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ChemicalBook >> CAS DataBase List >>N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE

N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE

N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE Structure
N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE structure
CAS No.
86847-84-9
Chemical Name:
N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE
Synonyms
N-(6-chloropyridin-2-yl)pivalamide;N-(6-chloropyridin-2-yl)-2,2-dimethylpropanamide;N-(6-chloro-2-pyridinyl)-2,2-dimethylpropanamide;Propanamide, N-(6-chloro-2-pyridinyl)-2,2-dimethyl-;N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE;N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE ISO 9001：2015 REACH
CBNumber:
CB3456211
Molecular Formula:
C10H13ClN2O
Molecular Weight:
212.68
MDL Number:
MFCD07366729
MOL File:
86847-84-9.mol
Last updated:2025-07-24 18:13:54
Product description Number Pack Size Price
N-(6-Chloro-pyridin-2-yl)-2,2-dimethyl-propionamide Aldrich ADE000326 1g $216
N-(6-Chloro-pyridin-2-yl)-2,2-dimethyl-propionamide C351040 250mg $55
N-(6-Chloropyridin-2-yl)pivalamide FC139893 500mg $65
N-(6-Chloropyridin-2-yl)pivalamide FC139893 1g $111
N-(6-Chloro-pyridin-2-yl)-2,2-dimethyl-propionamide 026142 500mg $161
More product size
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N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE Properties

Melting point 86-87 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling point 375.4±27.0 °C(Predicted)
Density 1.199±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form solid
pka 13.15±0.70(Predicted)
Appearance White to off-white Solid
UNSPSC Code 12352200

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  22
HazardClass  IRRITANT

N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich ADE000326 N-(6-Chloro-pyridin-2-yl)-2,2-dimethyl-propionamide Aldrich 86847-84-9 1g $216 2025-07-31 Buy
TRC C351040 N-(6-Chloro-pyridin-2-yl)-2,2-dimethyl-propionamide 86847-84-9 250mg $55 2021-12-16 Buy
Biosynth Carbosynth FC139893 N-(6-Chloropyridin-2-yl)pivalamide 86847-84-9 500mg $65 2021-12-16 Buy
Biosynth Carbosynth FC139893 N-(6-Chloropyridin-2-yl)pivalamide 86847-84-9 1g $111 2021-12-16 Buy
Matrix Scientific 026142 N-(6-Chloro-pyridin-2-yl)-2,2-dimethyl-propionamide 86847-84-9 500mg $161 2021-12-16 Buy
Product number Packaging Price Buy
ADE000326 1g $216 Buy
C351040 250mg $55 Buy
FC139893 500mg $65 Buy
FC139893 1g $111 Buy
026142 500mg $161 Buy

N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE Chemical Properties,Uses,Production

Synthesis

2-Amino-6-chloropyridine

45644-21-1

Pivaloyl chloride

3282-30-2

N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE

86847-84-9

An anhydrous dichloromethane solution of valeroyl chloride (0.32 mL, 2.57 mmol) was slowly added dropwise to an anhydrous dichloromethane suspension of 2-amino-6-chloropyridine (0.30 g, 2.33 mmol) and triethylamine (0.41 mL, 2.92 mmol) at 0 °C. The reaction mixture was kept stirred at 0 °C for 50 min, followed by gradual warming to room temperature to continue the reaction. After 5 hours of reaction, the mixture was poured into water and the organic phase was separated. The aqueous layer was extracted with dichloromethane and the combined organic phases were dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by Combiflash fast chromatography system using 0-15% ethyl acetate/hexane gradient elution to afford N-(6-chloropyridin-2-yl)-2,2-dimethylpropionamide (0.48 g, 2.28 mmol, 98% yield) as a white solid.

References

[1] Patent: WO2011/50245, 2011, A1. Location in patent: Page/Page column 118
[2] Patent: WO2008/128942, 2008, A1. Location in patent: Page/Page column 33
[3] Journal of Medicinal Chemistry, 2000, vol. 43, # 16, p. 3134 - 3147
[4] Patent: WO2017/211759, 2017, A1. Location in patent: Page/Page column 92
[5] Organic Process Research and Development, 2009, vol. 13, # 3, p. 555 - 566

N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE Preparation Products And Raw materials

Raw materials

2-Amino-6-chloropyridine Pivaloyl chloride Dichloromethane Triethylamine

Preparation Products

N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE Suppliers

Global( 104)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		+86-（0）57185586718; +8613336195806 sales@capot.com China 29735 60
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22963 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49975 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30229 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23541 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 20284 58
Dayang Chem (Hangzhou) Co.,Ltd. 		+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
CD Chemical Group Limited 		+8615986615575 info@codchem.com China 20342 58
PT CHEM GROUP LIMITED 		+86-85511178; peter68@ptchemgroup.com China 35425 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Hubei xin bonus chemical co. LTD 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Career Henan Chemica Co 		58
ANHUI WITOP BIOTECH CO., LTD 		58
Dideu Industries Group Limited 		58
Dayang Chem (Hangzhou) Co.,Ltd. 		58
CD Chemical Group Limited 		58
PT CHEM GROUP LIMITED 		58

View Lastest Price from N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE pictures 2025-11-18 N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE
86847-84-9
 US $1.10 / g 1g 99.00% 100 Tons min Dideu Industries Group Limited

N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE Spectrum

N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE(86847-84-9)1HNMR

86847-84-9(N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE)Related Search:

N-(6-CHLORO-2-PYRIDINYL)-ACETAMIDE N-(6-METHOXY-PYRIDIN-2-YL)-2,2-DIMETHYLPROPIONAMIDE N,N-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-amine N-(4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)propan-1-amine 4-Acetamido-3-(trifluoromethy)phenylboronic acid,
4-(N-PHENYLAMINOMETHYL)PHENYLBORONIC ACID 4-(2-[4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PHENOXY]-ETHYL)-MORPHOLINE N-(1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropyl)acetamide 3-(Diethylcarbamoyl)-2-fluorophenylboronic acid,pinacol ester N-(3-DIMETHYLAMINOPROPYL)-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)BENZAMIDE
N-(6-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-naphthalen-2-yl)MethanesulfonaMide N-(2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide N-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)propan-1-amine N-(4-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide N-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzamide
3-(N,N-DIMETHYLAMINO)PHENYLBORONIC ACID, PINACOL ESTER 3-(2-Methoxyethylaminocarbonyl)benzeneboronic acid pinacol ester 3-(4-FLUOROPHENYL)AMINOCARBONYLPHENYLBORONIC ACID PINACOL ESTER

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N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE N-(6-chloropyridin-2-yl)-2,2-dimethylpropanamide N-(6-chloropyridin-2-yl)pivalamide N-(6-chloro-2-pyridinyl)-2,2-dimethylpropanamide Propanamide, N-(6-chloro-2-pyridinyl)-2,2-dimethyl- N-(6-CHLORO-PYRIDIN-2-YL)-2,2-DIMETHYL-PROPIONAMIDE ISO 9001：2015 REACH 86847-84-9