation	APN0000403	5-(4'-METHYLBIPHENYL-2-YL)-1-TRITYL-1H-TETRAZOLE 95.00%	124750-53-4	1G	$780.15	2021-12-16	Buy

Product number	Packaging	Price	Buy
T889172	10mg	$165	Buy
093682	250mg	$341	Buy
D62492	10mg	$650	Buy
093682	1g	$756	Buy
APN0000403	1G	$780.15	Buy

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Chemical Properties,Uses,Production

Chemical Properties

Off-white Solid

Uses

An intermediate in the preparation of labelled Candesartan.

Uses

5-?(4''-?Methyl-?[1,?1''-?biphenyl]?-?2-?yl)?-?1-?trityl-?1H-?tetrazole is a reactant in the synthesis of anti-microbial agents.

Synthesis

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole is prepared by the reaction of trityl chloride and 2-(tetrazol-5-yl)-4'-methyl-1,1'-biphenyl. The specific synthesis steps are as follows:
Dissolve compound 2 (200 g) with stirring at 40°C 700mL of acetone, Aqueous sodium hydroxide solution (40.67 g sodium hydroxide dissolved in 160 mL water) is added, Continue stirring for 1h, A solution of triphenylchloromethane in acetone (270.8 g of triphenylmethyl chloride dissolved in 800 mL of acetone) was initially added dropwise. The solid was added dropwise and gradually evolved into a white turbid liquid. The reaction was monitored by TLC until it was completely filtered off and washed with water to give a solid as intermediate 3. The solid was blow dried at 50°C to give white intermediate 3 (385 g), yield: 95.2%, HPLC: 99.44%.
5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole synthesis

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Preparation Products And Raw materials

Raw materials

Preparation Products

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole Suppliers

Global( 172)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5909	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12468	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Xiamen AmoyChem Co., Ltd	58
Shandong chuangyingchemical Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Zhengzhou Alfa Chemical Co.,Ltd	58
SIMAGCHEM CORP	58

View Lastest Price from 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2022-09-21	5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 124750-53-4	US $0.00-0.00 / kg	1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2021-08-11	5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole USP/EP/BP 124750-53-4	US $1.10 / g	1g	99.9%	100 Tons min	Dideu Industries Group Limited
2020-05-10	5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 124750-53-4	US $0.00-0.00 / Kg	1KG	99.0%	500 MT	Shaanxi Dideu Medichem Co. Ltd

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
124750-53-4
US $0.00-0.00 / kg
98%
Henan Aochuang Chemical Co.,Ltd.

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole USP/EP/BP
124750-53-4
US $1.10 / g
99.9%
Dideu Industries Group Limited

5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole
124750-53-4
US $0.00-0.00 / Kg
99.0%
Shaanxi Dideu Medichem Co. Ltd

124750-53-4(5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole)Related Search:

Triphenylmethyl Chloride Trityl candesartan Trityl Irbesartan Trityl candesartan cilexetil 4,4'-Dimethylbiphenyl

2,3,5-Triphenyltetrazolium chloride Silicone oil (high temperature) Chlorodimethylphenylsilane Trityl olmesartan 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

2-Butyl-4-chloro-5-hydroxymethyl-1-[[2'-(1H-2-triphenylmethyl-tetrazol-5-yl)biphenyl-4-yl]methyl]imidazole 4-Phenyltoluene methylphenyl silicone resin Benzyl N-[(2(Trityltetrazol-5-yl-1,1biphenyl-4-yl]-methyl-2-amino-3-methylbutanoate 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole

AKOS 91708 AKOS 91707

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5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 5-[4'-METHYL (1,1'-BIPHENYL)-2-YL]-1-TRIPHENYLMETHYL-TETRAZOLE n-(triphenylmethyl)-5-(4'-methylbiphenyl-2-yl-)terazole N-(TRIPHENYLMETHYL)-5-(4'-METHYLBIPHENYL-2-YL)TETRAZOLE 5-(4'-Methyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 5-[4''-METHYL (1,1''-BIPHENYL)-2-YL]-1-TRIPHENYLMETHYL-TETRAZOLE 98.5+% N-TriphenylMethyl-5-[4'-Methylbiphenyl-2-yl]tetrazole-d4 5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole ENTERPRISESTANDARD 5-(5-Methyl-2-phenylphenyl)-1-(triphenylMethyl)-1H-1,2,3,4-tetrazole Losartan IMpurity (5-(4'-Methylbiphenyl-2-yl)-1-Trityl-1H-Tetrazole) TTMB 5-[2-(4-methylphenyl)phenyl]-1-trityltetrazole N-(Triphenylmethyl)-5-(4'-Methylbiphenyl-2-Yl-)Tetrazole (Ttmb) Olmesartan TTMB impurity 1-[2-(diphenylmethyl)phenyl]-5-[2-(4-methylphenyl)phenyl]tetrazole Losartan Impurity 9 Olmesartan Medoxomil impurity 8/Olmesartan TTMB Impurity/5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 1H-Tetrazole, 5-(4'-methyl[1,1'-biphenyl]-2-yl)-1-(triphenylmethyl)- Losartan Impurity （5-?(4’-?Methyl-?[1,?1’-?biphenyl]?-?2-?yl)?-?1-?trityl-?1H-?tetrazole） 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole USP/EP/BP 5-?(4'-?Methyl-?[1,?1'-?biphenyl]?-?2-?yl)?-?1-?trityl-?1H-?tetrazole DISCONTINUED. Please see T889170 Olmesartan Medoxomil Impurity 24（Losartan Impurity 9） 5-(4'-Methylbiphenyl-2-yl)-1-trityl-1H-tetrazole 5-(4'-Methyl-[1,1'-biphenyl]-2-yl)-1-trityl-1H-tetrazole 124750-53-4 C34H29N4 C33H26N4 C33H22D4N4 Biphenyl & Diphenyl ether API intermediates Hypertension