10-Deacetylbaccatin III
- CAS No.
- 32981-86-5
- Chemical Name:
- 10-Deacetylbaccatin III
- Synonyms
- 10-DAB;10-DEACETYLBACCATIN;10-DAB Ⅲ;10-Deacetyl Baccatin lll;ó;NH24841;10DBA III;10-DAB-III;10-Deacetyl;10-Dab98.5%
- CBNumber:
- CB3447497
- Molecular Formula:
- C29H36O10
- Molecular Weight:
- 544.59
- MDL Number:
- MFCD00132913
- MOL File:
- 32981-86-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Docetaxel impurity E European Pharmacopoeia (EP) Reference Standard | Y0001452 | 15 mg | $118 |
| 10-desacetyl-baccatin III pharmaceutical secondary standard, certified reference material | PHR3007 | 50 mg | $592 |
| 10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC) | D3676 | 5mg | $382 |
| 10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC) | D3676 | 1mg | $108 |
| 10-Deacetylbaccatin III >98.0%(HPLC) | D4148 | 100mg | $100 |
| More product size | |||
| Melting point | 231-236 °C |
|---|---|
| Boiling point | 717℃ |
| alpha | -44.5 º (c=1, methanol 25 ºC) |
| Density | 1.2007 (rough estimate) |
| refractive index | 1.5376 (estimate) |
| Flash point | >110°(230°F) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | methanol: soluble, clear, colorless (5 mg + 0.1 mL MeOH) |
| form | Powder |
| pka | 11.50±0.70(Predicted) |
| color | white |
| Water Solubility | INSOLUBLE |
| InChIKey | YWLXLRUDGLRYDR-IYNRKYTHSA-N |
| SMILES | O1C[C@@]2(OC(C)=O)[C@@]3([H])[C@H](OC(=O)C4=CC=CC=C4)[C@@]4(O)C(C)(C)C(=C(C)[C@@H](O)C4)[C@@H](O)C(=O)[C@]3(C)[C@@H](O)C[C@@]12[H] |
| LogP | 0.156 (est) |
| CAS DataBase Reference | 32981-86-5(CAS DataBase Reference) |
| FDA UNII | 4K6EWW2Z45 |
| UNSPSC Code | 51102829 |
| NACRES | NA.85 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H335-H340-H350-H373 | |||||||||
| Precautionary statements | P201-P302+P352-P305+P351+P338-P308+P313 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 23/24/25 | |||||||||
| Safety Statements | 45-38-36/37/39-28A-24/25 | |||||||||
| RIDADR | 1544 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29329990 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Carc. 1B Eye Irrit. 2 Muta. 1B Skin Irrit. 2 STOT RE 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
10-Deacetylbaccatin III price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0001452 | Docetaxel impurity E European Pharmacopoeia (EP) Reference Standard | 32981-86-5 | 15 mg | $118 | 2025-07-31 | Buy |
| Sigma-Aldrich | PHR3007 | 10-desacetyl-baccatin III pharmaceutical secondary standard, certified reference material | 32981-86-5 | 50 mg | $592 | 2025-07-31 | Buy |
| Sigma-Aldrich | D3676 | 10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC) | 32981-86-5 | 5mg | $382 | 2025-07-31 | Buy |
| Sigma-Aldrich | D3676 | 10-Deacetylbaccatin III from Taxus baccata ≥95% (HPLC) | 32981-86-5 | 1mg | $108 | 2023-06-20 | Buy |
| TCI Chemical | D4148 | 10-Deacetylbaccatin III >98.0%(HPLC) | 32981-86-5 | 100mg | $100 | 2025-07-31 | Buy |
10-Deacetylbaccatin III Chemical Properties,Uses,Production
Chemical Properties
10-Deacetylbaccatin III is White Solid
Uses
10-Deacetylbaccatin III is a intermediate in the synthesis of Taxol and derivatives
Uses
10-Deacetyl Baccatin III is an impurity of Paclitaxel (P132500) and derivatives.
Uses
10-DAB (10-Deacetylbaccatin) is an antineoplastic agent and an anti-cancer intermediate. 10-DAB (10-Deacetylbaccatin) has gained great attention because of its partly excellent anti-cancer properties. 10-DAB (10-Deacetylbaccatin) can be gained from the le
Definition
ChEBI: 10-deacetylbaccatin III is a tetracyclic diterpenoid and a secondary alpha-hydroxy ketone. It is functionally related to a baccatin III.
General Description
10-Deacetylbaccatin III, also known as Paclitaxel Impurity 19, is an impurity of Paclitaxel. Paclitaxel is a chemotherapy drug. Chemotherapy is a treatment that destroys cancer cells using anti-cancer drugs. Paclitaxel is the non-branded name of the drug, but you may hear it called by one of its brand names such as Taxol. Some people are given a drug called nab-paclitaxel (Abraxane).
Biological Activity
10-dab (also known as 10-deacetylbaccatin) is an intermediate used for the preparation of taxol, an anti-leukemic and tumor-inhibiting agent isolated from the inner bark of the pacific yew tree taxus brevifolia as well as other species of the genus taxus. due to the low availability of taxol from its natural sources, 10-dab is used as a raw material for the preparation of taxol and its derivatives. being easily extracted from the annual cute of the yew leaves, 10-dab has a very folded chemical structure with the α hydroxyl group hindered at c-13 easily to form a hydrogen bond with the 4α acetyl group.f. gueritte-voegelein, v. senilh, b. david, d. guenard and p. potier. chemical studies of 10-deacetyl baccatin iii hemisynthesis of taxol derivatives. tetrahedron 1986; 42(16): 4451-4460
10-Deacetylbaccatin III Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei baicao biology science and technology co., ltd | +86-19131911055 +8617824879454 | zhang@hbbocao.com | China | 1029 | 58 |
| Guangzhou Tosun Pharmaceutical Limited | +86-18124244216 +86-18124244216 | info@upharm.cn | China | 998 | 58 |
| LIDE PHARMACEUTICALS LIMITED | +86-2558409506 +86-18913920737 | louis@lidepharma.com | China | 300 | 58 |
| Wuhan Quanjinci New Material Co.,Ltd. | +86-15271838296; +8615271838296 | kyra@quanjinci.com | China | 1512 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20129 | 58 |
| Wuhan JiyunZen Tech Co., Ltd. | +86-18062099985 | Amyjiyunzen@yeah.net | China | 672 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13620 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21600 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
View Lastest Price from 10-Deacetylbaccatin III manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-01-19 | 10-Deacetylbaccatin III
32981-86-5
|
US $5.00-0.50 / KG | 1KG | 99% hplc | 500TONS | Wuhan JiyunZen Tech Co., Ltd. | |
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2026-01-15 | 10-Deacetylbaccatin III
32981-86-5
|
US $29.00 / mL | 99.21% | 10g | TargetMol Chemicals Inc. | ||
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2025-12-03 | 10-Deacetylbaccatin III
32981-86-5
|
US $6666.00 / Kg/Bag | 2KG | 99 | 100kg | Baoji Guokang Healthchem Co., Ltd. |
-

- 10-Deacetylbaccatin III
32981-86-5
- US $5.00-0.50 / KG
- 99% hplc
- Wuhan JiyunZen Tech Co., Ltd.
-

- 10-Deacetylbaccatin III
32981-86-5
- US $29.00 / mL
- 99.21%
- TargetMol Chemicals Inc.
-

- 10-Deacetylbaccatin III
32981-86-5
- US $6666.00 / Kg/Bag
- 99
- Baoji Guokang Healthchem Co., Ltd.
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